Microvascular changes in human gastric carcinomas with coagulative necrosis: an ultrastructural study.


:Ultrastructural findings in three cases of gastric carcinoma with coagulative necrosis are reviewed with special emphasis on microvascular changes. Intratumoral microvasculature revealed more or less stabilized vessels. Some were characterized by a close association between pericytes and endothelial cells, whereas others showed laminated basement membrane, with a loose association between pericytes and endothelial cells. Some mural cells exhibited ultrastructural signs of regressive changes, including lipofuscin granules, swollen mitochondria, and cytoplasmic lucency. These findings are discussed in relationship to a number of recent studies of the microvascular injury caused by hypoxia and reoxygenation, in humans and animals.


Ultrastruct Pathol


Caruso RA,Fedele F,Finocchiaro G,Pizzi G,Nunnari M,Gitto G,Fabiano V,Rigoli L




Has Abstract


2008-09-01 00:00:00














  • Low-grade spindle cell carcinoma of the kidney.

    abstract::The authors report a renal cell carcinoma composed largely of spindle cells of Fuhrman's nuclear grade II in which the bland appearance of the cells and low mitotic index were reminiscent of a benign or low-grade smooth muscle tumor. Keratin immunostaining was positive, but evidence of epithelial differentiation was o...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Lloreta J,Corominas JM,Munné A,Domínguez D,Bielsa O,Gelabert A,Serrano S

    更新日期:1998-01-01 00:00:00

  • Gastrointestinal stromal tumor of the stomach with rhabdoid phenotype: immunohistochemical, ultrastructural, and immunoelectron microscopic evaluation.

    abstract::A variety of neoplasms with rhabdoid differentiation have been reported in many sites. The authors describe a case of gastrointestinal stromal tumor (GIST) of the stomach that exhibited prominent rhabdoid features. Immunohistochemically, the tumor cells displayed positive staining for vimentin, c-kit, CD34, and alpha ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Richmond JA,Mount SL,Schwarz JE

    更新日期:2004-05-01 00:00:00

  • An ultrastructural study of mast cell interactions in hemangiomas.

    abstract::Hemangiomas, the most common tumors of infancy, are characterized by a postnatal period of rapid growth, followed by a phase of gradual involution. The proliferative phase is characterized by increased numbers of endothelial and mast cells and thickened basement membrane. Ultrastructural analysis of hemangiomas in the...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Dethlefsen SM,Mulliken JB,Glowacki J

    更新日期:1986-01-01 00:00:00

  • Ultrastructural changes suggestive of focal segmental glomerulosclerosis in atypical minimal change nephrotic syndrome.

    abstract::In an attempt to recognize early stages of focal segmental glomerulosclerosis (FSGS) in patients with a clinical course suggesting a diagnosis other than minimal change disease (MCD) and normal histology, or minor, nondiagnostic changes on light microscopy (LM), we used a protocol for systematic and extensive electron...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Ben-Bassat M,Braslavsky D,Lotan D,Eisenstein B,Davidovitz M,Stark H

    更新日期:1988-01-01 00:00:00

  • Epididymal ultrastructural changes associated with chronic cholestasis after bile duct ligation in adult rats.

    abstract::Testicular atrophy and testesterone insufficiency have been commonly reported associated with chronic liver diseases. Though testosterone dependent, the epididymal changes induced by liver disease have never been studied before. Thus, this study aimed to assess the ultrastructural events in the epididymis of rats with...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Mahmoud YI,Abo-Zeid FS

    更新日期:2018-07-01 00:00:00

  • A fast method for processing biologic material for electron microscopic diagnosis in infectious disease.

    abstract::A fast method for processing biologic material for electron microscopy for precise and specific diagnosis of infectious agents is an increasing necessity. After different, reportedly fast methods were tested, a useful and quick technique was developed that provides well-preserved cellular structures, enabling the etio...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Duarte MI,Mariano ON,Takakura CF,Everson D,Corbett CE

    更新日期:1992-07-01 00:00:00

  • Angiomyolipoma of the kidney with lymph node involvement.

    abstract::A case of renal angiomyolipoma with regional lymph node involvement is added to 20 cases previously reported. This represents the 11th case reported in a non-tuberous sclerosis patient. The electron microscopic features of the tumor are discussed and correlated with the light microscopic findings. ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Ansari SJ,Stephenson RA,Mackay B

    更新日期:1991-07-01 00:00:00

  • Ultrastructural analysis of the oocytes of female Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) ticks subjected to the action of Azadirachta indica A. Juss (neem).

    abstract::The present study provides ultrastructural information about the acaricidal effects of neem (Azadirachta indica A. Juss) on the ovaries of R. sanguineus engorged females. In general, the main damage caused in the oocytes was alteration in the shape of the cell and of the germinal vesicle, ring-shaped nucleolus, cytopl...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Denardi SE,Bechara GH,de Oliveira PR,Mathias MI

    更新日期:2012-02-01 00:00:00

  • Betulinic acid induces apoptosis and ultrastructural changes in MDA-MB-231 breast cancer cells.

    abstract::The aim of this study is to investigate the effects of betulinic acid (BA) on triple-negative breast cancer MDA-MB-231 cells and observe the ultrastructural changes. The concentration of BA required to induce apoptosis in MDA-MB-231 cells has been previously reported. In this study, a cell counting kit-8 proliferation...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Gao Y,Ma Q,Ma YB,Ding L,Xu XL,Wei DF,Wei L,Zhang JW

    更新日期:2018-01-01 00:00:00

  • Clear cell leiomyoma (leiomyoblastoma) of the uterus: ultrastructural observations.

    abstract::The ultrastructure of a benign uterine epithelioid leiomyoma with prominent clear cells ("leiomyoblastoma") was studied to define the subcellular changes that yield the distinctive light microscopic pattern of this rare lesion. The main constituent of the cytoplasm was multiple cytolysosomes composed of vesicular, mem...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Mazur MT,Priest JB

    更新日期:1986-01-01 00:00:00

  • Evolutionary origin of eukaryotic cells.

    abstract::This article reviews literature on the transition from rudimentary prokaryotic life to eukaryotes. An overview of the differences between these organisms and theories of eukaryogenesis are reviewed. Various methods of investigating the transformation from prokaryotes to eukaryotes are elaborated, including the fossil,...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审


    authors: Kostianovsky M

    更新日期:2000-03-01 00:00:00

  • Differences in nuclear pore density among human choroidal melanoma cell types.

    abstract::Two cases of mixed cell type choroidal melanoma were examined by means of conventional and freeze-fracture electron microscopy. Data on average nuclear pore density were readily collected from freeze-fracture replicas of spindle A, spindle B, and epithelioid cells. Highly significant (p less than 0.001) differences in...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Sacks-Wilner R,Freddo TF

    更新日期:1990-07-01 00:00:00

  • Myocardiocyte ultrastructure and morphometrical analysis in hamsters experimentally infected with Trypanosoma cruzi.

    abstract::The aim of this work was the study of ultrastructural morphologic and morphometric changes in myocardiocytes from chronic chagasic hamsters (Mesocricetus auratus), comparatively with changes described in other animal models and in human Chagas disease. Four chagasic animals and three nonchagasic controls were studied....

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Colmanetti FH,Teixeira Vde P,Rodrigues ML,Chica JE,Reis Md,dos Santos VM

    更新日期:2005-03-01 00:00:00

  • 5'-CpG island methylation of the FHIT gene is associated with reduced protein expression and higher clinical stage in cervical carcinomas.

    abstract::Aberrant transcription of the FHIT gene has been observed in many solid tumors, suggesting that 5'-CpG island methylation of the FHIT gene is involved in tumor development. The authors investigated the status of the 5'-CpG island methylation of the FHIT gene and protein expression in a series of 40 cervical carcinomas...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Wu Q,Shi H,Suo Z,Nesland JM

    更新日期:2003-11-01 00:00:00

  • Immunogold localization of actin and cytokeratin filaments in myoepithelium of human parotid salivary gland.

    abstract::Myoepithelial cells of salivary gland are uniquely specialized cells; their function is unclear, but the considerable complement of muscle-specific actin suggests contractility is one function. By routine transmission electron microscopy myofilament visualization is variable. Some myoepithelial cells appear to have li...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Norberg L,Dardick I,Leung R,Burford-Mason AP,Rippstein P

    更新日期:1992-09-01 00:00:00

  • Protective effect of tetrahydrobiopterin on hepatic and renal damage after acute cadmium exposure in male rats.

    abstract::Cadmium (Cd) has been recognized as one of the most important environmental and industrial pollutants. This study investigated the impact of acute exposure to Cd on oxidative stress and the inflammatory marker interleukin-6 (IL-6) in the plasma of rats and the histological picture of liver and kidney, as well as to ex...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Mostafa DG,Ahmed SF,Hussein OA

    更新日期:2018-11-01 00:00:00

  • Focal ellipsoid deposits in the atrial myocytes of Syrian hamster.

    abstract::A peculiar hyaline sarcoplasmic inclusion in the atrial myocytes of old female Syrian hamsters is described. This type of inclusion resembles that described in rare human cardiomyopathy. They have also been described in other rodents and have been speculated eventually to contain atrial natriuretic factor (ANF). The p...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Gilloteaux J,Jennes L,Stoeckel ME,Vanderhaeghen JJ

    更新日期:1994-01-01 00:00:00

  • Thickening of glomerular capillary walls: a guide to differential diagnosis by electron microscopy.

    abstract::Thickening of capillary walls is a feature of many glomerular diseases. Widening of the wall may be produced by deposits and other changes affecting either subepithelial and subendothelial regions or the glomerular basement membrane itself. Careful light microscopic examination using special stains can distinguish som...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Seymour AE,Canny A,Spargo BH

    更新日期:1983-03-01 00:00:00

  • Low magnification transmission electron microscopy in diagnostic pathology.

    abstract::Transmission electron microscopy examination of selected diagnostic specimens, that is, renal and nerve biopsies, can be greatly facilitated by the implementation of slot grid preparations that are inherently devoid of any grid bars. Such preparations are conducive to screening and photography at both low and intermed...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Rippstein P,Cavell S,Boivin M,Dardick I

    更新日期:1987-01-01 00:00:00

  • Weber-Christian disease associated with the tip variant of focal segmental glomerulosclerosis: a case report.

    abstract::Weber-Christian disease (W-CD) is associated with relapsing nodular panniculitis and a variety of systemic findings. Renal parenchymal involvement has been rarely reported. The authors describe a case of nephrotic syndrome in an African-American man with a W-CD flare. The patient had chills and low-grade fever with pa...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Sterling KA,Karam S,Taylor N,Cathro HP

    更新日期:2012-12-01 00:00:00

  • Immunohistochemical features of giant cell carcinoma of the lung: patterns of expression of cytokeratins, vimentin, and the mucinous glycoprotein recognized by monoclonal antibody A-80.

    abstract::Giant cell carcinoma of the lung (GCCL) is an uncommon and extremely aggressive variant of lung cancer. Characteristic microscopic findings include marked pleomorphism, aggregates of mononucleated or multinucleated giant cells (or both), a general lack of architectural cohesiveness, extensive necrosis, and endocytosis...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Chejfec G,Candel A,Jansson DS,Warren WH,Koukoulis GK,Gould JE,Manderino GL,Gooch GT,Gould VE

    更新日期:1991-03-01 00:00:00

  • Lithium effects on vesicular trafficking in hepatocellular carcinoma cells.

    abstract::Hepatocellular carcinoma (HCC) is one of the most commonly malignant tumors worldwide, characterized by the presence of many heterogeneous molecular cell events that contribute to tumor growth and progression. Endocytic processes are intimately involved in various pathological conditions, including cancer, since they ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Taskaeva I,Bgatova N,Gogaeva I

    更新日期:2019-01-01 00:00:00

  • Ultrastructure of Developing Feline Nonciliated Bronchiolar Epithelial Cells.

    abstract::The ultrastructure of the developing bronchiolar cell was studied in six age groups: prenatal (60 d post-conception); postnatal (1-, 7-, 14- and 21-day-old); and adult. Following intratracheal fixation, the lung tissue was processed for scanning and transmission electron microscopy. The lining of terminal bronchioles ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Al-Tikriti MS,Henry RW

    更新日期:2015-01-01 00:00:00

  • Neuronal ceroid lipofuscinosis: an ultrastructural, genetic, and clinical study report.

    abstract::The term "neuronal ceroid lipofuscinosis" (NCL) describes a complex of inherited neurodegenerative conditions associated with storage of lipopigments in brain tissue. In 1989 Dyken proposed a classification of NCL based on the age, clinical symptoms, and ultrastructural aspects of the lipopigments. At the ultrastructu...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Boldrini R,Biselli R,Santorelli FM,Bosman C

    更新日期:2001-01-01 00:00:00

  • Spectrum of low-grade fibrosarcomas: a comparative ultrastructural analysis of low-grade myxofibrosarcoma and fibromyxoid sarcoma.

    abstract::Low-grade fibrosarcomas have recently gained increasing attention in the literature, especially with the fall in popularity polls of the ubiquitous malignant fibrous histiocytoma (MFH). Firstly, most tumors previously known as myxoid MFH are labeled presently as myxofibrosarcomas. Secondly, the recognition and better ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Antonescu CR,Baren A

    更新日期:2004-09-01 00:00:00

  • Light and electron microscopic changes in the kidney of Wistar rats following treatment with cyclosporine A.

    abstract::The morphological changes found in kidneys of patients undergoing chronic Cyclosporine A (CSA) treatment could, despite of numerous attempts, not yet be reproduced in reliable experimental models. The purpose of the present investigation was to systematically scan the in vivo fixed kidneys in CSA treated Wistar rats a...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Fasel J,Kaissling B,Ludwig KS,Ryffel B,Mihatsch MJ

    更新日期:1987-01-01 00:00:00

  • Renal malakoplakia: report of a case with multifocal involvement.

    abstract::The authors report the light microscopic and ultrastructural features in one case of malakoplakia involving the kidney, the urinary bladder, and the skin. The kidney was excised. Lesions of the urinary bladder and the skin regressed after topical treatment with cholinergic agonists and antimicrobial drugs. This case i...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Lloreta J,Cañas MA,Munné A,Arumí M,Bielsa O,Gelabert A,Serrano S

    更新日期:1997-11-01 00:00:00

  • Malignant mesothelioma with intracytoplasmic crystalline inclusions.

    abstract::A 60-year-old female presented with a history of hoarseness, cough, chest pain, and dyspnea and a needle biopsy sample was submitted for histology. Light microscopy showed sheets of tumor cells with eosinophilic cytoplasm containing multiple crystals and eccentrically located nuclei. Electron microscopy showed large i...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Goedhals J,Beukes CA,Cooper S

    更新日期:2007-01-01 00:00:00

  • Neutrophil fate in gingival crevicular fluid.

    abstract::The fate of the neutrophils within the inflammatory exudate in the periodontal crevice and their possible participation in the formation of neutrophil extracellular traps (NETs) are of clinical interest. However, the cytological analysis of clinical samples of inflammatory exudate is restricted by the obtainable quant...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Vitkov L,Klappacher M,Hannig M,Krautgartner WD

    更新日期:2010-02-01 00:00:00

  • Sclerosing stromal tumor of the ovary: an ultrastructural and immunohistochemical analysis with histogenetic considerations.

    abstract::Sclerosing stromal tumors are rare, benign ovarian neoplasms of unknown etiology and histogenesis. Three sclerosing stromal tumors were evaluated by immunohistochemistry and electron microscopy and were compared to two thecomas and nonneoplastic ovarian mesenchymal tissue. The sclerosing stromal tumors and thecomas we...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章


    authors: Shaw JA,Dabbs DJ,Geisinger KR

    更新日期:1992-05-01 00:00:00