Preinvasive lesions of the bronchus.

abstract：:Sleep-related breathing disorders are strongly associated with increased risk of stroke independent of known risk factors. The direction of causation favors sleep-disordered breathing leading to stroke rather than the other way around, although definitive proof of this awaits the results of prospective cohort studies....

journal_title：Clinics in chest medicine

authors： Yaggi H,Mohsenin V

更新日期：2003-06-01 00:00:00

abstract：:The hyperventilation seen in asthma is due to an increase in respiratory drive. This may be reflected by increased neural output to the respiratory muscles and probably by alterations in the respiratory pattern. This increased respiratory drive is most likely in response to irritant receptor stimulation in the lung. O...

journal_title：Clinics in chest medicine

authors： Schiff M

更新日期：1980-01-01 00:00:00

abstract：:The synthesis of nitric oxide (NO) and its targets are reviewed physiologically during sepsis and wound healing, a self-limiting process in which mechanisms are still identified incompletely. NO also plays an active and direct role during infection, aimed at protecting the host and destroying the microbe. During septi...

journal_title：Clinics in chest medicine

authors： Payen D,Bernard C,Beloucif S

更新日期：1996-06-01 00:00:00

abstract：:Recent events have underscored the importance of proper diagnosis and management of patients with inhalation injury. Clinicians who care for individuals who have sustained inhalation damage to their respiratory tract need to take a careful exposure history and be alert to possibilities of delayed effects and clinical ...

journal_title：Clinics in chest medicine

authors： Rabinowitz PM,Siegel MD

更新日期：2002-12-01 00:00:00

abstract：:The pharmacologic treatment of chronic obstructive pulmonary disease (COPD) differs from that of asthma in several respects. Oral therapy should be the keystone, using a long-acting theophylline or a beta 2-sympathomimetic agent. The addition of a metered dose inhalant aerosol provides additive benefit with low toxici...

journal_title：Clinics in chest medicine

authors： Ziment I

更新日期：1990-09-01 00:00:00

abstract：:Available data show that Africa, together with the Americas and western and central Europe, reported the lowest prevalence of multidrug-resistant tuberculosis (MDR-TB). However, sub-Saharan Africa has a high TB incidence and the highest human immunodeficiency virus (HIV) prevalence in the world, and because of the hig...

journal_title：Clinics in chest medicine

authors： Schaaf HS,Moll AP,Dheda K

更新日期：2009-12-01 00:00:00

abstract：:As recently as the 1992 Report of the American Thoracic Society Workshop on Lung Transplantation, no QOL facts were given and no knowledge gaps related to QOL outcomes were cited. Even at the present time, the information in that area is based on a relatively small set of preliminary reports. Current information indic...

journal_title：Clinics in chest medicine

authors： Gross CR,Raghu G

更新日期：1997-06-01 00:00:00

abstract：:Leptospirosis is a worldwide disease. In this time of globalization knowledge about leptospirosis is important. Although pulmonary involvement has an incidence varying from 20% to 70% and its exteriorization may vary from mild to severe, The severe form appears to be becoming more prevalent (at least in Brazil) and ma...

journal_title：Clinics in chest medicine

authors： Carvalho CR,Bethlem EP

更新日期：2002-06-01 00:00:00

abstract：:The mechanisms for exercise intolerance in chronic obstructive pulmonary disease are complex and multifaceted. Although ventilatory limitation caused by abnormal pulmonary function is a major contributor to this phenomenon, other factors may play an important role in limiting exercise. These other factors include depr...

journal_title：Clinics in chest medicine

authors： Nici L

更新日期：2000-12-01 00:00:00

abstract：:Hypersensitivity pneumonitis (HP) represents a group of immunologically mediated lung disorders provoked by recurrent exposure to various environmental agents. HP is multifaceted and may mimic almost any interstitial lung disease, some infectious diseases,and even bronchiolar disorders. In the absence of a diagnostic ...

journal_title：Clinics in chest medicine

authors： Selman M

更新日期：2004-09-01 00:00:00

abstract：:Our understanding of chronic bronchitis has been hampered by the fact that the diagnosis is based upon historical evidence of recurrent cough and sputum without any requirement that certain physiologic or microscopic criteria be met. Despite the fact that epidemiological studies have implicated viruses, bacteria, and ...

journal_title：Clinics in chest medicine

authors： Sachs FL

更新日期：1981-01-01 00:00:00

abstract：:Inhaled corticosteroids (ICSs), when used in combination with long-acting bronchodilators, reduce the risk of exacerbations and improve health-related quality of life in patients with chronic obstructive pulmonary disease (COPD) compared with bronchodilator or ICS therapy alone. Potential side effects of ICSs include ...

journal_title：Clinics in chest medicine

authors： Mkorombindo T,Dransfield MT

更新日期：2020-09-01 00:00:00

abstract：:This article review available strategies for mechanically ventilating patients with the adult respiratory distress syndrome. The authors first present the conventional strategies of mechanical ventilation: volume-limited mechanical ventilation with positive end-expiratory pressure (PEEP) at normal inspiratory-expirato...

journal_title：Clinics in chest medicine

authors： Stoller JK,Kacmarek RM

更新日期：1990-12-01 00:00:00

abstract：:Patients with diagnosed or suspected lung cancer first require appropriate staging and proven anatomic resectability. Excellent pre-operative spirometric data (FEV1 > 2.0 L, > 60% predicted) should recommend the patient for surgery immediately without further testing. Those whose preoperative FEV1 is less than 60% pre...

journal_title：Clinics in chest medicine

authors： Gilbreth EM,Weisman IM

更新日期：1994-06-01 00:00:00

abstract：:This article focuses primarily on the recent literature on abdominal compartment syndrome (ACS) and the definitions and recommendations published by the World Society for the Abdominal Compartment Syndrome. The definitions regarding increased intra-abdominal pressure (IAP) are listed and are followed by an overview of...

journal_title：Clinics in chest medicine

authors： Malbrain ML,De laet IE

更新日期：2009-03-01 00:00:00

abstract：:Medications can significantly increase weight loss compared with placebo in most trials. In general, patients can expect a weight loss of 8% to 10% from baseline provided they adhere to the weight-loss program and take medications regularly. All medications have side effects that need to be considered before initiatin...

journal_title：Clinics in chest medicine

authors： Bray GA

更新日期：2009-09-01 00:00:00

abstract：:Interventional pulmonology encompasses diagnostic and therapeutic bronchoscopic procedures, and pleural interventions. In the last 10 years older techniques have been refined and exciting new technologies have extended the reach and application of the instruments used. The main areas within pulmonary medicine for whic...

journal_title：Clinics in chest medicine

authors： Morgan RK,Ernst A

更新日期：2011-03-01 00:00:00

abstract：:Massive hemoptysis accounts for a minority of all patients with hemoptysis but poses a major challenge for the acute and long-term treatment. Massive hemoptysis can lead to asphyxiation and airway obstruction, shock, and exsanguination. Bronchoscopy plays an integral part in managing massive hemoptysis in diagnosis an...

journal_title：Clinics in chest medicine

authors： Dweik RA,Stoller JK

更新日期：1999-03-01 00:00:00

abstract：:Mechanical ventilation has become a very common and well-accepted practice in modern intensive care units. The use of the mechanical ventilator has progressed from being a support system during surgery and for acutely ill patients to being used in both moderate and long-term life support in patients with inadequate ve...

journal_title：Clinics in chest medicine

authors： Grum CM,Chauncey JB

更新日期：1988-03-01 00:00:00

abstract：:The treatment of idiopathic pulmonary fibrosis (IPF) remains controversial. The benefits of conventional treatment with corticosteroids plus either azathioprine or cyclophosphamide have not been established in randomized, controlled trials. Other treatment strategies have been suggested as understanding of the pathoge...

journal_title：Clinics in chest medicine

authors： Nathan SD

更新日期：2006-03-01 00:00:00

abstract：:Individualized management of asthma requires consideration of single or combined pharmacologic alternatives. This article reviews experimental and clinical data on the efficacy, safety, mode of action, and therapeutic indications for cromolyn and related inhalational compounds; ketotifen; alpha-adrenergic blockers; ca...

journal_title：Clinics in chest medicine

authors： Falliers CJ,Tinkelman DG

更新日期：1986-09-01 00:00:00

abstract：:Gram-negative bacteria gain access to the bloodstream by evading host defenses. Once in circulation, lipopolysaccharide interacts with the host receptor CD14 and initiates the host's immune response. Lipolysaccharide stimulates the host to produce a cascade of mediators that activate and target leukocytes, opsonize th...

journal_title：Clinics in chest medicine

authors： Marsh CB,Wewers MD

更新日期：1996-06-01 00:00:00

abstract：:In general, lung involvement in connective tissue disorders has not been as well defined as has isolated interstitial lung disease; this applies particularly to bronchiolitis, which occurs infrequently. The low prevalence of bronchiolitis may reflect difficulties in making the diagnosis in mild to moderate disease; at...

journal_title：Clinics in chest medicine

authors： Wells AU,du Bois RM

更新日期：1993-12-01 00:00:00

abstract：:In the past 3 years, lung volume reduction surgery has become the most controversial topic in the clinical management of patients with emphysema. Although literature has added to the understanding of the procedure, many important issues remain unclear. This article emphasizes functional and basic physiologic changes t...

journal_title：Clinics in chest medicine

authors： Sciurba FC

更新日期：1997-06-01 00:00:00

abstract：:Because of physiologic changes associated with aging and the development of chronic illness, the elderly will continue to be at risk for catastrophic illnesses including adult respiratory distress syndrome (ARDS). Current management of elderly patients with ARDS is only supportive and focused on avoiding complications...

journal_title：Clinics in chest medicine

authors： Griffith D,Idell S

更新日期：1993-09-01 00:00:00

abstract：:From our studies, it is clear that diaphragm muscle neuromotor control is responsive to alterations in innervation and activation. These adaptations to altered use appear to be most pronounced among fast-twitch motor units composed of type II muscle fibers. Because the plasticity involves diminished contractile streng...

journal_title：Clinics in chest medicine

authors： Sieck GC

更新日期：1994-12-01 00:00:00

abstract：:Pregnancy induces significant physiologic stresses on the pulmonary and cardiovascular systems that may precipitate respiratory compromise. In addition, certain disease states that are unique to the pregnant woman, such as amniotic fluid emboli syndrome, may be associated with respiratory failure. The physiologic chan...

journal_title：Clinics in chest medicine

authors： Pereira A,Krieger BP

更新日期：2004-06-01 00:00:00

abstract：:Bacterial pneumonias occur with increased frequency and can be associated with increased morbidity in the HIV-infected population compared with normals. The pathogens that most frequently cause community-acquired pneumonias are S. pneumoniae, H. influenzae, and occasionally S. aureus. These pneumonias usually respond ...

journal_title：Clinics in chest medicine

authors： Fels AO

更新日期：1988-09-01 00:00:00

abstract：:Pneumonia, acute bronchitis, and sinusitis are common infections encountered by the pulmonary specialist. Such conditions are usually treated with antibiotics, and their use requires an understanding of their pharmacokinetic properties as well as their antimicrobial spectrum and adverse side effects. ...

journal_title：Clinics in chest medicine

authors： Segreti J,Trenholme GM

更新日期：1986-09-01 00:00:00

abstract：:Most gravidas with asthma can be managed with an inhaled beta-adrenergic agonist (terbutaline or epinephrine) and beclomethasone dipropionate. The administration of prednisone to control exacerbation of asthma is appropriate and should not be withheld if current medications are inadequate. The outcome of pregnancy in ...

journal_title：Clinics in chest medicine

authors： Greenberger PA

更新日期：1992-12-01 00:00:00