Abstract:
OBJECTIVE:Comparative studies of social responsiveness, an ability that is impaired in autism spectrum disorders, can inform our understanding of both autism and the cognitive architecture of social behavior. Because there is no existing quantitative measure of social responsiveness in chimpanzees, we generated a quantitative, cross-species (human-chimpanzee) social responsiveness measure. METHOD:We translated the Social Responsiveness Scale (SRS), an instrument that quantifies human social responsiveness, into an analogous instrument for chimpanzees. We then retranslated this "Chimpanzee SRS" into a human "Cross-Species SRS" (XSRS). We evaluated three groups of chimpanzees (n = 29) with the Chimpanzee SRS and typical and human children with autism spectrum disorder (ASD; n = 20) with the XSRS. RESULTS:The Chimpanzee SRS demonstrated strong interrater reliability at the three sites (ranges for individual ICCs: 0.534 to 0.866; mean ICCs: 0.851 to 0.970). As has been observed in human beings, exploratory principal components analysis of Chimpanzee SRS scores supports a single factor underlying chimpanzee social responsiveness. Human subjects' XSRS scores were fully concordant with their SRS scores (r = 0.976, p = .001) and distinguished appropriately between typical and ASD subjects. One chimpanzee known for inappropriate social behavior displayed a significantly higher score than all other chimpanzees at its site, demonstrating the scale's ability to detect impaired social responsiveness in chimpanzees. CONCLUSION:Our initial cross-species social responsiveness scale proved reliable and discriminated differences in social responsiveness across (in a relative sense) and within (in a more objectively quantifiable manner) human beings and chimpanzees.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Marrus N,Faughn C,Shuman J,Petersen SE,Constantino JN,Povinelli DJ,Pruett JR Jrdoi
10.1016/j.jaac.2011.01.009subject
Has Abstractpub_date
2011-05-01 00:00:00pages
508-18issue
5eissn
0890-8567issn
1527-5418pii
S0890-8567(11)00056-6journal_volume
50pub_type
杂志文章abstract::Although narcolepsy is rarely diagnosed before adulthood, symptoms often begin much earlier and can easily mimic psychiatric disorders in children and adolescents. Clinical experience from a pediatric sleep center is reviewed in 16 consecutive cases of polysomnographically proven narcolepsy with onset of symptoms by a...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199407000-00009
更新日期:1994-07-01 00:00:00
abstract::Sixty-three child and adolescent patients meeting operational criteria for depression and 68 non-depressed child psychiatric controls were followed into adulthood. Twenty-one percent of the depressed group had had conduct disorder (CD) in conjunction with their index depression. Depressed children with comorbid CD did...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199105000-00013
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVES:First, to investigate whether there is covariation between risk behaviors, including suicidality, in a community probability sample of children and adolescents; and second, to investigate whether risk behavior is associated with selected potential correlates. METHOD:A sample of 9- to 17-year-old youths (N =...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1097/00004583-200007000-00017
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:Suicidal behavior and self-harm are common in adolescents and are associated with elevated psychopathology, risk of suicide, and demand for clinical services. Despite recent advances in the understanding and treatment of self-harm and links between self-harm and suicide and risk of suicide attempt, progress i...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jaac.2014.10.009
更新日期:2015-02-01 00:00:00
abstract::Although mental health and correctional programs for juveniles house similar populations, their approaches to behavioral management can be quite different. This difference is evident in the use of isolation and restraint. Both of these interventions are effective behavioral management tools but are subject to abuse if...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199003000-00014
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:To evaluate childhood temperamental traits and early illness experiences in the etiology of adult panic disorder with agoraphobia. METHOD:Evaluated temperamental and illness experience factors, at ages 3 through 18, as predictors of panic and agoraphobia at ages 18 or 21 in an unselected sample (N = 992). An...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200105000-00015
更新日期:2001-05-01 00:00:00
abstract::In a recent review of nonbehavioral child and adolescent psychotherapy, it was concluded that the magnitude of methodological flaws in this body of research precluded an evaluation of effectiveness. However, recent quantitative reviews of child and adolescent therapy have concluded that nonbehavioral therapy is relati...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,meta分析
doi:10.1097/00004583-199207000-00019
更新日期:1992-07-01 00:00:00
abstract::This study is a clinical extension of two previous epidemiological studies on problem behavior in international adoptees. In depth pictures were obtained by clinical interviews of 132 14-year-old international adoptees and their parents. Children were selected on the basis of previously obtained Child Behavior Checkli...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199005000-00014
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:To estimate genetic, environmental, and rater contrast influences on parental reports of Activities, Social, School, and Total Competence scales of the Child Behavior Checklist (CBCL). METHOD:Parents of 492 twin pairs aged 8-12 years completed CBCLs. Genetic, shared and unique environmental, and rater bias e...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200303000-00017
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:To determine the impact of varying attention-deficit/hyperactivity disorder (ADHD) diagnostic criteria, including new DSM-5 criteria, on prevalence estimates. METHOD:Parent and teacher reports identified high- and low-screen children with ADHD from elementary schools in 2 states that produced a diverse overa...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2014.10.014
更新日期:2015-01-01 00:00:00
abstract::Both longitudinal and cross-sectional studies utilizing population and family study samples have found evidence for a secular increase in major affective disorders in adults. Applying techniques used in cross-sectional studies in adults to family study data of children and adolescents, the authors demonstrate evidence...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199207000-00004
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:To explicate differences between early and recent meta-analytic estimates of the effects of cognitive-behavioral therapy (CBT) for adolescent depression. METHOD:Meta-analytic procedures were used to investigate whether methodological characteristics moderated mean effect sizes among 11 randomized, controlled...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,meta分析
doi:10.1097/chi.0b013e3180592aaa
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between components of death concept (preoccupation with death, death as a pleasant state, and death as final) and suicidal behavior in adolescents. METHOD:The death concepts of 51 suicidal inpatients, 102 nonsuicidal inpatients, 36 emergency room suicidal subjects, and 81 norm...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199812000-00011
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVE:To identify approaches to improving methods for assessing tolerability and safety of psychotropic medications in children and adolescents. METHOD:Strengths and limitations of current methodology were reviewed and possible alternatives examined. RESULTS:Research on the validity of safety evaluation has been ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/01.CHI.0000046840.90931.36
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:The association between depression and educational attainment in young people is unclear. This systematic review and meta-analysis examines the longitudinal association between depression and subsequent attainment, and its potential effect modifiers and mediators. METHOD:We searched Embase, PsycINFO, PubMed,...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2020.10.008
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To determine the effectiveness of an intervention designed to improve outcomes for infants and toddlers in foster care. METHOD:Records were reviewed for all children who were adjudicated as in need of care in a specific parish in Louisiana between 1991 and 1998. This period included 4 years before and 4 year...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章
doi:10.1097/00004583-200102000-00016
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the progression in development of moral-emotional responsiveness in children and adolescents and to examine the relationship of this progression with previously identified stages of conceptualization of conscience. METHOD:Using three semistructured questions from the S...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199401000-00017
更新日期:1994-01-01 00:00:00
abstract::Thirty 6- to 9-year-old boys were rated by their mothers and teachers as being pervasively hyperactive, situationally hyperactive, or not hyperactive at home or school. Maternal characteristics and perceptions of their children's behavior problems were collected. Children's global and molecular social skills were also...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199007000-00008
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between time reproduction, performance variability, and sustained attention deficits in children with attention-deficit/hyperactivity disorder (ADHD) combined (ADHD-C) and inattentive (ADHD-I) subtypes, relative to matched controls. METHOD:Participants (age range 7.1-14.1 years) p...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200502000-00009
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:A potentially useful tool for understanding the distribution and determinants of emotional dysregulation in children is a Child Behavior Checklist profile, comprising the Attention Problems, Anxious/Depressed, and Aggressive Behavior clinical subscales (CBCL-DP). The CBCL-DP indexes a heritable trait that inc...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jaac.2011.05.001
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence and correlates of psychiatric disorders among preschool children in a primary care pediatric sample. METHOD:In a two-stage design, 3,860 preschool children were screened; 510 received fuller evaluations. RESULTS:For quantitative assessment of disorder (> or = 90th percentile), pr...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199602000-00014
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVES:To investigate whether a pattern of lower autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis activity is found in children with disruptive behavior disorders (DBD) under nonstressful and stressful conditions, and whether such a pattern would correspond with their feelings of control...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200011000-00019
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that methylphenidate reduces thresholds for reward in children with attention-deficit hyperactivity disorder (ADHD). METHOD:A double-blind crossover design was used in which 16 ADHD boys, aged 8 to 13 years, received methylphenidate on one testing occasion and placebo on another. On ea...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-199507000-00013
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To examine the efficacy of a modular cognitive-behavioral therapy (CBT) protocol relative to treatment as usual (TAU) among children with high-functioning autism spectrum disorders (ASD) and clinically significant anxiety. METHOD:A total of 45 children (7-11 years of age) with high-functioning ASD and clinic...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2012.11.007
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Daily living skills are a predictor of positive outcomes in individuals with autism spectrum disorder (ASD), yet little is known about trajectories of daily living skills in adults with ASD. This study investigated the impact of high school exit on participants' trajectories of daily living skills age equival...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2020.11.008
更新日期:2020-11-17 00:00:00
abstract:OBJECTIVE:To review all literature on the nonmedical use (NMU) and diversion of prescription stimulants to better understand the characteristics, risk factors, and outcomes of NMU and to review risk-reduction strategies. METHOD:We systematically searched PubMed, PsycINFO, and SCOPUS from inception to May 2018 for stud...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2019.06.012
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Children with Pervasive Developmental Disorders (PDDs) have social interaction deficits, delayed communication, and repetitive behaviors as well as impairments in adaptive functioning. Many children actually show a decline in adaptive skills compared with age mates over time. METHOD:This 24-week, three-site,...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jaac.2011.11.010
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To elucidate the effects of tricyclic antidepressants on sympathetic and vagal modulation of heart rate variability. METHOD:Seventy-five children and adolescents (mean age 10.5 years, SD 2.0) from therapeutic and regular schools underwent challenges of paced breathing and orthostatic postural change, while h...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199801000-00017
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To revise and update consensus guidelines for medication treatment algorithms for childhood major depressive disorder based on new scientific evidence and expert clinical consensus when evidence is lacking. METHOD:A consensus conference was held January 13-14, 2005, that included academic clinicians and rese...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 共识发展会议,杂志文章
doi:10.1097/chi.0b013e31804a859b
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:The two primary-seemingly contradictory-strategies for classifying child psychiatric syndromes are categorical and dimensional; conceptual ambiguities appear to be greatest for polythetic syndromes such as autism spectrum disorder (ASD). Recently, a compelling alternative has emerged that integrates both cate...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2018.09.431
更新日期:2019-09-01 00:00:00