Abstract:
:Recently, interest has been increasing for human decellularized matrices, due to their ability to reduce numerous side effects related to hernia repair. To date, only animal studies investigated the biological interaction post-implant of human decellularized matrices for soft tissue repair. Therefore, the aim of this study was to evaluate the morphological response one year post implant of human decellularized matrix, through morphological analysis of human biopsies. The histological and ultrastructural results revealed a perfect cellular repopulation and neoangiogenesis, with minimal inflammatory response and a well-organized collagen matrix. The results have indicated that this scaffold can be an effective treatment for hernia.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Ghetti M,Papa V,Deluca G,Purpura V,Ruscelli P,Melandri D,Capirossi D,Nigrisoli E,Minghetti P,Bondioli E,Cenacchi Gdoi
10.1080/01913123.2017.1365788subject
Has Abstractpub_date
2018-01-01 00:00:00pages
32-38issue
1eissn
0191-3123issn
1521-0758journal_volume
42pub_type
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