Abstract:
:Myoepithelial cells of salivary gland are uniquely specialized cells; their function is unclear, but the considerable complement of muscle-specific actin suggests contractility is one function. By routine transmission electron microscopy myofilament visualization is variable. Some myoepithelial cells appear to have limited and only focal aggregates of myofilaments, while others seem to have readily appreciated myofilaments within a longitudinally oriented cytoplasmic zone at the basal portion of the cell. However, immunogold electron microscopy using the anti-muscle-specific actin antibody, HHF35, while indicating a basal distribution for the muscle-isoform of actin in a platelike fashion in certain myoepithelial cells, also reveals that others associated with both intercalated ducts and acini have a more generalized distribution of myofilaments throughout the cytoplasm. Actin was also noted within tonofilaments and double immunogold labeling using both the HHF35 and AE1/AE3 (anticytokeratins) antibodies confirmed the variable interrelationship of these two filaments. Within any one myoepithelial cell, actin and cytokeratins might colocalize in some areas of the cytoplasm containing filaments, but not in adjacent zones. These results suggest that intermediate filaments and myofilaments are complexly organized in myoepithelial cells, and that quantitative and qualitative differences exist in the expression and distribution of intermediate filaments and myofilaments. These cells are likely structurally, if not functionally, heterogeneous.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Norberg L,Dardick I,Leung R,Burford-Mason AP,Rippstein Pdoi
10.3109/01913129209061547subject
Has Abstractpub_date
1992-09-01 00:00:00pages
555-68issue
5eissn
0191-3123issn
1521-0758journal_volume
16pub_type
杂志文章abstract::Low molecular weight proteins are normally, essentially, entirely catabolized by the proximal tubules. Physiological and pathological aspects of the renal interactions of three of these proteins: light chains, B-2 microglobulin, and myoglobin share similarities, but are also unique in certain ways. In pathological con...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913129409016277
更新日期:1994-01-01 00:00:00
abstract::We have carried out a systematic ultrastructural study of the bacilli, the cell-mediated response in the host, and the dermal microvasculature in lepromatous (LL), borderline lepromatous (BL), and borderline tuberculoid (BT) types of active leprosy (eight cases). In the types of least resistance (LL and BL), macrophag...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409023213
更新日期:1994-07-01 00:00:00
abstract::Inflammation in the liver is an extraintestinal manifestation that is frequently seen during inflammatory bowel diseases (IBD). The authors investigated histopathologycal, ultrastructural and antioxidant effects of dexmedetomidine (Dex) on liver during trinitrobenzene sulfonic acid (TNBS)-induced inflammatory bowel di...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.829150
更新日期:2015-02-01 00:00:00
abstract::A group of 33 functionless pituitary tumors with small argyrophil groups (SAG) were collected from a series of 200 pituitary adenomas (16.5% of all adenomas). Histologically, the tumors showed an unusually high frequency of trabecular patterns, perivascular pseudo-rosettes, and oncocytoid transformation. Immunoreactiv...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128309140570
更新日期:1983-01-01 00:00:00
abstract::Mitochondrial abnormalities have received relatively little attention in the ultrastructural evaluation of paragangliomas. Review of the few literature references dealing with this issue, however, reveals that quantitative and qualitative changes of these organelles occur in that context. A bladder paraganglioma is de...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409021899
更新日期:1994-11-01 00:00:00
abstract::Since 1980 when Sibley and coworkers first described a nodal neoplasm of unknown histogenesis with striking surface microvilli for which they introduced the term "anemone cell," a series of reports have appeared in the literature illustrating tumors with similar ultrastructural features. While most reported cases show...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120309931
更新日期:2003-03-01 00:00:00
abstract::For wide application of low-energy laser irradiation in the pulmonary clinic, study of the structural basis of the therapeutic effect is necessary. The aim of this research is to describe the structural changes of the blood and lymphatic capillaries in the respiratory tissues during inflammation and following laser bi...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120050132921
更新日期:2000-05-01 00:00:00
abstract::Conidiobolus coronatus is a major insect pathogen belonging to the fungal order Entomophthorales, causing a rare subcutaneous infection of the nasofacial region, resulting in swelling of predominantly the nose, mouth, and perinasal tissue. Later in the course of the infection firm, painless, subcutaneous nodules devel...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120500482013
更新日期:2006-01-01 00:00:00
abstract::This study aimed to examine the surface characteristics of erosive enamel in extracted human teeth by scanning electron microscopy. Morphologic changes in naturally eroded enamel depend on the stages of dental erosion. In its early stages, the enamel surfaces show a honeycomb appearance due to the dissolution of ename...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2015.1054014
更新日期:2015-01-01 00:00:00
abstract::This work demonstrates differences between B lymphocytes and T lymphocytes as seen in the scanning electron microscope (SEM). Slides of routinely prepared benign and malignant lymphoid tissues were viewed in the SEM. The location of prominent populations of T lymphocytes and B lymphocytes was verified by immunocytoche...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120050176653
更新日期:2000-07-01 00:00:00
abstract::Intranuclear helioid bodies were identified by light microscopy in eight cases of mammary intraductal hyperplasia, only one of which was atypical. These structures appear as round, intranuclear eosinophilic bodies on light microscopic examination. When prominent, they may be and have been mistaken for viral inclusions...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109021889
更新日期:1991-05-01 00:00:00
abstract::The c-erbB-2 gene product was demonstrated immunoelectron microscopically in human transitional cell carcinomas of the urinary tract. Two antibodies specific for the c-erbB-2 gene product were used: a polyclonal antibody directed to the intracellular domain and a monoclonal antibody recognizing an epitope in the extra...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129009007219
更新日期:1990-09-01 00:00:00
abstract::In vitro studies have provided much information regarding the process of glomerular AL-amyloidogenesis. Research efforts have been successful in deciphering how glomerulopathic light chains interact with mesangial cells. The sequential steps involved in the genesis of amyloid fibrils include interactions with surface ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.861568
更新日期:2014-04-01 00:00:00
abstract::Electron microscopic investigation of biopsy materials from Kaposi sarcoma (KS) skin lesions of 2 African AIDS patients occasionally revealed fungal cells within the tumor tissue. The spherical cells were surrounded by a triple-layered cell wall and were not encapsulated. The ultrastructural characteristics of the cel...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120500520960
更新日期:2006-05-01 00:00:00
abstract::Disseminated dermal tumors in a 71-year-old male represented the first clinical manifestation of a chronic myelomonocytic leukemia. The dermal infiltrate in one of the nodules consisted predominantly of closely packed pleomorphic Langerhans' cells (LC) with typical Birbeck granules and a strong reactivity for S-100 pr...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128809058219
更新日期:1988-03-01 00:00:00
abstract::The study aims to investigate the protective effect of Pimpinella anisum oil on aspartame (ASP) which resulted in cerebellar changes. The rats were divided into four equal groups: Group 1: (control group): served as control animals. Group 2: control P. anisum oil received .5 mL/kg/d/b wt. once daily. Group 3 (ASP grou...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.889259
更新日期:2014-05-01 00:00:00
abstract::Microvascular injury is an important factor in renal allograft survival. Repeated episodes of endothelial injury from chronic antibody-mediated rejection typically manifest at the ultrastructural level as circumferential multilayering of remodeled glomerular basement membrane material and peritubular capillary basal l...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2018.1484542
更新日期:2018-07-01 00:00:00
abstract::The electron microscope has been used with great skill in many aspects of the acquired immunodeficiency syndrome. It has played a critical role in classifying the human immunodeficiency virus, in characterizing the morphogenesis and gene products of the virus, and in elucidating the host cell targets and interactions....
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913129209074561
更新日期:1992-01-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) is one of the most commonly malignant tumors worldwide, characterized by the presence of many heterogeneous molecular cell events that contribute to tumor growth and progression. Endocytic processes are intimately involved in various pathological conditions, including cancer, since they ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2019.1701167
更新日期:2019-01-01 00:00:00
abstract::It is generally accepted that a glomerular basement membrane (GBM) thinner than 200 nm should be considered below normal. When this abnormality has a global and diffuse distribution, the associated clinical condition is a benign familial hematuria related to mutations of the COL4A4/COL4A3 genes, or an Alport syndrome....
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120490445016
更新日期:2004-03-01 00:00:00
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2019.1671927
更新日期:2019-01-01 00:00:00
abstract::Hemangiomas, the most common tumors of infancy, are characterized by a postnatal period of rapid growth, followed by a phase of gradual involution. The proliferative phase is characterized by increased numbers of endothelial and mast cells and thickened basement membrane. Ultrastructural analysis of hemangiomas in the...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128609014593
更新日期:1986-01-01 00:00:00
abstract:UNLABELLED:The cell adhesion molecules (CAMs) CD44 standard (CD44s) and its variant 6 (CD44v6) are involved in the progression and invasion of human malignancies. However, discrepancies in the prognostic value of CD44s and CD44v6 expression need to be addressed. AIMS:To investigate the expression of CD44s and CD44v6 i...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2011.651522
更新日期:2012-05-01 00:00:00
abstract::Sibutramine is used in the treatment of obesity due to its ability to influence feelings of hunger and satiety by inhibiting the re-uptake of serotonin and noradrenalin in the central nervous system (CNS). Sibutramine use has been associated with numerous adverse events in particular cardiovascular complications possi...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.946635
更新日期:2014-12-01 00:00:00
abstract::Helicobacter pylori is believed to cause chronic active gastritis. Infection/colonization of the gastric mucosal surface induces a mucosal inflammatory reaction in the form of lymphocytic aggregates, plasma cells and, particularly, neutrophils, which may, in turn, damage the mucosal epithelium. In vitro studies demons...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131200750035049
更新日期:2000-09-01 00:00:00
abstract::Motor end plates of the intrinsic laryngeal muscles in amyotrophic lateral sclerosis (ALS) were examined light and electron microscopically. Light microscopically, typical neurogenic changes such as small angulated fibers and grouped atrophy were found in the intrinsic laryngeal muscles. Acetylcholinesterase (AchE) ac...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129809032266
更新日期:1998-03-01 00:00:00
abstract::Hydrosalpinx is a disease commonly observed in women and characterized by the obstruction which is in the shape of a fluid-filled sac at the distal part of tuba uterina closed to the ovary. In this study, we aimed to obtain endometrial tissue samples from the hydrosalpinx patients, before and after the surgical treatm...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2019.1600087
更新日期:2019-01-01 00:00:00
abstract::The ultrastructure of 10 myxoid liposarcomas from 9 patients is presented. Features closely resembling those of developing fetal adipose tissue were seen in all tumors. THe various cell types identified ranged from undifferentiated cells to typical multivacuolated and univacuolated lipoblasts. In addition, a secretory...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128009141413
更新日期:1980-04-01 00:00:00
abstract::Due to their infrequency and multiplicity of histopathology, myoepitheliomas present difficulties in diagnosis and classification. Cellular varieties can be misdiagnosed as malignancies. Improvements in and clarification of diagnostic criteria are, therefore, required. A key to determining diagnostic criteria for myoe...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913129509021906
更新日期:1995-09-01 00:00:00
abstract::We describe in this work the presence of extracellular vesicles (EVs) along different cell types, especially cordocytes, in various clinical conditions of the human brain (atherothrombotic disease, cerebral tumors, hygroma durae matris, intracerebral cysts, Moyamoya disease and parenchymatous hematoma) using transmiss...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.981327
更新日期:2015-05-01 00:00:00