Heparin and heparan sulfate: structure and function.

Abstract:

:This review covers the structure and function of heparin and heparan sulfate glycosaminoglycans. Their chemical structures are discussed, including recently developed methods for sequencing picomole to nanomole quantities of heparin- and heparan sulfate-derived oligosaccharides. The biosynthesis of heparin and heparan sulfate is reviewed as it relates to their diverse and varied structures, and their biological activities and functions are discussed. The literature up to August 2001 is reviewed, and 208 references are cited.

journal_name

Nat Prod Rep

journal_title

Natural product reports

authors

Rabenstein DL

doi

10.1039/b100916h

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

312-31

issue

3

eissn

0265-0568

issn

1460-4752

journal_volume

19

pub_type

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