Abstract:
BACKGROUND:As global effort is made towards measles elimination, the use of innovative technology to enhance planning for the campaign has become critical. GIS technology has been applied to track polio vaccination activities in Nigeria with encouraging outcomes. Despite numerous measles vaccination campaigns after the first catch up campaign in 2005, sub-optimal outcomes of previous measles supplemental immunization activities necessitated the use of innovative ideas to achieve better outcomes especially when planning for the 2017/2018 measles vaccination campaign. This led to the application of the use of the GIS technology for the Northern states in 2017/2018 campaign. This study is a report of what was achieved with the use of the GIS in the 2017/2018 measles vaccination campaign in Nigeria. METHODS:GIS generated ward maps were used for the microplanning processes for the 2017/2018 measles vaccination campaign. These ward maps had estimates of the target population by settlements, the number and location of vaccination posts ensuring that a vaccination post is sited within one-kilometer radius of a settlement, and the number of teams needed to support the vaccination campaign as well as the catchment area and daily implementation plans. The ward microplans were verified by checking for accuracy and consistency of the target population, settlements, number of teams, vaccination posts and daily implementation work plans using a standard checklist. The ward maps were deployed into use for the measles vaccination campaign after the state team driven validation and verification by the National team (Government and Partners) RESULTS: The Northern states that applied the GIS technology had a closer operational target population to that on the verified microplan than those of the non-GIS technology states. Greater than 90% of the ward maps had all that is expected in the maps - i.e settlements, target populations, and vaccination posts captured, except Kaduna, Katsina and Adamawa states. Of all enumeration areas sampled during the post-campaign survey in states with GIS ward maps, none had a zero-vaccination coverage of the surveyed children, with the exception of one in Borno state that had security issues. In the post campaign coverage survey, the percentage of responses that gave vaccination post being too far as a reason for non-vaccination of children in the Northern zones that used GIS generated ward maps was less than half the rate seen in the southern zones where the GIS microplanning was not used. CONCLUSION:The use of GIS-generated wards maps improved the quality of ward micro plans and optimized the placement of vaccination posts, resulting in a significant reduction in zero-dose clusters found during the post campaign coverage survey.
journal_name
Vaccinejournal_title
Vaccineauthors
Oteri J,Idi Hussaini M,Bawa S,Ibizugbe S,Lambo K,Mogekwu F,Wiwa O,Seaman V,Kolbe-Booysen O,Braka F,Nsubuga P,Shuaib Fdoi
10.1016/j.vaccine.2021.01.021subject
Has Abstractpub_date
2021-01-18 00:00:00eissn
0264-410Xissn
1873-2518pii
S0264-410X(21)00025-6pub_type
杂志文章相关文献
VACCINE文献大全abstract::HIV-infected individuals have impaired immune responses to vaccines and high rates of pneumococcal disease. The effect of vitamin A and zinc supplementation on the immunogenicity of a 7-valent pneumococcal CRM-197 conjugate vaccine (PC-7) was evaluated in 118 HIV+ injection drug users. Subjects were randomized to oral...
journal_title:Vaccine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.vaccine.2005.09.047
更新日期:2006-03-06 00:00:00
abstract::We have found out that transfection of the RTG-2 cell line with the viral haemorrhagic septicaemia virus (VHSV) glycoprotein G (G(VHSV))-coding plasmid induces an anti-VHSV state, similar to that induced by poly I:C. Taking the advantage of the constitutive expression of toll-like receptor 9 gene (tlr9) in RTG-2 cells...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2010.11.021
更新日期:2011-01-17 00:00:00
abstract::Dendritic cells (DCs) have been identified as the most effective antigen-presenting cell (APC), much attention has been directed toward the use of DCs in vaccine strategies for the treatment of cancer or chronic virus infection. B7-H1 (PD-L1) is a ligand for programmed cell death-1 (PD-1) and does not bind to other CD...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2011.11.076
更新日期:2012-01-17 00:00:00
abstract:OBJECTIVE:Rotavirus is the most common cause of severe diarrhea in children. Two rotavirus vaccines (RotaTeq and Rotarix) have been licensed in Taiwan. We have investigated whether routine infant immunization with either vaccine could be cost-effective in Taiwan. METHODS:We modeled specific disease outcomes including ...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2009.01.023
更新日期:2009-03-04 00:00:00
abstract::Two hundred and fifty children born in 1967 and vaccinated with killed polio vaccine in Sweden were followed for 18 years and tested for neutralizing antibodies against polio. All of them had demonstrable antibodies at the age of 18. Sixty-four children were tested in samples collected throughout the years. After a mo...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/0264-410x(90)90244-g
更新日期:1990-10-01 00:00:00
abstract::Enterotoxigenic E. coli (ETEC) are an important cause of diarrhea in developing countries, especially among indigenous children and travelers. In this randomized, double-blind, placebo-controlled trial, a live, attenuated CS1/CS3 ETEC strain, PTL-003, was tested as a potential vaccine strain. Thirty-three subjects dra...
journal_title:Vaccine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.vaccine.2008.06.064
更新日期:2008-08-26 00:00:00
abstract::Bacterial flagellin activates the innate immune system and ultimately the adaptive immune system through a Toll-like receptor 5 (TLR5)-dependent signaling mechanism. Given that TLR5 is widely distributed in epithelia, flagellin is currently being developed as a mucosal adjuvant. Flagellin FliC from Salmonella enterica...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2018.12.009
更新日期:2019-01-21 00:00:00
abstract::Cell culture-based manufacturing of influenza vaccines is ideally based on easily scalable platforms using suspension cells that grow in chemically defined media. Consequently, different adherent cell lines selected for high virus yields were adapted to grow in suspension culture. This includes the MDCK suspension cel...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2013.09.051
更新日期:2013-11-19 00:00:00
abstract::Influenza A/H1N1 new vaccine helps control disease spread. Cross-sectional survey was conducted at PHC & Emergency Departments in Qatar to determine influenza A/H1N1 vaccination rate among HCWs and associated factors, 523 HCWs were enrolled. The study showed that 13.4% HCWs received vaccination. Feeling protected stro...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2010.08.093
更新日期:2011-03-03 00:00:00
abstract::Since 1999, Italy has been challenged by several epidemics of Notifiable Avian Influenza (NAI) of the H5 and H7 subtypes, occurring in the densely populated poultry areas of northern part of the country. Vaccination with a conventional vaccine containing a seed strain with a different neuraminidase subtype to the fiel...
journal_title:Vaccine
pub_type: 杂志文章,评审
doi:10.1016/j.vaccine.2007.01.113
更新日期:2007-06-28 00:00:00
abstract:BACKGROUND:Previous reports mostly from Europe suggested an association between an occurrence of narcolepsy and an influenza A(H1N1)pdm09 vaccine adjuvanted with AS03 (Pandemrix(®)). During the 2009 H1N1 pandemic vaccination campaign, the Korean military performed a vaccination campaign with one type of influenza vacci...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2015.07.055
更新日期:2015-09-11 00:00:00
abstract::Interaction of native proteinaceous antigens during the recognition and the effector phases of an immune response leads to antigenic conformational modifications which may elicit additional specific immune response. Protein cross-linking and conformation restraining formaldehyde and glutaraldehyde have been extensivel...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/s0264-410x(98)00121-2
更新日期:1998-12-01 00:00:00
abstract::To evaluate the utility of plasmid DNA vaccination against disease caused by herpes simplex virus (HSV), we compared the strength of protection against lethal challenge following natural virus infection with that following vaccination with a plasmid encoding HSV glycoprotein gD (gD-DNA). We further determined the cell...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/s0264-410x(00)00380-7
更新日期:2001-01-08 00:00:00
abstract::In a phase I/II dose escalation study, varying volumes (0.1 ml, 0.5 ml, 1.0 ml and 2.0 ml) of 7-valent pneumococcal conjugate vaccine (PCV) (Prevnar or 0.5 ml of 23-valent pneumococcal polysaccharide vaccine (PPV) were administered to 220 adults 70 through 79 years of age previously vaccinated with 0.5 ml PPV at age 6...
journal_title:Vaccine
pub_type: 临床试验,杂志文章
doi:10.1016/j.vaccine.2005.02.017
更新日期:2005-05-25 00:00:00
abstract::Carbopol is a polyanionic carbomer used in man for topical application and drug delivery purposes. However parenteral administration of Carbopol in animal models results in systemic adjuvant activity including strong pro-inflammatory type-1 T-cell (Th1) polarization. Here we investigated potential pathways of immune a...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2016.03.025
更新日期:2016-04-27 00:00:00
abstract::Fluid cholera vaccine was examined for its stability at 4-8 degrees C, 20-25 degrees C and 37 degrees C with regard to the number of organisms present and the total nitrogen content. Ten batches of fluid cholera vaccine manufactured at the Central Research Institute, Kasauli, India were taken for the study. The number...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/0264-410x(84)90046-x
更新日期:1984-12-01 00:00:00
abstract::T lymphocytes play a central role in the generation of a protective immune response in many microbial infections. After immunization, dendritic cells take up microbial antigens and traffic to draining lymph nodes where they present processed antigens to naïve T cells. These naïve T cells are stimulated to proliferate ...
journal_title:Vaccine
pub_type: 杂志文章,评审
doi:10.1016/s0264-410x(02)00407-3
更新日期:2003-01-17 00:00:00
abstract::Understanding the requirements for protection against pneumococcal carriage and pneumonia will greatly benefit efforts in controlling these diseases. Several antigens, in addition to the polysaccharide capsule, have been implicated in both the virulence and protective immunity against Streptococcus pneumoniae; one of ...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2011.12.020
更新日期:2012-02-01 00:00:00
abstract::The HA1 domain of influenza A viruses is critical for immune escape and host receptor recognition. However, the association between HA1 evolution and host species-specific adaptations remains unclear. We have identified the amino acid sites that are related to the host species-specific adaptations by systematically co...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2010.09.071
更新日期:2010-11-23 00:00:00
abstract::Safe RSV vaccine development has challenged the medical community since a formalin-killed RSV vaccine caused disease exacerbation in the 1960s. Disease was replicated using the bovine RSV system in one of two studies. The studies differed in viral protein dose and length of time between vaccination and infection. Dise...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2003.10.024
更新日期:2004-03-29 00:00:00
abstract:OBJECTIVES:Public health authorities have the resources to conduct efficient immunization reminder interventions to improve vaccine uptake. The objective of this initiative was to design and implement a cost-effective centralized HPV vaccine reminder using New York State Immunization Information System data as one of f...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2018.06.056
更新日期:2018-08-06 00:00:00
abstract::The greatest risk from live-attenuated vaccines is reversion to virulence. Particular concerns arise for RNA viruses, which exhibit high mutation frequencies. We examined the stability of 3 attenuation strategies for the alphavirus, Venezuelan equine encephalitis virus (VEEV): a traditional, point mutation-dependent a...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2011.01.055
更新日期:2011-03-09 00:00:00
abstract::Helicobacter pylori neutrophil-activating protein (NAP) is a toll-like receptor 2 (TLR2) agonist and potent immunomodulator inducing Th1-type immune response. Here we present data about characterization of the humoral immune response against NAP-tagged antigens, encoded by attenuated measles virus (MV) vector platform...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2013.07.085
更新日期:2013-10-01 00:00:00
abstract::A small number of serotypes are responsible for most invasive pneumococcal disease in children worldwide. Serotypes 1 and 5 were among the first pneumococcal serotypes to be identified, reflecting their great prominence as causes of disease in the early part of the 20th century. In the antibiotic era, these serotypes ...
journal_title:Vaccine
pub_type: 杂志文章,评审
doi:10.1016/j.vaccine.2006.09.009
更新日期:2007-03-22 00:00:00
abstract::Oral administration of antigen is known to be appropriate for some vaccine purposes as well as oral tolerance induction. In the present study, oral administration of beta-lactoglobulin (BLG) loaded poly(D,L-lactide-co-glycolide) (D,L-PLG) microspheres induced tolerance was evaluated. A single feeding of 5 micrograms o...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/s0264-410x(99)00384-9
更新日期:2000-01-18 00:00:00
abstract::A conjugate vaccine against meningococcus A and C was prepared using the non-toxic mutant of diphtheria toxin CRM 197 as a carrier protein. Capsular polysaccharides of Neisseria meningitidis group A and C were hydrolysed and the resulting oligosaccharides were then coupled to CRM 197 in order to obtain conjugates with...
journal_title:Vaccine
pub_type: 临床试验,杂志文章
doi:10.1016/0264-410x(92)90091-w
更新日期:1992-01-01 00:00:00
abstract::It has been known that influenza A virus infection induces a cross-protective immunity against infection by viruses with different subtypes of viral envelope proteins, hemagglutinin (HA) and neuraminidase (NA). This heterosubtypic immunity is generally mediated by cytotoxic T lymphocytes (CTL) reactive to specific epi...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/s0264-410x(03)00234-2
更新日期:2003-07-04 00:00:00
abstract:INTRODUCTION:Institutionalized mentally retarded subjects are well-known to be at-risk for HBV infection. We studied the persistence of vaccine-induced anti-HBs antibodies and the robustness of the HBsAg-specific immune memory in this population, 18-20 years after the first vaccine dose. MATERIALS AND METHODS:Non-immu...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2012.05.044
更新日期:2012-07-06 00:00:00
abstract:BACKGROUND:In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan's elimination status. MET...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2019.08.085
更新日期:2019-10-08 00:00:00
abstract::A family of platyhelminth tegument-specific proteins comprising of one or two calcium ion binding EF-hand and a dynein light chain-like domain, termed tegumental proteins, are considered as candidates of vaccine. In this study, we cloned and characterized SjTP22.4, a novel membrane-anchored tegumental protein in Schis...
journal_title:Vaccine
pub_type: 杂志文章
doi:10.1016/j.vaccine.2012.05.056
更新日期:2012-07-20 00:00:00