Electron microscopy reveals fungal cells within tumor tissue from two African patients with AIDS-associated Kaposi sarcoma.

Abstract:

:Electron microscopic investigation of biopsy materials from Kaposi sarcoma (KS) skin lesions of 2 African AIDS patients occasionally revealed fungal cells within the tumor tissue. The spherical cells were surrounded by a triple-layered cell wall and were not encapsulated. The ultrastructural characteristics of the cells resemble those of Candida albicans organisms. Neither patient showed clinical signs of a generalized fungal infection. The presence of Candida albicans in the KS tissue specimens seems to represent an early and asymptomatic stage of cutaneous candidiasis in the 2 severely immunocompromised AIDS patients.

journal_name

Ultrastruct Pathol

authors

Marquart KH

doi

10.1080/01913120500520960

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

187-92

issue

3

eissn

0191-3123

issn

1521-0758

pii

H88702081214H324

journal_volume

30

pub_type

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