Abstract:
:Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare aggressive lymphoma derived from plasmacytoid dendritic cells or precursor dendritic cells. Despite some 240 reported cases, its morphology and especially ultrastructure has not been satisfactorily studied. A case is reported of a 13 year old boy, who, despite chemotherapy, died within a 12-month period. The electron microscopy findings - microvillous processes, nuclei with slight irregularities, a moderate amount of heterochromatin, and rough endoplasmic reticulum in the form of long, narrow profiles, often in parallel arrangements - taken together, serve to distinguish BPDCN from other neoplastic cells, such as monocytes, plasma cells and the cells of chronic lymphocyte leukemia.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Ru Y,Zhang P,Dong S,Wang H,Zhao S,Mi Y,Eyden Bdoi
10.3109/01913123.2013.813998subject
Has Abstractpub_date
2014-02-01 00:00:00pages
66-8issue
1eissn
0191-3123issn
1521-0758journal_volume
38pub_type
杂志文章abstract::A metastasizing carcinoid of the gastric stump found 25 years after Billroth II gastric resection for duodenal ulcer is described. Electron microscopy and optical endocrine cell staining proved the tumor to be composed of enterochromaffinlike (ECL) cells. This unusual combination further shows that, at variance with m...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109021888
更新日期:1991-05-01 00:00:00
abstract:OBJECT:To study the relationship between monocyte/histiocyte activation and myelodysplastic syndrome (MDS). METHODS:Analyzing ultrastructure and myeloperoxidase reaction of nucleated cells in bone marrow from 59 cases of MDS by transmission electron microscopy. Four groups of MDS were subdivided on the basis of their ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.888116
更新日期:2014-08-01 00:00:00
abstract::A glomangioma (glomus tumor) arising in the pituitary region is described. The histologic and ultrastructural features were characteristic. The tumor was composed of epithelioid cells arranged in an organoid fashion around vascular channels and contained scattered mast cells. Electron microscopy revealed tumor cells t...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409141853
更新日期:1984-01-01 00:00:00
abstract::By means of optical and electron microscopy and by atomic absorption spectrophotometry in a graphite chamber, this study evaluated the effect of temperature (22-35 degrees C) on lesions in the kidney, liver, and brain, and on concentrations of lead caused by the administration of 2 and 5 mg/kg/IP of lead acetate to Sw...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129609016324
更新日期:1996-05-01 00:00:00
abstract::Myoepithelial cells of salivary gland are uniquely specialized cells; their function is unclear, but the considerable complement of muscle-specific actin suggests contractility is one function. By routine transmission electron microscopy myofilament visualization is variable. Some myoepithelial cells appear to have li...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129209061547
更新日期:1992-09-01 00:00:00
abstract::Clear-cell carcinomas of the female genital tract are uncommon tumors that usually arise in the ovary, cervix, or vagina. The objectives of the present study were to examine the immunohistochemical and ultrastructural characteristics of 18 of these tumors and to determine whether any distinctive features were present ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129609016357
更新日期:1996-11-01 00:00:00
abstract::Abstract Metastases to the pituitary occur more frequently in patients with widespread cancer and mainly involve the posterior lobe. A few cases of metastatic carcinoma to a pituitary adenoma have been described so far. Here, the authors present an additional case of a clear cell renal cell carcinoma (CCRCC) metastati...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913123.2014.937843
更新日期:2014-12-01 00:00:00
abstract::Tissue biopsies and peripheral blood samples from 10 patients with the characteristic clinical features of acquired immunodeficiency syndrome (AIDS) were examined by electron microscopy and ultracytochemical myeloperoxidase technique. Abundant tubuloreticular inclusions (TRI) were detected within the endoplasmic retic...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128309140585
更新日期:1983-06-01 00:00:00
abstract::A technique for immunoelectron microscopy is described whereby tissue is embedded in large (6 x 12 mm) plastic blocks and reembedded ("popped off") directly from semithin (3-microns) sections for thin sectioning. This technique is particularly useful in locating relatively sparse cells or tissue structures. Three acry...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129209074550
更新日期:1992-01-01 00:00:00
abstract::Mitochondrial abnormalities have received relatively little attention in the ultrastructural evaluation of paragangliomas. Review of the few literature references dealing with this issue, however, reveals that quantitative and qualitative changes of these organelles occur in that context. A bladder paraganglioma is de...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409021899
更新日期:1994-11-01 00:00:00
abstract::Thirteen malignant mesotheliomas of a sarcomatous type were studied by light microscopy and ten were studied by electron microscopy. The histologic patterns varied from tumor to tumor, often resembling other soft tissue sarcomas. Electron microscopic observation showed most of the tumors to be composed of primitive ce...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128309140587
更新日期:1983-06-01 00:00:00
abstract::The present study provides ultrastructural information about the acaricidal effects of neem (Azadirachta indica A. Juss) on the ovaries of R. sanguineus engorged females. In general, the main damage caused in the oocytes was alteration in the shape of the cell and of the germinal vesicle, ring-shaped nucleolus, cytopl...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2011.588819
更新日期:2012-02-01 00:00:00
abstract::Electron microscopy is an essential component of myopathology, both in diagnostics and research of neuromuscular diseases. Although recently reduced in the diagnostic armamentarium, it has greatly been expanded to mouse models in research. Mostly it is descriptive, but a few additional techniques in combination with t...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913123.2013.810690
更新日期:2013-10-01 00:00:00
abstract::The c-erbB-2 gene product was demonstrated immunoelectron microscopically in human transitional cell carcinomas of the urinary tract. Two antibodies specific for the c-erbB-2 gene product were used: a polyclonal antibody directed to the intracellular domain and a monoclonal antibody recognizing an epitope in the extra...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129009007219
更新日期:1990-09-01 00:00:00
abstract::An unusual case of metastatic sarcomatoid renal cell carcinoma is presented. Fifteen months after nephrectomy for a typical clear cell carcinoma, a 63-year-old man presented with bilateral pleural effusions, cardiomegaly, and tamponade. A pericardial biopsy showed an anaplastic spindle cell tumor that was strongly ker...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109016245
更新日期:1991-07-01 00:00:00
abstract::In the last two decades, the ability of mesangial cells to respond to various stimuli or injurious agents by altering their phenotype and function has become recognized. The plasticity of these mesangial cells has been linked to the morphological and functional alterations responsible for the pathologic findings. Many...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/01913120600932594
更新日期:2006-11-01 00:00:00
abstract::Disseminated dermal tumors in a 71-year-old male represented the first clinical manifestation of a chronic myelomonocytic leukemia. The dermal infiltrate in one of the nodules consisted predominantly of closely packed pleomorphic Langerhans' cells (LC) with typical Birbeck granules and a strong reactivity for S-100 pr...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128809058219
更新日期:1988-03-01 00:00:00
abstract::Confocal microscope was used to analyze human enamel from 10 deciduous and 10 permanent teeth. Optically sectioned images were obtained. A more intense autofluorescence was found in primary teeth. This finding might be due to the greater presence of organic substances in deciduous enamel. The mean prism diameter measu...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.960544
更新日期:2015-04-01 00:00:00
abstract::This work demonstrates differences between B lymphocytes and T lymphocytes as seen in the scanning electron microscope (SEM). Slides of routinely prepared benign and malignant lymphoid tissues were viewed in the SEM. The location of prominent populations of T lymphocytes and B lymphocytes was verified by immunocytoche...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120050176653
更新日期:2000-07-01 00:00:00
abstract::Elastofibromas have been described as ill-defined tumors, composed of fibroblastic stromal cells and a dense collagenous stroma. A total of 5 elastofibromas from 4 Japanese patients were examined by ultrastructural and immunohistochemical methods. The proliferating fibroblastic stromal cells in the lesion showed Cx43-...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120701350365
更新日期:2007-05-01 00:00:00
abstract::Excess lipofuscin deposition in tissues is a phenomenon observed in normal aging. The amount of lipofuscin in myocardium, liver, skeletal muscle, and adnexal skin structures varies considerably with age and increases in older individuals. In addition, lipofuscin deposition occurs in association with specific, non-age-...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129009076140
更新日期:1990-11-01 00:00:00
abstract::Thickening of capillary walls is a feature of many glomerular diseases. Widening of the wall may be produced by deposits and other changes affecting either subepithelial and subendothelial regions or the glomerular basement membrane itself. Careful light microscopic examination using special stains can distinguish som...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128309140784
更新日期:1983-03-01 00:00:00
abstract::Sclerosing stromal tumors are rare, benign ovarian neoplasms of unknown etiology and histogenesis. Three sclerosing stromal tumors were evaluated by immunohistochemistry and electron microscopy and were compared to two thecomas and nonneoplastic ovarian mesenchymal tissue. The sclerosing stromal tumors and thecomas we...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129209061364
更新日期:1992-05-01 00:00:00
abstract::Monomorphous pituitary adenomas expressing several hormones by immunocytochemistry are common, whereas adenomas displaying multiple immunoreactivities and consisting of more than one morphologic cell types are rare. Three such unusual pituitary adenomas, surgically removed from two patients with acromegaly and one pat...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131299281635
更新日期:1999-05-01 00:00:00
abstract::The clinicopathologic, immunocytochemical, and electron microscopic features of a case of meningeal melanocytoma arising in the phylum terminale are reported. Meningeal melanocytoma is an uncommon tumor that must be distinguished from metastatic or primary malignant melanoma, meningeal melanocytic nevi, pigmented meni...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913129809103356
更新日期:1998-07-01 00:00:00
abstract::A case of lymphoid hyperplasia with prominent plasmacytic proliferation histologically and with polyclonal hypergammaglobulinemia and anemia clinically was reported. This condition in a 54-year-old Japanese male was probably a type of plasma cell dyscrasia similar to a plasma cell variant of Castleman's disease. About...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409018570
更新日期:1984-01-01 00:00:00
abstract::In differentiating diffuse epithelial mesothelioma from metastatic adenocarcinoma in pleural and peritoneal biopsies, the number and form of microvilli and the amount and distribution of tonofilaments are thought to be the most useful criteria. This report details 5 cases of diffuse epithelial mesothelioma in which th...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409141472
更新日期:1984-01-01 00:00:00
abstract::The objective of this study was to investigate the ultrastructural characteristics of hybrid acute leukemia (HAL). Fifteen cases of HAL were studied by transmission electron microscopy (TEM), focusing on organelles and myeloperoxidase (MPO) reaction of leukemic cells. By TEM, 5 out 15 cases of HAL were consistent with...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131290968722
更新日期:2005-09-01 00:00:00
abstract::Deciduoid mesothelioma was first described in young females and in the peritoneum, which led to the suggestion that deciduoid mesothelioma was a distinct subtype with specific clinical and pathologic features. Later reports, however, have shown that this type of mesothelioma may also occur in elderly people and in the...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/0913120290104647
更新日期:2002-11-01 00:00:00
abstract::A new rapid method for the processing of biopsy specimens for electron microscopy is described. The method uses standard reagents and media and employs ultrasonic cleaning bath agitation to accelerate fluid exchange. The procedure takes approximately 2.5 h from specimen excision to polymerized block and gives excellen...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109021307
更新日期:1991-01-01 00:00:00