Abstract:
:The objective of this study was to investigate the ultrastructural characteristics of hybrid acute leukemia (HAL). Fifteen cases of HAL were studied by transmission electron microscopy (TEM), focusing on organelles and myeloperoxidase (MPO) reaction of leukemic cells. By TEM, 5 out 15 cases of HAL were consistent with immunophenotyping (3 cases of biphenotypic type, and 2 cases of biclonal type with granulocytes and lymphocytes); 2 cases were suspected as HAL. On other hand, 5 cases of HAL were assigned to ALL, and 2 cases were misinterpreted as M5a and 1 as M4b. Most of the blast cells of biphenotypic HAL showed lymphoid features, except some cases containing MPO positive granules in blasts, while a few cases exhibited monocytic or nonspecific features. TEM offers advantages in the diagnosis of biclonal type HAL and biphenotypic HAL positive for MPO. However, it is difficult to differentiate MPO-negative cases of biphenotypic HAL from ALL and a few cases may be misinterpreted as M5 by TEM.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Ru YX,Wang HJ,Yang BX,Liu JH,Li ZQ,Li CW,Wang JX,Mi YCdoi
10.1080/019131290968722subject
Has Abstractpub_date
2005-09-01 00:00:00pages
341-7issue
5eissn
0191-3123issn
1521-0758pii
JH0551V0X1585361journal_volume
29pub_type
杂志文章abstract::The coagulation process, including thrombin, fibrin, as well as platelets, plays an important role in hemostasis, contributing to the general well-being of humans. Fibrin formation and platelet activation are delicate processes that are under the control of many small physiological events. Any one of these many proces...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120701376105
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abstract::Abstract Diagnosis of primary ciliary dyskinesia (PCD) by identification of dynein arm loss in transmission electron microscopy (TEM) images can be confounded by high background noise due to random electron-dense material within the ciliary matrix, leading to diagnostic uncertainty even for experienced morphologists. ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,随机对照试验
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abstract::The Dallas consensus was used to reveal active or borderline inflammatory loci by light microscopy (LM). When lymphocyte-cardiocyte interaction was observed by electron microscopy (EM), the deleterious or dormant pattern of inflammatory process was recognized. The first was determined by lymphocytes that adhered to ca...
journal_title:Ultrastructural pathology
pub_type: 临床试验,杂志文章
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abstract::Deciduoid mesothelioma was first described in young females and in the peritoneum, which led to the suggestion that deciduoid mesothelioma was a distinct subtype with specific clinical and pathologic features. Later reports, however, have shown that this type of mesothelioma may also occur in elderly people and in the...
journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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更新日期:1980-04-01 00:00:00
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.861569
更新日期:2014-05-01 00:00:00
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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更新日期:2016-01-01 00:00:00
abstract::Four cases of epithelioid hemangioendothelioma of bone--a borderline malignant tumor of vascular origin--were studied ultrastructurally and immunohistochemically. The epithelioid tumor cells were positive for vimentin, polyclonal and monoclonal cytokeratins, and the endothelial markers factor VIII-related antigen (FVI...
journal_title:Ultrastructural pathology
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