Abstract:
:Excess lipofuscin deposition in tissues is a phenomenon observed in normal aging. The amount of lipofuscin in myocardium, liver, skeletal muscle, and adnexal skin structures varies considerably with age and increases in older individuals. In addition, lipofuscin deposition occurs in association with specific, non-age-related processes; these include melanosis coli, the so-called brown bowel syndrome, and the black thyroid. Localized lipofuscinosis has also been described in the gallbladder, esophagus, and fallopian tubes. The present article adds lipofuscinosis vesicalis to the list of entities characterized by focal lipofuscin deposition. All cases have a characteristic gross appearance that is somewhat variable from entity to entity and in some cases may suggest clinically an ominous pathologic process.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Herrera GA,Turbat-Herrera EA,Lockard VGdoi
10.3109/01913129009076140subject
Has Abstractpub_date
1990-11-01 00:00:00pages
529-35issue
6eissn
0191-3123issn
1521-0758journal_volume
14pub_type
杂志文章abstract::A variety of neoplasms with rhabdoid differentiation have been reported in many sites. The authors describe a case of gastrointestinal stromal tumor (GIST) of the stomach that exhibited prominent rhabdoid features. Immunohistochemically, the tumor cells displayed positive staining for vimentin, c-kit, CD34, and alpha ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120490475707
更新日期:2004-05-01 00:00:00
abstract::Deciduoid mesothelioma was first described in young females and in the peritoneum, which led to the suggestion that deciduoid mesothelioma was a distinct subtype with specific clinical and pathologic features. Later reports, however, have shown that this type of mesothelioma may also occur in elderly people and in the...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/0913120290104647
更新日期:2002-11-01 00:00:00
abstract::The study aims to investigate the protective effect of Pimpinella anisum oil on aspartame (ASP) which resulted in cerebellar changes. The rats were divided into four equal groups: Group 1: (control group): served as control animals. Group 2: control P. anisum oil received .5 mL/kg/d/b wt. once daily. Group 3 (ASP grou...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.889259
更新日期:2014-05-01 00:00:00
abstract::Cutaneous nerves showed multiple ultrastructural abnormalities in a patient with incontinentia pigmenti. Fetal nerve bundles were seen both in the dermis and entering the epidermis. A cell with some Schwann cell features was identified above the basal layer amid keratinocytes. Dermal melanophages were in close apposit...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128809064214
更新日期:1988-01-01 00:00:00
abstract::Primary ciliary dyskinesia (PCD) is a genetic disorder causing chronic oto-sino-pulmonary disease. No single diagnostic test will detect all PCD cases. Transmission electron microscopy (TEM) of respiratory cilia was previously considered the gold standard diagnostic test for PCD, but 30% of all PCD cases have either n...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/01913123.2017.1362088
更新日期:2017-11-01 00:00:00
abstract::The present study provides further insight into the structural processes that remodel pulmonary capillaries in the injured adult lung. Early in hyperoxia acute lung injury (HALI), many sub-dividing segments are present throughout the capillary network before segment occlusion and loss predominate and capillary density...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.888113
更新日期:2014-05-01 00:00:00
abstract::Sclerosing stromal tumors are rare, benign ovarian neoplasms of unknown etiology and histogenesis. Three sclerosing stromal tumors were evaluated by immunohistochemistry and electron microscopy and were compared to two thecomas and nonneoplastic ovarian mesenchymal tissue. The sclerosing stromal tumors and thecomas we...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129209061364
更新日期:1992-05-01 00:00:00
abstract::The aim of this study was to examine the effect of the different protein supports in the cryopreservation solution on improving human ovarian tissue preservation after frozen-thawed procedures. Biopsies of ovarian cortical tissue were obtained from 14 subjects. All specimens were cryopreserved using a slow freezing/ra...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120600820187
更新日期:2006-07-01 00:00:00
abstract::The term "neuronal ceroid lipofuscinosis" (NCL) describes a complex of inherited neurodegenerative conditions associated with storage of lipopigments in brain tissue. In 1989 Dyken proposed a classification of NCL based on the age, clinical symptoms, and ultrastructural aspects of the lipopigments. At the ultrastructu...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131201300004681
更新日期:2001-01-01 00:00:00
abstract::Thirteen malignant mesotheliomas of a sarcomatous type were studied by light microscopy and ten were studied by electron microscopy. The histologic patterns varied from tumor to tumor, often resembling other soft tissue sarcomas. Electron microscopic observation showed most of the tumors to be composed of primitive ce...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128309140587
更新日期:1983-06-01 00:00:00
abstract::Strabismus is an ocular disorder characterized by partial or complete inability to keep eye alignment. It represents a very common ocular problem at ophthalmology clinics worldwide. The current study aimed to show the most encountered ultrastructural changes in extraocular muscles (EOMs) collected from patients with d...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2019.1671927
更新日期:2019-01-01 00:00:00
abstract::A 60-year-old female presented with a history of hoarseness, cough, chest pain, and dyspnea and a needle biopsy sample was submitted for histology. Light microscopy showed sheets of tumor cells with eosinophilic cytoplasm containing multiple crystals and eccentrically located nuclei. Electron microscopy showed large i...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120601172489
更新日期:2007-01-01 00:00:00
abstract::Low-grade fibrosarcomas have recently gained increasing attention in the literature, especially with the fall in popularity polls of the ubiquitous malignant fibrous histiocytoma (MFH). Firstly, most tumors previously known as myxoid MFH are labeled presently as myxofibrosarcomas. Secondly, the recognition and better ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131290882259
更新日期:2004-09-01 00:00:00
abstract::Cellular (c) fibronectins (Fn) differ biochemically, immunologically, and functionally from plasma fibronectins (pFn). Most existing data on Fn distribution in the normal and diseased liver require revision because those studies were based on reagents that did not distinguish pFn from cFn and predated the development ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129509014601
更新日期:1995-01-01 00:00:00
abstract::A 28-year-old man presented with left cervical lymph node metastases and a 7-cm mass in the left lobe of the liver. Biopsy material from both sites revealed a fibrolamellar hepatocarcinoma (FLHC) with immunocytochemical and ultrastructural evidence of neurosecretory differentiation. The patient refused treatment. He d...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409016302
更新日期:1994-01-01 00:00:00
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journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913121003729806
更新日期:2010-08-01 00:00:00
abstract::Giant cell carcinoma of the lung (GCCL) is an uncommon and extremely aggressive variant of lung cancer. Characteristic microscopic findings include marked pleomorphism, aggregates of mononucleated or multinucleated giant cells (or both), a general lack of architectural cohesiveness, extensive necrosis, and endocytosis...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109016231
更新日期:1991-03-01 00:00:00
abstract::Alterations in tannic acid (TA) binding capacity of cell surface carbohydrates in normal, premalignant, and malignant squamous epithelium of the human uterine cervix have been studied using electron microscopic visualization in combination with microdensitometric evaluation. While in normal epithelium there is distinc...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409018586
更新日期:1984-01-01 00:00:00
abstract::Fabry disease is an X-linked recessive lysosomal storage disease caused by a deficiency of α-galactosidase A, with characteristic ultrastructural cytoplasmic myelin-like inclusions. Renal lesions are seen in male and variably in heterozygous female patients. One previous report has described Fabry disease involving a ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2010.538136
更新日期:2011-04-01 00:00:00
abstract::A case of myoepithelial carcinoma arising in a benign myoepithelioma of the minor salivary gland in a 71-year-old patient is reported. The tumor presented initially on the palate and had been diagnosed as "benign lesion" 40 years before. It recurred 22, 36, and 40 years after initial presentation, and a similar histop...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913129609016309
更新日期:1996-03-01 00:00:00
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journal_title:Ultrastructural pathology
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doi:10.3109/01913123.2014.946635
更新日期:2014-12-01 00:00:00
abstract::Cyclosporin A is an immunosuppressant drug used to prevent graft rejection in organ transplantation. Side effects include toxicity to the kidney and liver. Recently, many experimental and clinical data have demonstrated that CsA-induced toxicity is associated with increased production of reactive oxygen species (ROS) ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.810686
更新日期:2013-10-01 00:00:00
abstract::The ultrastructural and immunohistochemical features of a primary tumor of the ileum showing the classic histologic features of an inflammatory fibroid polyp (IFP) of the gastrointestinal tract are presented. Ultrastructurally the proliferating cells showed a combination of fibroblastic and histiocytic features, with ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913129009025123
更新日期:1990-03-01 00:00:00
abstract::The electron microscope has been used with great skill in many aspects of the acquired immunodeficiency syndrome. It has played a critical role in classifying the human immunodeficiency virus, in characterizing the morphogenesis and gene products of the virus, and in elucidating the host cell targets and interactions....
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913129209074561
更新日期:1992-01-01 00:00:00
abstract::A case of a malignant meningioma arising in the left parapharyngeal space in a 29-year-old woman is reported. Electron microscopic examination of the tumor was critical in establishing the diagnosis. Meningiomas of the parapharyngeal space are extremely rare. This constitutes the first malignant case documented in thi...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129609023238
更新日期:1996-01-01 00:00:00
abstract::Finger pulp biopsies of 31 patients suffering from Raynaud's syndrome (RS) were investigated by light and electron microscopy. The patients suffered from various underlying diseases. Interest was focused on the vascular changes and nerve and connective tissue alterations, especially the elastic fiber changes. In the d...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128209016642
更新日期:1982-04-01 00:00:00
abstract::Advances in biochemistry, physiology, immunology, and cytochemistry, combined with a variety of new approaches for the evaluation of fine structure, have yielded new insights into the structural physiology and pathology of blood platelets. Subpopulations of platelet granules have been clearly defined; they include the...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913128009140561
更新日期:1980-10-01 00:00:00
abstract::We describe in this work the presence of extracellular vesicles (EVs) along different cell types, especially cordocytes, in various clinical conditions of the human brain (atherothrombotic disease, cerebral tumors, hygroma durae matris, intracerebral cysts, Moyamoya disease and parenchymatous hematoma) using transmiss...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.981327
更新日期:2015-05-01 00:00:00
abstract::Aberrant transcription of the FHIT gene has been observed in many solid tumors, suggesting that 5'-CpG island methylation of the FHIT gene is involved in tumor development. The authors investigated the status of the 5'-CpG island methylation of the FHIT gene and protein expression in a series of 40 cervical carcinomas...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120390250329
更新日期:2003-11-01 00:00:00
abstract::We have carried out a systematic ultrastructural study of the bacilli, the cell-mediated response in the host, and the dermal microvasculature in lepromatous (LL), borderline lepromatous (BL), and borderline tuberculoid (BT) types of active leprosy (eight cases). In the types of least resistance (LL and BL), macrophag...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409023213
更新日期:1994-07-01 00:00:00