Ultrastructural and immunohistochemical study of epithelioid hemangioendothelioma of bone: coexpression of epithelial and endothelial markers.

Abstract:

:Four cases of epithelioid hemangioendothelioma of bone--a borderline malignant tumor of vascular origin--were studied ultrastructurally and immunohistochemically. The epithelioid tumor cells were positive for vimentin, polyclonal and monoclonal cytokeratins, and the endothelial markers factor VIII-related antigen (FVIII:RAg) and Ulex europaeus agglutinin I. The coexpression of polyclonal cytokeratin and FVIII:RAg was demonstrated by means of step sections in the same tumor cells. The endothelial origin of epithelioid tumor cells was supported ultrastructurally by identification of Weibel-Palade bodies.

journal_name

Ultrastruct Pathol

authors

van Haelst UJ,Pruszczynski M,ten Cate LN,Mravunac M

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

141-9

issue

2

eissn

0191-3123

issn

1521-0758

journal_volume

14

pub_type

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