Mechanisms and measures of exercise intolerance in chronic obstructive pulmonary disease.

Abstract:

:The mechanisms for exercise intolerance in chronic obstructive pulmonary disease are complex and multifaceted. Although ventilatory limitation caused by abnormal pulmonary function is a major contributor to this phenomenon, other factors may play an important role in limiting exercise. These other factors include depressed cardiac function, respiratory and peripheral muscle weakness, nutritional imbalances, and psychologic factors. The assessment of the pulmonary patient who complains of decreased functional status must include examination and consideration of all these variables. Only by addressing and treating the combination of these variables as they present in an individual patient will clinicians have the potential to impact that individual's functional status and quality of life.

journal_name

Clin Chest Med

authors

Nici L

doi

10.1016/s0272-5231(05)70178-7

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

693-704

issue

4

eissn

0272-5231

issn

1557-8216

pii

S0272-5231(05)70178-7

journal_volume

21

pub_type

杂志文章,评审
  • Beyond the Golden Hours: Caring for Septic Patients After the Initial Resuscitation.

    abstract::Recognition and management of agitation, delirium, and pain are key areas. Reduced use of sedatives is an important measure that must be coupled with increased patient engagement, mobilization, and exercise. Use of low tidal volumes and low mean airway pressures during mechanical ventilation is helpful. A key hemodyna...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2016.01.006

    authors: Gelinas JP,Walley KR

    更新日期:2016-06-01 00:00:00

  • Pulmonary function testing in children.

    abstract::This article concentrates on those factors that are particularly important for performing and interpreting lung function tests in children. Specifically, technical considerations such as equipment, personnel, test performance, and bronchoprovocation procedures are discussed. Changes in lung function with growth and ap...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Eisenberg JD,Wall MA

    更新日期:1987-12-01 00:00:00

  • Thoracic Manifestations of Rheumatoid Arthritis.

    abstract::Rheumatoid arthritis (RA) is commonly associated with pulmonary disease that can affect any anatomic compartment of the thorax. The most common intrathoracic manifestations of RA include interstitial lung disease, airway disease, pleural disease, rheumatoid nodules, and drug-induced toxicity. Patients with RA with tho...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2019.05.003

    authors: Esposito AJ,Chu SG,Madan R,Doyle TJ,Dellaripa PF

    更新日期:2019-09-01 00:00:00

  • Mycobacterium avium complex pulmonary disease in patients with pre-existing lung disease.

    abstract::Patients with MAC-PD and pre-existing lung disease are a distinct group from the more common and recently recognized group of predominantly middle- to older-aged women without pre-existing lung disease. Those with pre-existing disease are expected to have more sputum positivity and slower conversion of sputum with tre...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(02)00022-9

    authors: Aksamit TR

    更新日期:2002-09-01 00:00:00

  • Approach to adult respiratory distress syndrome and respiratory failure in elderly patients.

    abstract::Because of physiologic changes associated with aging and the development of chronic illness, the elderly will continue to be at risk for catastrophic illnesses including adult respiratory distress syndrome (ARDS). Current management of elderly patients with ARDS is only supportive and focused on avoiding complications...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Griffith D,Idell S

    更新日期:1993-09-01 00:00:00

  • Master Clinician and Public Health Practitioner: Selected Occupational and Environmental Pulmonary Cases.

    abstract::Occupational and environmental exposures contribute to the development and progression of most lung diseases, yet their impact is greatly under-recognized in clinical practice. Clinicians caring for patients with respiratory diseases should maintain a high index of suspicion for occupational and environmental contribu...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2020.08.019

    authors: James E,Linde B,Redlich CA

    更新日期:2020-12-01 00:00:00

  • Respiratory disability. The uncoupling of oxygen consumption and disability.

    abstract::In the past it was believed that respiratory disability could be objectively assessed by comparing the measured O2 consumption requirement of the job with the subjects' measured or estimated maximal oxygen consumption. More recently, it has become clear that this "classic" paradigm does not completely apply to all sit...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Harber P

    更新日期:1992-06-01 00:00:00

  • Diagnosis of roentgenographically occult lung cancer by sputum cytology.

    abstract::The specialty has the knowledge and technology to change the outcome of lung cancer. Lung cancer, diagnosed in early stages, is as curable as all other cancers. Sputum cytology is the initial step in diagnosing roentgenographically occult lung cancer. Sputum cytology is complementary to CT scanning. Sputum cytology id...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(03)00060-1

    authors: Petty TL,Tockman MS,Palcic B

    更新日期:2002-03-01 00:00:00

  • Cognitive impairment in the intensive care unit.

    abstract::Delirium is a frequent complication in older patients in the ICU and often persists beyond their ICU stay. Delirium in older persons in the ICU is a dynamic and complex process. There is a high prevalence of pre-existing cognitive impairment in patients who are admitted to the medical ICU. This pre-existing cognitive ...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(03)00092-3

    authors: Pisani MA,McNicoll L,Inouye SK

    更新日期:2003-12-01 00:00:00

  • Therapy for stage I and stage II non-small cell lung cancer.

    abstract::Despite complete resection of what seems to be all evident tumor, one third to three quarters of patients with stages I and II NSCLC ultimately succumb to this neoplasm. Patients who are cured of an original NSCLC or small cell cancer remain at risk for a new primary lung cancer. Although the importance of lifelong su...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(03)00067-4

    authors: Tanoue LT,Ponn RB

    更新日期:2002-03-01 00:00:00

  • Cough: differential diagnosis and treatment.

    abstract::Cough is a complex physiologic event that protects the lungs from mechanical, chemical, and thermal injury. It is a normal reflex and therefore helps humans to adapt to an ever-changing environment. Cough can also be a pathologic reflex in that it may be an important and often the only sign of serious disease, may sig...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Braman SS,Corrao WM

    更新日期:1987-06-01 00:00:00

  • Chemotherapy and radiation for the treatment of non-small-cell lung cancer. A critical review.

    abstract::Lung cancer remains the most common fatal malignancy, so even modest therapeutic advances are potentially beneficial to large numbers of patients. For patients with regional nodal metastases identified at thoracotomy, adjuvant chemotherapy may be of benefit and additional clinical trials are in progress. Locally advan...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Murren JR,Buzaid AC

    更新日期:1993-03-01 00:00:00

  • Cytomegalovirus infection.

    abstract::The pathogenic importance of cytomegalovirus (CMV) infection in AIDS-associated pneumonitis is controversial. Uncertainty regarding the significance of CMV isolation from pulmonary secretions of AIDS patients results in part from the difficulty in distinguishing CMV infection from CMV disease and from the high frequen...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Jacobson MA,Mills J

    更新日期:1988-09-01 00:00:00

  • How to implement an asthma education program.

    abstract::Given that poor asthma management leads to such devastating rates of morbidity and mortality in this country, efforts must be made to increase the knowledge, skills, and behaviors of persons with asthma. The suggestions and recommendations provided here represent a blend of academic opinion and practical advice on met...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Kohler CL,Davies SL,Bailey WC

    更新日期:1995-12-01 00:00:00

  • CT and MR in pleural disease.

    abstract::A number of different imaging modalities can be used in the assessment of pleural disease. Although ultrasound has been the more traditional method, CT has found increasing utility for the assessment of the empyema and loculated pleural fluid collections prior to drainage and the evaluation of benign and malignant ple...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(05)70076-9

    authors: McLoud TC

    更新日期:1998-06-01 00:00:00

  • The cost of lung transplantation and the quality of life post-transplant.

    abstract::As recently as the 1992 Report of the American Thoracic Society Workshop on Lung Transplantation, no QOL facts were given and no knowledge gaps related to QOL outcomes were cited. Even at the present time, the information in that area is based on a relatively small set of preliminary reports. Current information indic...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(05)70387-7

    authors: Gross CR,Raghu G

    更新日期:1997-06-01 00:00:00

  • Mechanical ventilation in an airborne epidemic.

    abstract::With the increasing threat of pandemic influenza and catastrophic bioterrorism, it is important for intensive care providers to be prepared to meet the challenge of large-scale airborne epidemics causing mass casualty respiratory failure. The severe acute respiratory syndrome outbreak exposed the vulnerability of heal...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2008.01.001

    authors: Phua GC,Govert J

    更新日期:2008-06-01 00:00:00

  • Airway stents.

    abstract::Stents are used for palliation of symptoms of central airway obstruction caused by either malignant or benign conditions. Stents may be applied for maintaining airway patency after dilatation of postinflammatory and infectious strictures, for airway dehiscence after lung transplantation, and for the management of trac...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2009.08.002

    authors: Lee P,Kupeli E,Mehta AC

    更新日期:2010-03-01 00:00:00

  • Fungal pneumonias. The endemic mycoses.

    abstract::Each year, a vast number of individuals are infected with the endemic fungi. An expanding population, along with further land development in endemic areas, will likely continue to place individuals at risk for exposure to these organisms. A high index of suspicion may be required to diagnose histoplasmosis, blastomyco...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0272-5231(05)70232-x

    authors: Goldman M,Johnson PC,Sarosi GA

    更新日期:1999-09-01 00:00:00

  • Extrapulmonary tuberculosis in high prevalence of tuberculosis and low prevalence of HIV.

    abstract::The authors' data show a higher rate of pleural and meningeal involvement among extrapulmonary TB cases than expected by previous works. Special attention should be given to tuberculous meningitis cases among all extrapulmonary TB cases because of its high mortality rate. The most common extrapulmonary involvement is ...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章

    doi:10.1016/s0272-5231(02)00002-3

    authors: Ozbay B,Uzun K

    更新日期:2002-06-01 00:00:00

  • Pulmonary Limitations in Heart Failure.

    abstract::The heart and lungs are intimately linked. Hence, impaired function of one organ may lead to changes in the other. Accordingly, heart failure is associated with airway obstruction, loss of lung volume, impaired gas exchange, and abnormal ventilatory control. Cardiopulmonary exercise testing is an excellent tool for ev...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2019.02.010

    authors: Cundrle I Jr,Olson LJ,Johnson BD

    更新日期:2019-06-01 00:00:00

  • Physiological effects of diaphragm muscle denervation and disuse.

    abstract::From our studies, it is clear that diaphragm muscle neuromotor control is responsive to alterations in innervation and activation. These adaptations to altered use appear to be most pronounced among fast-twitch motor units composed of type II muscle fibers. Because the plasticity involves diminished contractile streng...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Sieck GC

    更新日期:1994-12-01 00:00:00

  • Chronic thromboembolic pulmonary hypertension.

    abstract::Chronic thromboembolic pulmonary hypertension is one of the few forms of pulmonary hypertension that is surgically curable. It is likely underdiagnosed and must be considered in every patient presenting with pulmonary hypertension to avoid missing the opportunity to cure these patients. This article discusses the epid...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2010.07.006

    authors: Auger WR,Kim NH,Trow TK

    更新日期:2010-12-01 00:00:00

  • Management of Low-Risk Pulmonary Embolism.

    abstract::Pulmonary embolism remains a leading cause of morbidity and mortality in the United States. However, with improved recognition and diagnosis, the risk of death diminishes. The diagnosis depends on the clinician's suspicion. Pulmonary emboli are categorized into low, intermediate, or high risk based on the scoring scal...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2018.04.013

    authors: Islam EA,Winn RE,Test V

    更新日期:2018-09-01 00:00:00

  • Computed tomography of asbestos-related pulmonary parenchymal and pleural diseases.

    abstract::Computed tomography has acquired an increasingly central role in the evaluation of asbestos-exposed individuals. The advantages of increased contrast resolution and axial image display have extended our ability to interrogate areas of the pulmonary parenchyma and pleura that are inadequately seen on chest radiographs....

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Aberle DR,Balmes JR

    更新日期:1991-03-01 00:00:00

  • Evaluation of daytime sleepiness.

    abstract::In summary, the evaluation of the tired patient requires an awareness of the various meanings of tiredness. Furthermore, it is important to differentiate normal sleepiness that is a product of circadian rhythm variation in vigilance from pathologic sleepiness. Sleepiness that results from faulty habits, e.g., altered ...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Moldofsky H

    更新日期:1992-09-01 00:00:00

  • Viral Pneumonia in Patients with Hematopoietic Cell Transplantation and Hematologic Malignancies.

    abstract::Viral pneumonia is a common complication for patients with hematologic malignancies and after hematopoietic cell transplantation causing significant morbidity, and often mortality. Infections are predominantly caused by herpes viruses, either by reactivation of latent infection, or less commonly primary infection, or ...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2016.12.009

    authors: Green ML

    更新日期:2017-06-01 00:00:00

  • The treatment of rapidly growing mycobacterial infections.

    abstract::Rapidly growing mycobacteria (RGM) include a diverse group of species. We address the treatment of the most commonly isolated RGM-M abscessus complex, M fortuitum, and M chelonae. The M abscessus complex is composed of 3 closely related species: M abscessus senso stricto (hereafter M abscessus), M massiliense, and M b...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2014.10.004

    authors: Kasperbauer SH,De Groote MA

    更新日期:2015-03-01 00:00:00

  • Imaging of small airways disease and chronic obstructive pulmonary disease.

    abstract::CT is a useful tool for identification of small airways diseases, and it can be used to classify these entities into inflammatory and constrictive bronchiolitis. Inflammatory forms of bronchiolitis include cellular bronchiolitis (usually caused by infection or aspiration), respiratory bronchiolitis, panbronchiolitis, ...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2007.11.008

    authors: Lynch DA

    更新日期:2008-03-01 00:00:00

  • Preinvasive lesions of the bronchus.

    abstract::It has been proposed that invasive carcinoma of the bronchus develops through a transition from preinvasive lesions to overt malignancy. Newer diagnostic technologies have provided a more sensitive way to diagnose preinvasive lesions and a better understanding of the prevalence of such lesions. The natural history of ...

    journal_title:Clinics in chest medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ccm.2011.08.008

    authors: Rivera MP

    更新日期:2011-12-01 00:00:00