Renal giant cytoplasmic inclusions in Chédiak-Higashi syndrome: first ultrastructural demonstration in a human biopsy.

Abstract:

:This report ultrastructurally illustrates the giant lysosome-related organelles in the various cellular components of a renal biopsy from a 10 year-old female affected by the Chédiak-Higashi syndrome. Albeit similar observations have been made and reported in animal models of the syndrome, to the author's knowledge, this is the first illustration of the changes as demonstrated in a human renal biopsy.

journal_name

Ultrastruct Pathol

authors

de Chadarévian JP

doi

10.3109/01913123.2011.584656

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

172-5

issue

4

eissn

0191-3123

issn

1521-0758

journal_volume

35

pub_type

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