Abstract:
OBJECTIVE:To revise and update consensus guidelines for medication treatment algorithms for childhood major depressive disorder based on new scientific evidence and expert clinical consensus when evidence is lacking. METHOD:A consensus conference was held January 13-14, 2005, that included academic clinicians and researchers, practicing clinicians, administrators, consumers, and families. The focus was to review, update, and incorporate the most current data to inform and recommend specific pharmacological approaches and clinical guidance for treatment of major depressive disorder in children and adolescents. RESULTS:Consensually agreed on medication algorithms for major depression (with and without psychosis) and comorbid attention-deficit disorders were updated. These revised algorithms also incorporated approaches to address issues of suicidality, aggression, and irritability. Stages 1, 2, and 3 of the algorithm consist of selective serotonin reuptake inhibitor and norepinephrine serotonin reuptake inhibitor medications whose use is supported by controlled, acute clinical trials and clinical experience. Recent studies provide support that selective serotonin reuptake inhibitors in addition to fluoxetine are still encouraged as first-line interventions. The need for additional assessments, precautions, and monitoring is emphasized, as well as continuation and maintenance treatment. CONCLUSIONS:Evidence and expert clinical consensus support the use of selected antidepressants in the treatment of depression in youths. The use of the recommended antidepressant medications requires appropriate monitoring of suicidality and potential adverse effects and consideration of other evidence-based treatment alternatives such as cognitive behavioral therapies.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Hughes CW,Emslie GJ,Crismon ML,Posner K,Birmaher B,Ryan N,Jensen P,Curry J,Vitiello B,Lopez M,Shon SP,Pliszka SR,Trivedi MH,TEXAS CONSENSUS CONFERENCE PANEL ON MEDICATION TREATMENT OF CHILDHOOD MAJOR DEPRESSIVE DISORDER.doi
10.1097/chi.0b013e31804a859bsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
667-686issue
6eissn
0890-8567issn
1527-5418pii
S0890-8567(09)62147-Xjournal_volume
46pub_type
共识发展会议,杂志文章abstract:OBJECTIVE:To clarify the relationship between scales and structured diagnostic interview diagnoses, the authors used a two-stage screening method to study 201 military families with one or more children ages 5 to 17. METHOD:Parents and children were interviewed with the Diagnostic Interview Schedule for Children (DISC...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199303000-00022
更新日期:1993-03-01 00:00:00
abstract::Bullying is a global phenomenon with significant mental health consequences. Although bullying prevention programs have garnered attention over the last several years, the results of these programs have been mixed, at best. As Koyanagi et al.1 highlight in this issue of the Journal, the consequences of bullying can be...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 评论,社论
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更新日期:2019-09-01 00:00:00
abstract::New findings are presented from a survey of depressive symptoms, illicit drug use, and suicidality among 4,157 adolescents attending school in six border cities in Texas and neighboring Tamaulipas, Mexico. Among the Texas youth, 48.08% scored above 16 on the Center for Epidemiologic Studies' Depression Scale (CES-D); ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199207000-00014
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:Because ADHD is heterogeneous with respect to psychiatric comorbidity, familiality, and learning disabilities, it was hypothesized that such features might influence the severity and pattern of neuropsychological function in ADHD. METHOD:Subjects were 9- to 20-year-old males with DSM-III-R ADHD (n = 65) and ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199508000-00011
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:This study examined the familial relationship between Gilles de la Tourette's syndrome (GTS) and attention deficit disorder (ADD), learning problems, speech disorders, and stuttering. METHOD:This family study consisted of 338 first degree relatives of 85 GTS probands and 113 controls. All available relatives...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199309000-00025
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:Although the combination of methylphenidate (MPH) and behavior modification (BMOD) has been advocated to enhance clinical outcome for children with attention-deficit hyperactivity disorder (ADHD) and comorbid disruptive disorders, few group studies have been conducted. This study evaluates the separate and in...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-199905000-00020
更新日期:1999-05-01 00:00:00
abstract::A twin study examines the relationship of affect attunement to four factors of development: zygosity, temperament, attachment, and twin preference. Affect attunement occurs when an infant expresses affect and a mother responds cross-modally, matching duration, intensity, and rhythm. A sample of 16, same sex, healthy t...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-198903000-00017
更新日期:1989-03-01 00:00:00
abstract:OBJECTIVE:This study examined the 7-year outcome of speech/language (S/L) impaired and control children selected from a community sample at age 5 years. METHOD:Two hundred fifteen children completed a variety of speech and language tests at age 12 years. Children with S/L impairment were further classified as "speech ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-199411000-00015
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVE:To examine whether first-episode psychosis patients with onset during adolescence (ages 15-18) differ significantly from those with young-adult onset (ages 19-30). METHOD:Consecutive patients presenting with first-episode psychosis (N = 242) were assessed for demographic and illness characteristics such as d...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.chi.0000164591.55942.ea
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:Child maltreatment is associated with dysregulation of stress-mediating systems and an increased risk of mental and physical health problems. Specifically, disruptions in hypothalamic-pituitary-adrenal (HPA) axis regulation have been reported in maltreated children. The current study investigates whether incr...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2014.08.006
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Conduct problems and hyperactivity are frequent among children referred for sleep-disordered breathing (SDB), restless legs syndrome, or periodic leg movements during sleep (PLMS), but children not referred to sleep centers have received little study. METHOD:Parents of children aged 2 to 14 years were survey...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200302000-00014
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:The course of obsessive-compulsive disorder (OCD) in childhood and adolescence was analyzed. METHOD:Twenty-three (88%) of 26 children and adolescents with OCD, all referred to a county child psychiatric clinic as inpatients or outpatients, were longitudinally evaluated every 6 months for obsessive-compulsive...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199511000-00009
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:To review evidence for the neurodevelopmental effects of in utero exposure to nicotine. Concerns about long-term cognitive and behavioral effects of prenatal exposure to nicotine arise from reports of increased rates of disruptive behavioral disorders in children whose mothers smoked during pregnancy. The rel...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-200106000-00007
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:Neuroimaging studies have identified distinct neural correlates of obsessive-compulsive disorder (OCD) symptom dimensions in adult subjects and may be related to functional abnormalities in different cortico-striatal-thalamic neural systems underlying cognition and affective processing. Similar symptom dimens...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e3181b2163c
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To study whether prenatal smoking only relates to externalizing problems or whether it is associated with both internalizing and externalizing problems from childhood into late adolescence. METHOD:Child Behavior Checklist-derived, parent-reported internalizing and externalizing problems of 396 children were ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e318172eefb
更新日期:2008-07-01 00:00:00
abstract::Twenty-seven children (or smaller subgroups depending upon task difficulty and subject ability) with subaverage IQs took part in a double-blind, placebo-controlled, cross-over study of methylphenidate (0.4 mg/kg/day) and thioridazine (1.75 mg/kg/day). The children were tested for IQ performance, breadth of attention, ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-09-01 00:00:00
abstract::Adolescent suicide attempts are often impulsive. It has been suggested that individuals who make nonimpulsive (premeditated) attempts have greater suicidal intent and are more hopeless than the impulsive attempters. Eighty-six adolescent suicide attempters were categorized according to the degree of premeditation of t...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199101000-00014
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To evaluate empirically the implications of choosing different thresholds to classify conduct disorder and attention-deficit hyperactivity disorder for estimating prevalence, test-retest reliability of measurement, and informant (parent/teacher) agreement and for evaluating comorbidity and associated features...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
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journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1097/00004583-200007000-00017
更新日期:2000-07-01 00:00:00
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journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199701000-00016
更新日期:1997-01-01 00:00:00
abstract::This summary is presented as a guide for clinicians evaluating the often delicate and complex issues surrounding a child custody dispute. The historical basis of child custody and the various judicial presumptions that have guided courts, as well as the differences between performing child custody evaluation and engag...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199712000-00034
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To assess critically the short-term efficacy and safety of carbamazepine in the reduction of aggressiveness in children with diagnosed conduct disorder. METHOD:Subjects were children aged 5 to 12 years who were hospitalized for treatment-resistant aggressiveness and explosiveness and who had diagnosed conduc...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-199604000-00014
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between psychiatric disorder and psychological characteristics at 6-year follow-up of adolescent-onset anorexia nervosa. METHOD:Twenty-three subjects were interviewed by telephone using the Structured Clinical Interview for DSM-III-R diagnosis. These subjects and 23 demographicall...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199311000-00018
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:To compare the familial clustering of affective disorders among first-degree relatives of prepubertal versus adult probands with mood disorders. METHOD:The Family History-Research Diagnostic Criteria (FH-RDC) assessment instrument was used to obtain data on first-degree relatives of all probands. Logistic re...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199704000-00008
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:To examine the hypothesis that autism spectrum disorders (ASD) diagnosis and traits in childhood are associated with suicidal thoughts, plans and self-harm at 16 years, and that any observed associations are explained by depression at 12 years. METHOD:We examined associations between ASD diagnosis and 4 dich...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2018.01.023
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To examine the effect of sex, latitude, and behavior problems on symptoms related to pediatric seasonal affective disorder among seventh and ninth graders. METHOD:A school survey including a modified version of the Seasonal Pattern Assessment Questionnaire was carried out in 2 Finnish cities located in the 6...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199910000-00016
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:Family interventions have been found to be effective in pediatric bipolar disorder (BD). This study examined the moderating effects of parental expressed emotion (EE) on the 2-year symptomatic outcomes of adolescent BD patients assigned to family-focused therapy for adolescents (FFT-A) or a brief psychoeducat...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/CHI.0b013e3181a0ab9d
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:The present study examined the factor structure of autism symptoms in toddlers, to aid understanding of the phenotype during the developmental period that represents the earliest manifestations of autism symptoms. This endeavor is particularly timely, given changes in symptom structure from the Diagnostic and...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2013.05.004
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To describe the rationale, methodology, and sample characteristics of a dual-site treatment study (New York and Montreal) of children with attention-deficit/hyperactivity disorder (ADHD) conducted between 1990 and 1995. The hypotheses were that (1) methylphenidate combined with comprehensive multimodal psycho...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.chi.0000128798.91601.fe
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:The Collaborative Life Skills (CLS) program is a school-home intervention for students with attention-deficit/hyperactivity disorder (ADHD) symptoms and impairment. CLS integrates school, parent, and student treatments followed by booster sessions during a maintenance period into the subsequent school year. ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2018.01.016
更新日期:2018-04-01 00:00:00