Impact of vaccination against Haemophilus influenzae type b with and without a booster dose on meningitis in four South American countries.

abstract：:We tested whether pilus proteins of rabbit diarrhoeagenic Escherichia coli (RDEC-1), incorporated into biodegradable microspheres, could function as safe and effective oral immunogens in the rabbit diarrhoea model. The RDEC-1 adhesin, AF/R1, incorporated into poly(D,L-lactide-co-glycolide) microspheres, was administer...

journal_title：Vaccine

authors： McQueen CE,Boedeker EC,Reid R,Jarboe D,Wolf M,Le M,Brown WR

更新日期：1993-01-01 00:00:00

abstract：:We cloned six mycobacterial antigens into a mammalian expression vector as fusion proteins with the enhanced green fluorescent protein (EGFP). Plasmid DNA was injected intramuscularly, and the injection sites were examined 1 week later. Expression of each antigen-EGFP fusion protein was visualized as green fluorescenc...

journal_title：Vaccine

authors： Quinn A,Jiang W,Velaz-Faircloth M,Cobb AJ,Henry SC,Frothingham R

更新日期：2002-08-19 00:00:00

abstract：:The effects on the immunity in cattle of dosage and storage of oil-based inactivated vaccine incorporating the Gladysdale strain were examined. Storage at 4 degrees C for 12 or 24 months was found not to have any marked effect on the immunity conferred in the vaccinated cattle. A dosage of 0.5 ml was found to be as ef...

journal_title：Vaccine

authors： Garba SA,Terry RJ

更新日期：1986-12-01 00:00:00

abstract：:The use of pneumococcal polysaccharide vaccine (PPV) is low in some countries, maybe because of doubts regarding its efficacy. This meta-analysis aims at combining evidence from randomized trials of PPV assessing its efficacy in preventing Streptococcus pneumoniae related diseases in immunocompetent adults. In the fou...

journal_title：Vaccine

authors： Cornu C,Yzèbe D,Léophonte P,Gaillat J,Boissel JP,Cucherat M

更新日期：2001-09-14 00:00:00

abstract：:The immunogenicity of a candidate-inactivated vaccine prepared from SARS-CoV F69 strain was evaluated in Balb/c mice. Potent humoral immune responses were induced under the elicitation of three times of immunizations at 2-week intervals with this vaccine, combined with three types of adjuvants (Freund's adjuvant, Al(O...

journal_title：Vaccine

authors： Zhang CH,Lu JH,Wang YF,Zheng HY,Xiong S,Zhang MY,Liu XJ,Li JX,Wan ZY,Yan XG,Qi SY,Cui Z,Zhang B

更新日期：2005-05-02 00:00:00

abstract：BACKGROUND:Development of influenza vaccines that do not use embryonated eggs as the substrate for vaccine production is a high priority. We conducted this study to determine the protective efficacy a recombinant, baculovirus-expressed seasonal trivalent influenza virus hemagglutinin (rHA0) vaccine (FluBlok(®)). METHO...

journal_title：Vaccine

authors： Treanor JJ,El Sahly H,King J,Graham I,Izikson R,Kohberger R,Patriarca P,Cox M

更新日期：2011-10-13 00:00:00

abstract：:Paediatric patients with antibody deficiency may either be delayed in development of humoral immunity or may be persistently deficient in antibody production. To differentiate between these entities, we examined the 23-valent pneumococcal polysaccharide (PnPS) vaccine-induced IgM-, IgG- and IgA antibody responses in a...

journal_title：Vaccine

authors： Janssen WJ,Nierkens S,Sanders EA,Boes M,van Montfrans JM

更新日期：2015-11-17 00:00:00

abstract：:The influenza immunization program in North America has been primarily designed to provide direct benefit to vaccinated individuals at highest risk of serious influenza outcomes. Some evidence suggests that immunization of certain age groups may also extend indirect protective benefit to vulnerable populations. Our go...

journal_title：Vaccine

authors： Sebastian R,Skowronski DM,Chong M,Dhaliwal J,Brownstein JS

更新日期：2008-03-04 00:00:00

abstract：:A reverse transcriptase polymerase chain reaction (PCR) was used to amplify a 235 bp hypervariable region of the feline calicivirus (FCV) genome which encodes part of the capsid protein. Sequence from this region was used to compare viruses used in three attenuated vaccines to viruses isolated from vaccinated cats wit...

journal_title：Vaccine

authors： Radford AD,Bennett M,McArdle F,Dawson S,Turner PC,Glenn MA,Gaskell RM

更新日期：1997-08-01 00:00:00

abstract：:Experiments were carried out to examine the initial feasibility of immunizing infants and children with inactivated influenza virus vaccine combined with diphtheria-tetanus-pertussis (DTP) vaccine. Groups of mice were immunized with saline vaccine or vaccine mixed with DTP: three doses of vaccine were given 3 weeks ap...

journal_title：Vaccine

authors： Potter CW,Tamizifar H,Jennings R

更新日期：1995-02-01 00:00:00

abstract：PURPOSE:We tested the hypotheses that consistency and strength of clinician recommendation of the human papillomavirus (HPV) vaccination would be associated with vaccine delivery rates. METHODS:From October 2015 through January 2016, we conducted a survey of primary care clinicians (n=227) in Southeastern Minnesota to...

journal_title：Vaccine

authors： Finney Rutten LJ,St Sauver JL,Beebe TJ,Wilson PM,Jacobson DJ,Fan C,Breitkopf CR,Vadaparampil ST,MacLaughlin KL,Jacobson RM

更新日期：2017-10-27 00:00:00

abstract：:Previously, we showed that vaccination with the glycoprotein D (gD) gene of pseudorabies virus (PrV) delivered by Escherichia coli induced protective immune responses. In this study, we report that oral DNA vaccination with attenuated Salmonella choleraesuis carrying the PrV gD gene conferred protective immunity in mi...

journal_title：Vaccine

authors： Shiau AL,Chen YL,Liao CY,Huang YS,Wu CL

更新日期：2001-07-16 00:00:00

abstract：:In the present paper, an in vitro model was established in which the interaction between influenza virus-specific CD8+ T cells and human airway epithelial cells can be studied. To this end, the human lung epithelial cell line A549 was transduced with the HLA-A*0201 gene. This MHC class I allele is involved in the pres...

journal_title：Vaccine

authors： Rimmelzwaan GF,Boon AC,Geelhoed-Mieras MM,Voeten JT,Fouchier RA,Osterhaus AD

更新日期：2004-07-29 00:00:00

abstract：:The world is facing the rising emergency of SARS-CoV-2. The outbreak of COVID-19 has caused a global public health and economic crisis.Recent epidemiological studies have shown that a possible association of BCG vaccination program with decreased COVID-19-related risks, suggesting that BCG may provide protection again...

journal_title：Vaccine

authors： Tomita Y,Sato R,Ikeda T,Sakagami T

更新日期：2020-09-22 00:00:00

abstract：:In many industrialized countries, hepatitis A incidence rates have declined steadily in the past decades. Since future cohorts of non-vaccinated elderly will lack protection against disease and the burden of hepatitis A is higher with increasing age, this could be an argument in favour of taking preventive measures su...

journal_title：Vaccine

authors： Suijkerbuijk AW,Lugnér AK,van Pelt W,Wallinga J,Verhoef LP,de Melker HE,de Wit GA

更新日期：2012-07-27 00:00:00

abstract：:We recently identified a population of 10% of infants who respond with sub-protective antibody levels to most routine primary pediatric vaccinations due to altered innate and adaptive immune responses. We term these infants as low vaccine responders (LVRs). Here we report new data showing that TLR7/8 agonist - R848 st...

journal_title：Vaccine

authors： Surendran N,Nicolosi T,Pichichero M

更新日期：2016-11-11 00:00:00

abstract：:Bovine herpesvirus-1 (BHV-1) glycoprotein D (gD), an envelope glycoprotein, engenders mucosal and systemic immunity protecting cattle from viral infection. Production of gD with authentic immunogenicity is required for a subunit vaccine. We placed the truncated BHV-1 gD gene, lacking its putative transmembrane and cyt...

journal_title：Vaccine

authors： Zhu X,Wu S,Letchworth GJ 3rd

更新日期：1997-04-01 00:00:00

abstract：:110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody. After 10 years, 99.09% of inoc...

journal_title：Vaccine

authors： Bian GL,Ma R,Dong HJ,Ni HX,Hu FJ,Chen YR,Chen JQ,Zhou SY,Lin YX,Xu GZ

更新日期：2010-07-05 00:00:00

abstract：:A recombinant ricin vaccine from E. coli (RVEc™), was developed at the US Army Medical Research Institute of Infectious Diseases (USAMRIID) and assessed in an FDA sponsored Phase 1a clinical trial. At the maximum dosage, two of the study participants developed physiological responses that were elevated to the level of...

journal_title：Vaccine

authors： Montgomery VA,Lindsey CY,Smith LA,Webb RP

更新日期：2021-01-15 00:00:00

abstract：:Travellers often present late for the third dose of hepatitis B vaccination and measuring anti-HBs serology is common practice to ensure that these individuals are protected. We assessed the adequacy of immune response in 86 healthy travellers who had their third dose of hepatitis B (HB) vaccine performed more than 1 ...

journal_title：Vaccine

authors： Jackson Y,Chappuis F,Mezger N,Kanappa K,Loutan L

更新日期：2007-04-30 00:00:00

abstract：BACKGROUND:Each year a substantial number of Dutch elderly suffers from herpes zoster (HZ), caused by the reactivation of the varicella zoster virus (VZV). A potential complication of HZ is postherpetic neuralgia (PHN) which results in a prolonged loss of quality of life. A large randomized clinical trial, labelled the...

journal_title：Vaccine

authors： de Boer PT,Pouwels KB,Cox JM,Hak E,Wilschut JC,Postma MJ

更新日期：2013-02-18 00:00:00

abstract：AIMS:The study was designed to evaluate a novel cationic lipid DNA adjuvant (N3) and its function for HIV-1gp160/rev DNA plasmid delivered intranasally. The primary N3/HIV-DNA plasmid immunizations were boosted intranasally with a gp41 peptide in a anionic L3 adjuvant. This novel prime-boost strategy of mucosal immuniz...

journal_title：Vaccine

authors： Hinkula J,Devito C,Zuber B,Benthin R,Ferreira D,Wahren B,Schröder U

更新日期：2006-05-22 00:00:00

abstract：:Domestic dogs constitute the main reservoir of Leishmania infantum and play a key role in transmission to humans. The main tool for controlling infection spread is a safe and effective vaccine, as successful immunization of dogs could significantly reduce the incidence of human visceral leishmaniosis (VL) and is the m...

journal_title：Vaccine

authors： Cacheiro-Llaguno C,Parody N,Renshaw-Calderón A,Osuna C,Alonso C,Carnés J

更新日期：2020-01-22 00:00:00

abstract：:Cytotoxic T cells are the main antigen-specific effector cells of the cellular immune system and MHC class I restricted cytotoxic T-lymphocyte (CTL) responses in mice, acting against the HIV-1 envelope protein, are known to be predominantly directed against an amino acid sequence in the third hypervariable domain. We ...

journal_title：Vaccine

authors： Achour A,Picard O,Mbika JP,Willer A,Snart R,Bizzini B,Carelli C,Burny A,Zagury D

更新日期：1993-01-01 00:00:00

abstract：:The World Health Organization's Expanded Programme on Immunization has led to a dramatic rise in worldwide vaccination rates over the past 40years, yet 19.4 million infants remain underimmunized each year. Many of these infants have received at least one vaccine dose but may remain unprotected because they did not rec...

journal_title：Vaccine

authors： Guarecuco R,Lu J,McHugh KJ,Norman JJ,Thapa LS,Lydon E,Langer R,Jaklenec A

更新日期：2018-05-24 00:00:00

abstract：:Maltoporin (LamB) is a family of outer membrane proteins. There has been no report of immunological characteristics of LamB in the Vibrio species so far. In this study, lamB genes from eight Vibrio strains were cloned and sequenced. The bioinformatics analysis indicated that sequence similarities of LamB proteins were...

journal_title：Vaccine

authors： Lun J,Xia C,Yuan C,Zhang Y,Zhong M,Huang T,Hu Z

更新日期：2014-02-07 00:00:00

abstract：BACKGROUND:A randomized, double-blind, placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a pentavalent live human-bovine reassortant rotavirus vaccine (RotaTeq™, RV5) against rotavirus gastroenteritis (RVGE). METHODS:4040 participants aged 6-12weeks were...

journal_title：Vaccine

authors： Mo Z,Mo Y,Li M,Tao J,Yang X,Kong J,Wei D,Fu B,Liao X,Chu J,Qiu Y,Hille DA,Nelson M,Kaplan SS

更新日期：2017-10-13 00:00:00

abstract：:Bovine tuberculosis (bTB) is increasing in incidence in the UK. Effective control strategies could involve vaccination; BCG, either alone or in prime-boost strategies, remains the most effective vaccine against bovine tuberculosis. However, BCG vaccination of cattle would require development of diagnostic tests able t...

journal_title：Vaccine

authors： Sopp P,Coad M,Hewinson G,Howard CJ,Cheallaigh CN,Keane J,Harris J,Hope JC

更新日期：2008-10-09 00:00:00

abstract：:Six peptides, A, B1, B, C, D and E derived from the primary sequence of Schistosoma mansoni glyceraldehyde 3-phosphate dehydrogenase (SG3PDH) were selected based on lowest homology to human G3PDH and used for immunization of BALB/c mice. Peptides B1 and D induced immunoglobulin (Ig) G1, IgG2a and IgG2b antibodies that...

journal_title：Vaccine

authors： Tallima H,Montash M,Veprek P,Velek J,Jezek J,El Ridi R

更新日期：2003-07-04 00:00:00

abstract：OBJECTIVES:The aims of this study were to (a) assess knowledge of official vaccination recommendations and attitudes towards vaccinations among adults and (b) examine their association with vaccination uptake among adults. METHODS:This study was part of the HaBIDS study (Hygiene and Behaviour Infectious Diseases Surve...

journal_title：Vaccine

authors： Akmatov MK,Rübsamen N,Deyneko IV,Karch A,Mikolajczyk RT

更新日期：2018-04-25 00:00:00