Abstract:
:Covering: 1972 to 2011. This review covers the literature of prenylated quinone, hydroquinone and naphthoquinone marine natural products with reported cytotoxic and/or antioxidant properties. The structures, biological activity and, where applicable, the syntheses of 159 cytotoxic/antioxidant compounds, isolated from various marine organisms, are presented, while trends in the distribution of these cytotoxic metabolites, across the different marine phyla, are highlighted. Marine prenylated quinones, hydroquinones and naphthoquinones are of mixed polyketide and terpenoid biogenesis and recent biosynthetic studies of selected compounds are discussed.
journal_name
Nat Prod Repjournal_title
Natural product reportsauthors
Sunassee SN,Davies-Coleman MTdoi
10.1039/c2np00086esubject
Has Abstractpub_date
2012-05-01 00:00:00pages
513-35issue
5eissn
0265-0568issn
1460-4752journal_volume
29pub_type
杂志文章,评审abstract::Silybin, a secondary metabolite isolated from the seeds of the blessed milk thistle (Silybum marianum) was discovered as the first member of a new family of natural compounds called flavonolignans in 1959. Over the years it has received the research attention of many organic chemists. This research has resulted in a n...
journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/c3np70122k
更新日期:2014-09-01 00:00:00
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doi:10.1039/b616808f
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更新日期:2017-05-10 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/b612166g
更新日期:2008-02-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
doi:10.1039/c4np00065j
更新日期:2014-10-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/c2np20057k
更新日期:2012-10-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2013-04-01 00:00:00
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更新日期:2002-06-01 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/b303648k
更新日期:2003-12-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/c8np00067k
更新日期:2019-05-22 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/b103713g
更新日期:2002-02-01 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/c9np00016j
更新日期:2020-01-01 00:00:00
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doi:10.1039/b906678k
更新日期:2010-05-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/b316106b
更新日期:2005-02-01 00:00:00
abstract::Pantothenate is an essential metabolite for all biological systems, however, the biosynthetic pathway is limited to plants, eubacteria and archaea. This suggests that the pathway is a strong candidate for the discovery of novel antibiotic and herbicidal compounds. The enzymology of this short pathway in both bacteria ...
journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/b316419p
更新日期:2004-12-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/c0np00027b
更新日期:2011-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/c3np70092e
更新日期:2014-03-01 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/c6np00070c
更新日期:2016-10-26 00:00:00
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doi:10.1039/c4np00029c
更新日期:2014-09-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1039/b702742g
更新日期:2008-08-01 00:00:00
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doi:10.1039/d0np00033g
更新日期:2020-08-14 00:00:00
abstract::Covering: up to 2018 Ovothiols are sulfur-containing natural products biosynthesized by marine invertebrates, microalgae, and bacteria. These compounds are characterized by unique chemical properties suggestive of numerous cellular functions. For example, ovothiols may be cytoprotectants against oxidative stress, serv...
journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/c8np00045j
更新日期:2018-12-12 00:00:00
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更新日期:2004-10-01 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/c4np00013g
更新日期:2014-04-01 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
doi:10.1039/c7np00023e
更新日期:2017-07-06 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
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更新日期:2017-08-30 00:00:00
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journal_title:Natural product reports
pub_type: 杂志文章,评审
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更新日期:2006-04-01 00:00:00