Chronic thromboembolic pulmonary hypertension.

abstract：:The tuberculosis (TB) epidemic is well controlled in most developed countries and the focus in these areas has shifted to TB eradication. Transmission within nonendemic areas is limited and most cases of TB result from reactivation of distant (latent) infection. With adequate resources, wide-scale use of preventive th...

journal_title：Clinics in chest medicine

authors： Marais BJ,Ayles H,Graham SM,Godfrey-Faussett P

更新日期：2009-12-01 00:00:00

abstract：:Many different therapeutic compounds are associated with pulmonary toxicity. Although the mechanism of injury for many of these compounds is poorly defined, several compounds are believed to produce alterations in normal lung biochemistry. These mechanisms of injury in both clinical and experimental models are discuss...

journal_title：Clinics in chest medicine

authors： Duncan CA

更新日期：1989-03-01 00:00:00

abstract：:Pathologic conditions affecting the abdomen are a significant cause of morbidity and mortality in the intensive care unit, but their importance is not widely recognized. This article presents several aspects of abdominal pathology that can occur in intensive care unit patients. This pathology may have a considerable i...

journal_title：Clinics in chest medicine

authors： Liolios A,Oropello JM,Benjamin E

更新日期：1999-06-01 00:00:00

abstract：:Patients with MAC-PD and pre-existing lung disease are a distinct group from the more common and recently recognized group of predominantly middle- to older-aged women without pre-existing lung disease. Those with pre-existing disease are expected to have more sputum positivity and slower conversion of sputum with tre...

journal_title：Clinics in chest medicine

authors： Aksamit TR

更新日期：2002-09-01 00:00:00

abstract：:Biologic drugs have revolutionized the treatment of certain hematologic, autoimmune, and malignant diseases, but they may place patients at risk for reactivation or acquisition of tuberculosis. This risk is highest with the tumor necrosis factor-alpha (TNF-α) inhibitors. Amongst this class of drugs, the monoclonal ant...

journal_title：Clinics in chest medicine

authors： Godfrey MS,Friedman LN

更新日期：2019-12-01 00:00:00

abstract：:The Early Goal-Directed Therapy versus Standard Care for Sepsis trial by Rivers and colleagues in 2001 suggested that a significant mortality reduction may be realized through goal-directed interventions early in the care of patients with septic shock. However, the recent publication of the Protocol-Based Care for Ear...

journal_title：Clinics in chest medicine

authors： Henning DJ,Shapiro NI

更新日期：2016-06-01 00:00:00

abstract：:Bacterial pneumonias occur with increased frequency and can be associated with increased morbidity in the HIV-infected population compared with normals. The pathogens that most frequently cause community-acquired pneumonias are S. pneumoniae, H. influenzae, and occasionally S. aureus. These pneumonias usually respond ...

journal_title：Clinics in chest medicine

authors： Fels AO

更新日期：1988-09-01 00:00:00

abstract：:Hypersensitivity pneumonitis (HP) represents a group of immunologically mediated lung disorders provoked by recurrent exposure to various environmental agents. HP is multifaceted and may mimic almost any interstitial lung disease, some infectious diseases,and even bronchiolar disorders. In the absence of a diagnostic ...

journal_title：Clinics in chest medicine

authors： Selman M

更新日期：2004-09-01 00:00:00

abstract：:This article concentrates on those factors that are particularly important for performing and interpreting lung function tests in children. Specifically, technical considerations such as equipment, personnel, test performance, and bronchoprovocation procedures are discussed. Changes in lung function with growth and ap...

journal_title：Clinics in chest medicine

authors： Eisenberg JD,Wall MA

更新日期：1987-12-01 00:00:00

abstract：:The synthesis of nitric oxide (NO) and its targets are reviewed physiologically during sepsis and wound healing, a self-limiting process in which mechanisms are still identified incompletely. NO also plays an active and direct role during infection, aimed at protecting the host and destroying the microbe. During septi...

journal_title：Clinics in chest medicine

authors： Payen D,Bernard C,Beloucif S

更新日期：1996-06-01 00:00:00

abstract：:Each year, a vast number of individuals are infected with the endemic fungi. An expanding population, along with further land development in endemic areas, will likely continue to place individuals at risk for exposure to these organisms. A high index of suspicion may be required to diagnose histoplasmosis, blastomyco...

journal_title：Clinics in chest medicine

authors： Goldman M,Johnson PC,Sarosi GA

更新日期：1999-09-01 00:00:00

abstract：:Prophylaxis for DVT unequivocally is beneficial in patients identified to be at high risk. Heparin prophylaxis with subcutaneous low-dose UFH is adequate in some clinical settings but less effective in others. LMWH preparations are effective and safe as prophylaxis in certain medical patients as well as in general sur...

journal_title：Clinics in chest medicine

authors： Tapson VF,Hull RD

更新日期：1995-06-01 00:00:00

abstract：:In the past 3 years, lung volume reduction surgery has become the most controversial topic in the clinical management of patients with emphysema. Although literature has added to the understanding of the procedure, many important issues remain unclear. This article emphasizes functional and basic physiologic changes t...

journal_title：Clinics in chest medicine

authors： Sciurba FC

更新日期：1997-06-01 00:00:00

abstract：:The types of pulmonary arterial hypertension described here all focus attention on the changes produced in the lung's microcirculation, particularly the precapillary unit. Although one senses intuitively that obliteration of resistance arteries is an effective cause of hypertension, we emphasize that cell metaplasia a...

journal_title：Clinics in chest medicine

authors： Meyrick B,Reid L

更新日期：1983-05-01 00:00:00

abstract：:Our understanding of chronic bronchitis has been hampered by the fact that the diagnosis is based upon historical evidence of recurrent cough and sputum without any requirement that certain physiologic or microscopic criteria be met. Despite the fact that epidemiological studies have implicated viruses, bacteria, and ...

journal_title：Clinics in chest medicine

authors： Sachs FL

更新日期：1981-01-01 00:00:00

abstract：:Elevated serum IgE has many etiologies including parasitic infection, allergy and asthma, malignancy, and immune dysregulation. The hyper-IgE syndromes caused by mutations in STAT3, DOCK8, and PGM3 are monogenic primary immunodeficiencies associated with high IgE, eczema, and recurrent infections. These primary immuno...

journal_title：Clinics in chest medicine

authors： Freeman AF,Olivier KN

更新日期：2016-09-01 00:00:00

abstract：:Pneumonia is an important cause of morbidity and mortality. However, pneumonia is an unusual outcome of respiratory infection. Most of the time, microbes in the lung can be controlled by a combination of constitutive and recruited defense mechanisms. Inflammation is a key component of recruited defenses. Variations in...

journal_title：Clinics in chest medicine

authors： Mizgerd JP

更新日期：2018-12-01 00:00:00

abstract：:CT is a useful tool for identification of small airways diseases, and it can be used to classify these entities into inflammatory and constrictive bronchiolitis. Inflammatory forms of bronchiolitis include cellular bronchiolitis (usually caused by infection or aspiration), respiratory bronchiolitis, panbronchiolitis, ...

journal_title：Clinics in chest medicine

authors： Lynch DA

更新日期：2008-03-01 00:00:00

abstract：:After half a century of clinical experience and research, management of pulmonary arterial hypertension remains a challenge. Currently, data to support the use of standard therapies for pulmonary arterial hypertension (oxygen supplementation, diuretics, digoxin, anticoagulation, and calcium channel blockers) are mostl...

journal_title：Clinics in chest medicine

authors： Alam S,Palevsky HI

更新日期：2007-03-01 00:00:00

abstract：:Despite complete resection of what seems to be all evident tumor, one third to three quarters of patients with stages I and II NSCLC ultimately succumb to this neoplasm. Patients who are cured of an original NSCLC or small cell cancer remain at risk for a new primary lung cancer. Although the importance of lifelong su...

journal_title：Clinics in chest medicine

authors： Tanoue LT,Ponn RB

更新日期：2002-03-01 00:00:00

abstract：:Primary graft dysfunction (PGD) is the most important cause of early morbidity and mortality following lung transplantation. PGD affects up to 25% of all lung transplant procedures and currently has no proven preventive therapy. Lung transplant recipients who recover from PGD may have impaired long-term function and a...

journal_title：Clinics in chest medicine

authors： Lee JC,Christie JD

更新日期：2011-06-01 00:00:00

abstract：:The authors' data show a higher rate of pleural and meningeal involvement among extrapulmonary TB cases than expected by previous works. Special attention should be given to tuberculous meningitis cases among all extrapulmonary TB cases because of its high mortality rate. The most common extrapulmonary involvement is ...

journal_title：Clinics in chest medicine

authors： Ozbay B,Uzun K

更新日期：2002-06-01 00:00:00

abstract：:An older smoker tends to be asked less often to quit although he or she has much to gain from achieving a nonsmoking status. Multiple barriers may interfere with attempting to quit including nicotine withdrawal, doubted self-efficacy, other smokers in one's environment, or misperceptions of little gain from quitting. ...

journal_title：Clinics in chest medicine

authors： Cox JL

更新日期：1993-09-01 00:00:00

abstract：:Respiratory viruses are common in solid organ and hematopoietic stem cell transplant recipients and a recognized cause of significant morbidity and mortality. Epidemiology, risk factors, and attributable mortality in both populations are reviewed. In addition, virus-specific prevention and treatment options, including...

journal_title：Clinics in chest medicine

authors： Paulsen GC,Danziger-Isakov L

更新日期：2017-12-01 00:00:00

abstract：:This article reviews aspects of mechanical ventilation in patients without lung injury, patients in the perioperative period, and those with neurologic injury or disease including spinal cord injury. Specific emphasis is placed on ventilator strategies, including timing and indications for tracheostomy. Lung protectiv...

journal_title：Clinics in chest medicine

authors： Bowton DL,Scott LK

更新日期：2016-12-01 00:00:00

abstract：:Interventional pulmonology encompasses diagnostic and therapeutic bronchoscopic procedures, and pleural interventions. In the last 10 years older techniques have been refined and exciting new technologies have extended the reach and application of the instruments used. The main areas within pulmonary medicine for whic...

journal_title：Clinics in chest medicine

authors： Morgan RK,Ernst A

更新日期：2011-03-01 00:00:00

abstract：:Flexible fiberoptic bronchoscopy is the most useful invasive technique for diagnosing lung cancer. This article details the use and efficacy of bronchoscopy with such established techniques as forceps biopsy, brush biopsy, and bronchial washing in the diagnosis and staging of bronchoscopically visible central lung can...

journal_title：Clinics in chest medicine

authors： Arroliga AC,Matthay RA

更新日期：1993-03-01 00:00:00

abstract：:The pathogenesis of O2 toxicity involves intracellular production of partially reduced O2 metabolites, which increases with O2 partial pressure. Cytotoxic O2 metabolites impair enzyme function and inhibit DNA, protein, and surfactant lipid biosynthesis. Compounds used clinically that increase O2 metabolism or that are...

journal_title：Clinics in chest medicine

authors： Jackson RM

更新日期：1990-03-01 00:00:00

abstract：:Cough is a complex physiologic event that protects the lungs from mechanical, chemical, and thermal injury. It is a normal reflex and therefore helps humans to adapt to an ever-changing environment. Cough can also be a pathologic reflex in that it may be an important and often the only sign of serious disease, may sig...

journal_title：Clinics in chest medicine

authors： Braman SS,Corrao WM

更新日期：1987-06-01 00:00:00

abstract：:Nonresolving pneumonia is a common and frequently misunderstood problem faced by the practicing pulmonologist. While radiographic resolution of most infections is relatively long and lags behind clinical signs of recovery, data suggest that a variety of host defense problems are a consequence of systemic illness and a...

journal_title：Clinics in chest medicine

authors： Fein AM,Feinsilver SH,Niederman MS,Fiel S,Pai PB

更新日期：1987-09-01 00:00:00