Ribosome-lamella complex of the lymphocytes in a case of plasmacytic lymphadenopathy with polyclonal hypergammaglobulinemia.

Abstract:

:A case of lymphoid hyperplasia with prominent plasmacytic proliferation histologically and with polyclonal hypergammaglobulinemia and anemia clinically was reported. This condition in a 54-year-old Japanese male was probably a type of plasma cell dyscrasia similar to a plasma cell variant of Castleman's disease. About 19% of apparently nonatypical lymphocytes in the biopsy material of this case were found to have ribosome-lamella complexes (RLC) similar to those previously described in patients with hairy cell leukemia and some other hematologic disorders. An intimate association with the rough endoplasmic reticulum of these structures suggested aberrant protein synthesis by B-lymphocytes.

journal_name

Ultrastruct Pathol

authors

Mikata A,Suzuki S,Suzuki H,Higo O,Shimoyama M

doi

10.3109/01913128409018570

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

161-6

issue

2-3

eissn

0191-3123

issn

1521-0758

journal_volume

6

pub_type

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