Abstract：
:110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody. After 10 years, 99.09% of inoculated children remained positive for serum anti-HAV antibody, with a geometric mean concentration (GMC) of 61.59mIU/mL. GMC values following a secondary immunization in children with antibody levels <20mIU/mL were significantly elevated (567.9mIU/mL), compared with the primary injection alone. Havrix appears to induce persistent immunity and potent immune memory.
journal_name
Vaccinejournal_title
Vaccineauthors
Bian GL,Ma R,Dong HJ,Ni HX,Hu FJ,Chen YR,Chen JQ,Zhou SY,Lin YX,Xu GZdoi
10.1016/j.vaccine.2010.04.096subject
Has Abstractpub_date
2010-07-05 00:00:00pages
4798-801issue
30eissn
0264-410Xissn
1873-2518pii
S0264-410X(10)00634-1journal_volume
28pub_type
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