Medications for obesity: mechanisms and applications.

abstract：:Non-small cell lung cancer with very limited extent of metastatic spread commonly is termed, oligometastatic disease (OMD), and typically described as no more than 3 to 5 lesions. Definitive local therapy potentially leads to significant improvement in progression-free survival and overall survival. OMD may occur de n...

journal_title：Clinics in chest medicine

authors： West H

更新日期：2020-06-01 00:00:00

abstract：:Pulmonary complications occur in 40% to 60% of recipients of bone marrow trans-plants, account for more than 90% of mortality, and develop during identifiable phases. Phase 1 (Days 1-30) includes pulmonary edema; diffuse alveolar hemorrhage; and various bacterial, fungal, and viral infections; Phase 2 (Days 31-100) us...

journal_title：Clinics in chest medicine

authors： Yen KT,Lee AS,Krowka MJ,Burger CD

更新日期：2004-03-01 00:00:00

abstract：:Sarcoidosis is a systemic disease with a favorable prognosis, high remission rate, and low mortality. Cardiac involvement alters this prognosis. Clinical manifestations most commonly include arrhythmias, conduction abnormalities, and congestive heart failure. Treatment includes immunosuppressant therapy, permanent pac...

journal_title：Clinics in chest medicine

authors： Ayyala US,Nair AP,Padilla ML

更新日期：2008-09-01 00:00:00

abstract：:This article reviews aspects of mechanical ventilation in patients without lung injury, patients in the perioperative period, and those with neurologic injury or disease including spinal cord injury. Specific emphasis is placed on ventilator strategies, including timing and indications for tracheostomy. Lung protectiv...

journal_title：Clinics in chest medicine

authors： Bowton DL,Scott LK

更新日期：2016-12-01 00:00:00

abstract：:Chronic thromboembolic pulmonary hypertension is one of the few forms of pulmonary hypertension that is surgically curable. It is likely underdiagnosed and must be considered in every patient presenting with pulmonary hypertension to avoid missing the opportunity to cure these patients. This article discusses the epid...

journal_title：Clinics in chest medicine

authors： Auger WR,Kim NH,Trow TK

更新日期：2010-12-01 00:00:00

abstract：:This article reviews the basic pathophysiologic mechanisms underlying the abnormal pulmonary gas exchange often seen in patients with cirrhosis. To summarize, the following keypoints seem appropriate: (1) Patients with cirrhosis have a low pulmonary vascular tone characterized by a poor or absent hypoxic pressor respo...

journal_title：Clinics in chest medicine

authors： Agusti AG,Roca J,Rodriguez-Roisin R

更新日期：1996-03-01 00:00:00

abstract：:Interventional pulmonology encompasses diagnostic and therapeutic bronchoscopic procedures, and pleural interventions. In the last 10 years older techniques have been refined and exciting new technologies have extended the reach and application of the instruments used. The main areas within pulmonary medicine for whic...

journal_title：Clinics in chest medicine

authors： Morgan RK,Ernst A

更新日期：2011-03-01 00:00:00

abstract：:Our ability to define appropriate molecular targets for preclinical development and develop better methods needs to be improved, to determine the clinical value of novel acute respiratory distress syndrome (ARDS) agents. Clinical trials must have realistic sample sizes and meaningful end points and use the available o...

journal_title：Clinics in chest medicine

authors： Curley GF,McAuley DF

更新日期：2014-12-01 00:00:00

abstract：:Massive hemoptysis is a rare, but life-threatening event. Death from massive hemoptysis is usually due to aspiration of blood. Thus, the initial evaluation should occur simultaneously with efforts to control the patient's airway and respiratory status. Therapeutic interventions can be directed with an understanding of...

journal_title：Clinics in chest medicine

authors： Thompson AB,Teschler H,Rennard SI

更新日期：1992-03-01 00:00:00

abstract：:The hyperventilation seen in asthma is due to an increase in respiratory drive. This may be reflected by increased neural output to the respiratory muscles and probably by alterations in the respiratory pattern. This increased respiratory drive is most likely in response to irritant receptor stimulation in the lung. O...

journal_title：Clinics in chest medicine

authors： Schiff M

更新日期：1980-01-01 00:00:00

abstract：:Available data show that Africa, together with the Americas and western and central Europe, reported the lowest prevalence of multidrug-resistant tuberculosis (MDR-TB). However, sub-Saharan Africa has a high TB incidence and the highest human immunodeficiency virus (HIV) prevalence in the world, and because of the hig...

journal_title：Clinics in chest medicine

authors： Schaaf HS,Moll AP,Dheda K

更新日期：2009-12-01 00:00:00

abstract：:Two recent major guidelines on diagnosis and treatment of ventilator-associated pneumonia (VAP) recommend consideration of local antibiotic resistance patterns and individual patient risks for resistant pathogens when formulating an initial empiric antibiotic regimen. One recommends against invasive diagnostic techniq...

journal_title：Clinics in chest medicine

authors： Metersky ML,Kalil AC

更新日期：2018-12-01 00:00:00

abstract：:Obesity is a major risk factor for asthma. This association appears related to altered dietary composition and metabolic factors that can directly affect airway reactivity and airway inflammation. This article discusses how specific changes in the western diet and metabolic changes associated with the obese state affe...

journal_title：Clinics in chest medicine

authors： Dixon AE,Holguin F

更新日期：2019-03-01 00:00:00

abstract：:For clinicians involved in airway management, a plan of action for dealing with the difficult airway or a failed intubation should be developed well in advance of encountering a patient in whom intubation is not routine. When difficulty is anticipated, the equipment necessary for performing a difficult intubation shou...

journal_title：Clinics in chest medicine

authors： Schwartz DE,Wiener-Kronish JP

更新日期：1991-09-01 00:00:00

abstract：UNLABELLED:VAP is a complex nosocomial infection, the disease expression and resulting patient outcome of which is dependent on host factors, the causative organism, the timing and adequacy of treatment, and the presence of intrinsic or inducible antibiotic resistance. Significant improvements have been achieved in our...

journal_title：Clinics in chest medicine

authors： Kollef MH

更新日期：1999-09-01 00:00:00

abstract：:ICU-acquired weakness is a common problem and carries significant morbidity. Despite evidence that early mobility can mitigate this, implementation outside of the research setting is lagging. Understanding barriers at the systems as well as individual level is a crucial step in successful implementation of an ICU mobi...

journal_title：Clinics in chest medicine

authors： Honiden S,Connors GR

更新日期：2015-09-01 00:00:00

abstract：:In summary, long-term complications of artificial airways are rare but important sequelae of artificial airways. Many of the potential long-term complications of translaryngeal intubation and tracheotomy are similar and overlapping. Although most patients who undergo these procedures tend to tolerate them without diff...

journal_title：Clinics in chest medicine

authors： Sue RD,Susanto I

更新日期：2003-09-01 00:00:00

abstract：:Primary graft dysfunction (PGD) is the most important cause of early morbidity and mortality following lung transplantation. PGD affects up to 25% of all lung transplant procedures and currently has no proven preventive therapy. Lung transplant recipients who recover from PGD may have impaired long-term function and a...

journal_title：Clinics in chest medicine

authors： Lee JC,Christie JD

更新日期：2011-06-01 00:00:00

abstract：:A comprehensive assessment is the foundation of a successful pulmonary rehabilitation programme. There is a broad selection of outcome measures that tend to be categorized into measures of exercise performance (including measures of strength) quality of life (health status), psychological well-being, nutritional statu...

journal_title：Clinics in chest medicine

authors： Singh S

更新日期：2014-06-01 00:00:00

abstract：:The heart and lungs are intimately linked. Hence, impaired function of one organ may lead to changes in the other. Accordingly, heart failure is associated with airway obstruction, loss of lung volume, impaired gas exchange, and abnormal ventilatory control. Cardiopulmonary exercise testing is an excellent tool for ev...

journal_title：Clinics in chest medicine

authors： Cundrle I Jr,Olson LJ,Johnson BD

更新日期：2019-06-01 00:00:00

abstract：:Recent events have underscored the importance of proper diagnosis and management of patients with inhalation injury. Clinicians who care for individuals who have sustained inhalation damage to their respiratory tract need to take a careful exposure history and be alert to possibilities of delayed effects and clinical ...

journal_title：Clinics in chest medicine

authors： Rabinowitz PM,Siegel MD

更新日期：2002-12-01 00:00:00

abstract：:Most gravidas with asthma can be managed with an inhaled beta-adrenergic agonist (terbutaline or epinephrine) and beclomethasone dipropionate. The administration of prednisone to control exacerbation of asthma is appropriate and should not be withheld if current medications are inadequate. The outcome of pregnancy in ...

journal_title：Clinics in chest medicine

authors： Greenberger PA

更新日期：1992-12-01 00:00:00

abstract：:Sjögren's syndrome is one of the most common systemic rheumatic diseases. Pulmonary disease is prevalent in Sjögren's syndrome; respiratory manifestations include chronic cough, obstructive airways disease, pulmonary lymphoma, and interstitial lung disease that may progress to severe pulmonary fibrosis. ...

journal_title：Clinics in chest medicine

authors： Cain HC,Noble PW,Matthay RA

更新日期：1998-12-01 00:00:00

abstract：:Given that poor asthma management leads to such devastating rates of morbidity and mortality in this country, efforts must be made to increase the knowledge, skills, and behaviors of persons with asthma. The suggestions and recommendations provided here represent a blend of academic opinion and practical advice on met...

journal_title：Clinics in chest medicine

authors： Kohler CL,Davies SL,Bailey WC

更新日期：1995-12-01 00:00:00

abstract：:Chronic lung diseases, including chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH), are unusually prevalent among persons infected with human immunodeficiency virus (HIV). Often these disease states are identified at younger ages than would be expected in the general population. Recent epide...

journal_title：Clinics in chest medicine

authors： Fitzpatrick M,Crothers K,Morris A

更新日期：2013-06-01 00:00:00

abstract：:Gas exchange between the atmosphere and the human body depends on the lungs and the function of the respiratory pump. The respiratory pump consists of the respiratory control center located in the brain, bony rib cage, diaphragm, and intercostal, accessory, and abdominal muscles. A variety of muscles serve to fine-tun...

journal_title：Clinics in chest medicine

authors： Benditt JO

更新日期：2018-06-01 00:00:00

abstract：:Massive hemoptysis accounts for a minority of all patients with hemoptysis but poses a major challenge for the acute and long-term treatment. Massive hemoptysis can lead to asphyxiation and airway obstruction, shock, and exsanguination. Bronchoscopy plays an integral part in managing massive hemoptysis in diagnosis an...

journal_title：Clinics in chest medicine

authors： Dweik RA,Stoller JK

更新日期：1999-03-01 00:00:00

abstract：:This article concentrates on those factors that are particularly important for performing and interpreting lung function tests in children. Specifically, technical considerations such as equipment, personnel, test performance, and bronchoprovocation procedures are discussed. Changes in lung function with growth and ap...

journal_title：Clinics in chest medicine

authors： Eisenberg JD,Wall MA

更新日期：1987-12-01 00:00:00

abstract：:Pulmonary thromboembolism is a major cause of maternal mortality. DVT causes significant morbidity in pregnancy and in later life owing to the post-thrombotic syndrome. Obstetricians must have an understanding of the risk factors for VTE, the appropriate use of prophylaxis, the need for objective diagnosis in women wi...

journal_title：Clinics in chest medicine

authors： Greer IA

更新日期：2003-03-01 00:00:00

abstract：:Since last reviewed in this forum, there have been remarkable advances in our understanding of the acute inflammatory process and how it contributes to the development of ALI. As stated in the beginning of this article, it is not possible to even begin to review all the specific advances that have been made. Instead, ...

journal_title：Clinics in chest medicine

authors： Parsons PE

更新日期：2000-09-01 00:00:00