The ultrastructure of hybrid acute leukemia: a study of 15 cases.

Abstract:

:The objective of this study was to investigate the ultrastructural characteristics of hybrid acute leukemia (HAL). Fifteen cases of HAL were studied by transmission electron microscopy (TEM), focusing on organelles and myeloperoxidase (MPO) reaction of leukemic cells. By TEM, 5 out 15 cases of HAL were consistent with immunophenotyping (3 cases of biphenotypic type, and 2 cases of biclonal type with granulocytes and lymphocytes); 2 cases were suspected as HAL. On other hand, 5 cases of HAL were assigned to ALL, and 2 cases were misinterpreted as M5a and 1 as M4b. Most of the blast cells of biphenotypic HAL showed lymphoid features, except some cases containing MPO positive granules in blasts, while a few cases exhibited monocytic or nonspecific features. TEM offers advantages in the diagnosis of biclonal type HAL and biphenotypic HAL positive for MPO. However, it is difficult to differentiate MPO-negative cases of biphenotypic HAL from ALL and a few cases may be misinterpreted as M5 by TEM.

journal_name

Ultrastruct Pathol

authors

Ru YX,Wang HJ,Yang BX,Liu JH,Li ZQ,Li CW,Wang JX,Mi YC

doi

10.1080/019131290968722

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

341-7

issue

5

eissn

0191-3123

issn

1521-0758

pii

JH0551V0X1585361

journal_volume

29

pub_type

杂志文章
  • Ultrastructural changes to rabbit fibrin and platelets due to aspartame.

    abstract::The coagulation process, including thrombin, fibrin, as well as platelets, plays an important role in hemostasis, contributing to the general well-being of humans. Fibrin formation and platelet activation are delicate processes that are under the control of many small physiological events. Any one of these many proces...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120701376105

    authors: Pretorius E,Humphries P

    更新日期:2007-03-01 00:00:00

  • A new tool improves diagnostic test performance for transmission em evaluation of axonemal dynein arms.

    abstract::Abstract Diagnosis of primary ciliary dyskinesia (PCD) by identification of dynein arm loss in transmission electron microscopy (TEM) images can be confounded by high background noise due to random electron-dense material within the ciliary matrix, leading to diagnostic uncertainty even for experienced morphologists. ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/01913123.2013.815081

    authors: Funkhouser WK 3rd,Niethammer M,Carson JL,Burns KA,Knowles MR,Leigh MW,Zariwala MA,Funkhouser WK Jr

    更新日期:2014-08-01 00:00:00

  • Ultrastructural aspect of myocarditis: its relevance for the diagnosis.

    abstract::The Dallas consensus was used to reveal active or borderline inflammatory loci by light microscopy (LM). When lymphocyte-cardiocyte interaction was observed by electron microscopy (EM), the deleterious or dormant pattern of inflammatory process was recognized. The first was determined by lymphocytes that adhered to ca...

    journal_title:Ultrastructural pathology

    pub_type: 临床试验,杂志文章

    doi:10.3109/01913129509014620

    authors: Milin J,Stojsić D,Vucković D,Benc D,Hadzić M,Stojsić A,Zivkov-Saponja D

    更新日期:1995-11-01 00:00:00

  • Deciduoid mesothelioma: a report of 5 cases and literature review.

    abstract::Deciduoid mesothelioma was first described in young females and in the peritoneum, which led to the suggestion that deciduoid mesothelioma was a distinct subtype with specific clinical and pathologic features. Later reports, however, have shown that this type of mesothelioma may also occur in elderly people and in the...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审

    doi:10.1080/0913120290104647

    authors: Shia J,Erlandson RA,Klimstra DS

    更新日期:2002-11-01 00:00:00

  • An unusual pattern of peritubular capillary injury involving apoptosis in a renal transplant patient.

    abstract::Microvascular injury is an important factor in renal allograft survival. Repeated episodes of endothelial injury from chronic antibody-mediated rejection typically manifest at the ultrastructural level as circumferential multilayering of remodeled glomerular basement membrane material and peritubular capillary basal l...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2018.1484542

    authors: Brealey JK,Cassidy J,Manavis J

    更新日期:2018-07-01 00:00:00

  • Histological and biochemical effects of dexmedetomidine on liver during an inflammatory bowel disease.

    abstract::Inflammation in the liver is an extraintestinal manifestation that is frequently seen during inflammatory bowel diseases (IBD). The authors investigated histopathologycal, ultrastructural and antioxidant effects of dexmedetomidine (Dex) on liver during trinitrobenzene sulfonic acid (TNBS)-induced inflammatory bowel di...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2013.829150

    authors: Gul M,Kayhan B,Elbe H,Dogan Z,Otlu A

    更新日期:2015-02-01 00:00:00

  • Ameliorative effect of Pimpinella anisum oil on immunohistochemical and ultrastuctural changes of cerebellum of albino rats induced by aspartame.

    abstract::The study aims to investigate the protective effect of Pimpinella anisum oil on aspartame (ASP) which resulted in cerebellar changes. The rats were divided into four equal groups: Group 1: (control group): served as control animals. Group 2: control P. anisum oil received .5 mL/kg/d/b wt. once daily. Group 3 (ASP grou...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2014.889259

    authors: Abdul-Hamid M,Gallaly SR

    更新日期:2014-05-01 00:00:00

  • Dermal Langerhans' cell tumor in chronic myelomonocytic leukemia.

    abstract::Disseminated dermal tumors in a 71-year-old male represented the first clinical manifestation of a chronic myelomonocytic leukemia. The dermal infiltrate in one of the nodules consisted predominantly of closely packed pleomorphic Langerhans' cells (LC) with typical Birbeck granules and a strong reactivity for S-100 pr...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128809058219

    authors: Kaiserling E,Horny HP

    更新日期:1988-03-01 00:00:00

  • Tumor multiplicity is an independent prognostic factor of non-muscle-invasive bladder cancer treated with Bacillus Calmette-Guerin immunotherapy.

    abstract:BACKGROUND:Bacillus Calmette-Guerin (BCG) immunotherapy is regarded as the current treatment of choice for non muscle invasive bladder cancer (NMIBC), though its efficacy is limited by high recurrence and progression rate. Identification of factor prognosticators that might be helpful in discriminating between responde...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2012.681833

    authors: Ajili F,Manai M,Darouiche A,Chebil M,Boubaker S

    更新日期:2012-10-01 00:00:00

  • An electron microscopic study of central nervous system sarcoidosis.

    abstract::Although the fine structure of extraneural sarcoidosis is well documented, ultrastructural study of central nervous system (CNS) sarcoidosis has been limited. Electron microscopic (EM) examination of 3 biopsy cases of CNS sarcoid revealed a mixed cellular population of lymphocytes, epitheloid cells, and multinucleated...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128109048309

    authors: Trombley IK,Mirra SS,Miles ML

    更新日期:1981-07-01 00:00:00

  • Myxoid liposarcoma: study of ten cases.

    abstract::The ultrastructure of 10 myxoid liposarcomas from 9 patients is presented. Features closely resembling those of developing fetal adipose tissue were seen in all tumors. THe various cell types identified ranged from undifferentiated cells to typical multivacuolated and univacuolated lipoblasts. In addition, a secretory...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128009141413

    authors: Battifora H,Nunez-Alonso C

    更新日期:1980-04-01 00:00:00

  • The ultrastructural effects of surgical treatment of hydrosalpinx on the human endometrium: a light and electron microscopic study.

    abstract::Hydrosalpinx is a disease commonly observed in women and characterized by the obstruction which is in the shape of a fluid-filled sac at the distal part of tuba uterina closed to the ovary. In this study, we aimed to obtain endometrial tissue samples from the hydrosalpinx patients, before and after the surgical treatm...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2019.1600087

    authors: Sapmaz T,Gündoğdu LS,Çetin MT,Ürünsak IF,Polat S

    更新日期:2019-01-01 00:00:00

  • Ultrastructure of an endometrial stromal nodule with skeletal muscle.

    abstract::The ultrastructural appearance of an endometrial stromal nodule with prominent smooth and skeletal muscle differentiation is described. This is the first reported case of endometrial stromal nodule with a heterologous skeletal muscle component and emphasizes the value of electron microscopy and its correlation with im...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129309027783

    authors: Lloreta J,Prat J

    更新日期:1993-05-01 00:00:00

  • Rapid ultrasonic bath processing for electron microscopy.

    abstract::A new rapid method for the processing of biopsy specimens for electron microscopy is described. The method uses standard reagents and media and employs ultrasonic cleaning bath agitation to accelerate fluid exchange. The procedure takes approximately 2.5 h from specimen excision to polymerized block and gives excellen...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129109021307

    authors: Robb IA,Carpenter BF,Jimenez CL

    更新日期:1991-01-01 00:00:00

  • Ultrastructure of the blood and lymphatic capillaries of the respiratory tissue during inflammation and endobronchial laser therapy.

    abstract::For wide application of low-energy laser irradiation in the pulmonary clinic, study of the structural basis of the therapeutic effect is necessary. The aim of this research is to describe the structural changes of the blood and lymphatic capillaries in the respiratory tissues during inflammation and following laser bi...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120050132921

    authors: Polosukhin VV

    更新日期:2000-05-01 00:00:00

  • Detection of villous conidia of Conidiobolus coronatus in a blood sample by scanning electron microscopy investigation.

    abstract::Conidiobolus coronatus is a major insect pathogen belonging to the fungal order Entomophthorales, causing a rare subcutaneous infection of the nasofacial region, resulting in swelling of predominantly the nose, mouth, and perinasal tissue. Later in the course of the infection firm, painless, subcutaneous nodules devel...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120500482013

    authors: Hoogendijk CF,Pretorius E,Marx J,Van Heerden WE,Imhof A,Schneemann M

    更新日期:2006-01-01 00:00:00

  • The effects of X-ray irradiation on the proliferation and apoptosis of MCF-7 breast cancer cells.

    abstract::To investigate the effects of X-ray irradiation on the proliferation and apoptosis of MCF-7 breast cancer cells; MCF-7 breast cancer cells were irradiated with X-ray. After irradiation, morphological changes and growth inhibition rate of the irradiated cells were observed under an inverted microscope. 3-(4,5-dimethylt...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2013.861569

    authors: Li DL,Wei L,Wen XM,Song H,Li Q,Lv JW,Kuang CC,Wei ZZ,Zhang JW

    更新日期:2014-05-01 00:00:00

  • Ribosome-lamella complex of the lymphocytes in a case of plasmacytic lymphadenopathy with polyclonal hypergammaglobulinemia.

    abstract::A case of lymphoid hyperplasia with prominent plasmacytic proliferation histologically and with polyclonal hypergammaglobulinemia and anemia clinically was reported. This condition in a 54-year-old Japanese male was probably a type of plasma cell dyscrasia similar to a plasma cell variant of Castleman's disease. About...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128409018570

    authors: Mikata A,Suzuki S,Suzuki H,Higo O,Shimoyama M

    更新日期:1984-01-01 00:00:00

  • Jaw osteonecrosis in patients treated with bisphosphonates: an ultrastructural study.

    abstract::Osteonecrosis of the jaw is a severe bone disorder traditionally associated with periodontal disease, local malignancy, chemotherapy, glucocorticoid therapy, or trauma. Recently a growing number of publications reported the occurrence of osteonecrosis of the jaw in patients undergoing treatment with bisphosphonates. T...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913121003729806

    authors: Perrotta I,Cristofaro MG,Amantea M,Russo E,De Fazio S,Zuccalà V,Conforti F,Amorosi A,Donato G,Tripepi S,Giudice M

    更新日期:2010-08-01 00:00:00

  • Ultrastructural analysis of the oocytes of female Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) ticks subjected to the action of Azadirachta indica A. Juss (neem).

    abstract::The present study provides ultrastructural information about the acaricidal effects of neem (Azadirachta indica A. Juss) on the ovaries of R. sanguineus engorged females. In general, the main damage caused in the oocytes was alteration in the shape of the cell and of the germinal vesicle, ring-shaped nucleolus, cytopl...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2011.588819

    authors: Denardi SE,Bechara GH,de Oliveira PR,Mathias MI

    更新日期:2012-02-01 00:00:00

  • Betulinic acid induces apoptosis and ultrastructural changes in MDA-MB-231 breast cancer cells.

    abstract::The aim of this study is to investigate the effects of betulinic acid (BA) on triple-negative breast cancer MDA-MB-231 cells and observe the ultrastructural changes. The concentration of BA required to induce apoptosis in MDA-MB-231 cells has been previously reported. In this study, a cell counting kit-8 proliferation...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2017.1383548

    authors: Gao Y,Ma Q,Ma YB,Ding L,Xu XL,Wei DF,Wei L,Zhang JW

    更新日期:2018-01-01 00:00:00

  • Ultrastructural phenotype of "intestinal-type" cells in columnar-lined esophagus.

    abstract::An intestinal-type epithelium is often present at columnar-lined esophagus, gastroesophageal junction or within the so-called short segment Barrett's esophagus, but ultrastructural study failed to detect enterocytes in columnar-lined esophagus. The authors have analyzed the intestinal aspects present in areas of colum...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120252959281

    authors: Sbarbati A,Faccioli N,Ricci F,Merigo F,Benati D,Castaldini G,Cordiano C,Osculati F

    更新日期:2002-03-01 00:00:00

  • Low molecular weight proteins and the kidney: physiologic and pathologic considerations.

    abstract::Low molecular weight proteins are normally, essentially, entirely catabolized by the proximal tubules. Physiological and pathological aspects of the renal interactions of three of these proteins: light chains, B-2 microglobulin, and myoglobin share similarities, but are also unique in certain ways. In pathological con...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审

    doi:10.3109/01913129409016277

    authors: Herrera GA

    更新日期:1994-01-01 00:00:00

  • Intercellular communication by extracellular vesicles with emphasis on the roles of cordocytes in the human brain. An ultrastructural study.

    abstract::We describe in this work the presence of extracellular vesicles (EVs) along different cell types, especially cordocytes, in various clinical conditions of the human brain (atherothrombotic disease, cerebral tumors, hygroma durae matris, intracerebral cysts, Moyamoya disease and parenchymatous hematoma) using transmiss...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2014.981327

    authors: Pais V,Pais ES

    更新日期:2015-05-01 00:00:00

  • Ultrastructural investigation of lead-induced intranuclear inclusion bodies in mice.

    abstract::By means of optical and electron microscopy and by atomic absorption spectrophotometry in a graphite chamber, this study evaluated the effect of temperature (22-35 degrees C) on lesions in the kidney, liver, and brain, and on concentrations of lead caused by the administration of 2 and 5 mg/kg/IP of lead acetate to Sw...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129609016324

    authors: Vicente-Ortega V,Martínez-García AF,Cremades-Campos A,Rodríguez-Vicente J,Calderón-Rubiales F,Martínez-Díaz F

    更新日期:1996-05-01 00:00:00

  • Ultrastructural localization of c-erbB-2 gene product in transitional cell carcinoma of the urinary tract.

    abstract::The c-erbB-2 gene product was demonstrated immunoelectron microscopically in human transitional cell carcinomas of the urinary tract. Two antibodies specific for the c-erbB-2 gene product were used: a polyclonal antibody directed to the intracellular domain and a monoclonal antibody recognizing an epitope in the extra...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129009007219

    authors: Moriyama M,Morishita Y,Mori S,Akiyama T,Kato T

    更新日期:1990-09-01 00:00:00

  • Ultrastructure of Developing Feline Nonciliated Bronchiolar Epithelial Cells.

    abstract::The ultrastructure of the developing bronchiolar cell was studied in six age groups: prenatal (60 d post-conception); postnatal (1-, 7-, 14- and 21-day-old); and adult. Following intratracheal fixation, the lung tissue was processed for scanning and transmission electron microscopy. The lining of terminal bronchioles ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2015.1013654

    authors: Al-Tikriti MS,Henry RW

    更新日期:2015-01-01 00:00:00

  • Monoclonal glomerulopathy with features of cryoglobulinemic glomerulopathy in murine multiple myeloma model.

    abstract::In vivo and animal models of monoclonal light chain-associated renal diseases are limited. The Vk*MYC transgenic model with multiple myeloma in 50-70 weeks old mice with renal involvement has been reported before, but detailed renal pathologic changes have not been well documented. This study fully investigated pathol...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2020.1841349

    authors: Zhang PL,Herrera GA,Liu B

    更新日期:2020-11-20 00:00:00

  • Histiocytic differentiation in acute monocytic leukemia.

    abstract::Myeloid histocytes of dendritic cells (DCs), Langerhans cells (LCs), and macrophages in varied tissues, as leukemic blasts in acute monoblastic and monocytic leukemia (AML-M5a and M5b), are derived from monocyte progenitors in bone marrow. Based on DC induction from hematopoietic stem cells, myeloid progenitors, and m...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2015.1120838

    authors: Ru YX,Dong SX,Zhao SX,Liang HY,Wang HJ,Hu X,Mi YC,Wang JX

    更新日期:2016-01-01 00:00:00

  • Ultrastructural and immunohistochemical study of epithelioid hemangioendothelioma of bone: coexpression of epithelial and endothelial markers.

    abstract::Four cases of epithelioid hemangioendothelioma of bone--a borderline malignant tumor of vascular origin--were studied ultrastructurally and immunohistochemically. The epithelioid tumor cells were positive for vimentin, polyclonal and monoclonal cytokeratins, and the endothelial markers factor VIII-related antigen (FVI...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:

    authors: van Haelst UJ,Pruszczynski M,ten Cate LN,Mravunac M

    更新日期:1990-03-01 00:00:00