Abstract:
OBJECTIVE:To describe the rationale, methodology, and sample characteristics of a dual-site treatment study (New York and Montreal) of children with attention-deficit/hyperactivity disorder (ADHD) conducted between 1990 and 1995. The hypotheses were that (1) methylphenidate combined with comprehensive multimodal psychosocial treatment was superior to methylphenidate alone in improving multiple functions and (2) the efficacy of the psychosocial intervention resulted from its specific components and not from nonspecific treatment effects. METHOD:One hundred three children with ADHD (ages 7-9), free of conduct and learning disorders, who responded to methylphenidate, were randomized for 2 years to (1) methylphenidate treatment alone; (2) methylphenidate combined with multimodal psychosocial treatment that included parent training and counseling, academic assistance, psychotherapy, and social skills training; or (3) methylphenidate plus attention control treatment that excluded specific aspects of the psychosocial intervention. Children were switched to single-blind placebo after 12 months; methylphenidate was reinstituted when clinically indicated. Assessments included ratings by parents, teachers, children, and psychiatrists; school observations in academic and gym classes; and academic performance tests. Almost 80% of families completed the 2-year study. Companion papers present treatment effects. CONCLUSIONS:A comprehensive 2-year psychosocial treatment was delivered successfully to children with ADHD and their families.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Klein RG,Abikoff H,Hechtman L,Weiss Gdoi
10.1097/01.chi.0000128798.91601.fesubject
Has Abstractpub_date
2004-07-01 00:00:00pages
792-801issue
7eissn
0890-8567issn
1527-5418pii
S0890-8567(09)61397-6journal_volume
43pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:To characterize the structural and functional neurobiology of a large group of adolescents exhibiting a behaviorally and emotionally dysregulated phenotype. METHOD:Adolescents aged 14 years from the IMAGEN study were investigated. Latent class analysis (LCA) on the Strengths and Difficulties Questionnaire (S...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2019.01.021
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To estimate genetic, environmental, and rater contrast influences on parental reports of Activities, Social, School, and Total Competence scales of the Child Behavior Checklist (CBCL). METHOD:Parents of 492 twin pairs aged 8-12 years completed CBCLs. Genetic, shared and unique environmental, and rater bias e...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200303000-00017
更新日期:2003-03-01 00:00:00
abstract::The clinical guidance based on the research article, "Specific Components of Pediatricians' Medication-Related Care Predict Attention-Deficit/Hyperactivity Disorder Improvement," published in the June 2017 issue,1 might be premature. The authors, Epstein et al., suggest that "Physicians do not need to necessarily rely...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 信件
doi:10.1016/j.jaac.2018.02.015
更新日期:2018-06-01 00:00:00
abstract::The present study examined prevalence, expression, and developmental patterns of DSM-III-R anxiety disorder symptoms in 62 never-psychiatrically-ill children. Subclinical phobias and overanxious disorder symptoms were fairly common, while symptoms of other anxiety disorders were less common. Direction of sex and age d...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199009000-00014
更新日期:1990-09-01 00:00:00
abstract::One hundred and seventeen biological mothers and 63 biological fathers of depressed and nondepressed, psychiatrically disturbed children and adolescents were interviewed with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version. Diagnostic information was also obtained on 54 biological fathers who w...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-198905000-00008
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVE:Youths with euthymic bipolar disorder (BD) have a deficit in face-emotion labeling that is present across multiple emotions. Recent research indicates that youths at familial risk for BD, but without a history of mood disorder, also have a deficit in face-emotion labeling, suggesting that such impairments may...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e318188832e
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To determine the impact of a parent education and behavior management intervention (PEBM) on the mental health and adjustment of parents with preschool children with autism. METHOD:A randomized, group-comparison design involving a parent education and counseling intervention to control for nonspecific therap...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/01.chi.0000205701.48324.26
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:Research Domain Criteria (RDoC) operationalizes a set of basic social dimensions that can be used to deconstruct sources of variation in social impairments across affected individuals, regardless of their diagnostic status. This is a necessary step toward the development of etiologically based and individuali...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2019.07.938
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:To design a treatment manual and adherence measure for attachment-based family therapy (ABFT) for adolescent depression and to collect pilot data on the treatment's efficacy. METHOD:Over a period of 2 years, 32 adolescents meeting criteria for major depressive disorder (MDD) were randomly assigned to 12 week...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-200210000-00008
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:Both the diagnosis and treatment of bipolar disorder in youth remain the subject of debate. In the Treatment of Early Age Mania (TEAM) study, risperidone was more effective than lithium or divalproex in children diagnosed with bipolar mania and highly comorbid with attention-deficit/hyperactivity disorder (AD...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jaac.2012.07.001
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:Clinicians and researchers debate whether children with chronic, nonepisodic irritability should receive the diagnosis of bipolar disorder (BD). To address this debate, we evaluated cognitive flexibility, or the ability to adapt to changing contingencies, in three groups of children: narrow-phenotype BD (NP-B...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/chi.0b013e31802d0b3d
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To compare the level of negative emotions-anxiety, depression, aggression, and impulsivity-in hospitalized adolescents with a history of either a single or multiple suicide attempts. METHOD:Thirty-two adolescents hospitalized for a first suicide attempt, 19 hospitalized for a repeated attempt (fifth or more)...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199805000-00011
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To assess psychiatric impairment and childhood victimization experiences in female child molesters. METHOD:Eleven incarcerated female child molesters were compared to 11 women imprisoned for nonsexual offenses as to their psychiatric diagnoses based on interviews with the Structured Clinical Interview for DS...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199409000-00004
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:An alternative set of criteria for posttraumatic stress disorder (PTSD) for preschool children was analyzed for validity. METHOD:Sixty-two traumatized children and 63 healthy controls, aged 20 months through 6 years, were assessed. The traumatic experiences included motor vehicle collisions, accidental injur...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.CHI.0000046822.95464.14
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:Although clinical studies have demonstrated smaller subcortical volumes in structures such as the amygdala, hippocampus, caudate nucleus, and thalamus in adults and adolescents with depressive disorders and anxiety, no study has assessed such structures in babies, long before the development of the disorders....
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2010.07.003
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:We conducted a 1-year prospective follow-up study of posttreatment clinical outcomes in adolescents with recent and repetitive self-harm who had been randomly allocated to receive 19 weeks of either dialectical behavior therapy adapted for adolescents (DBT-A) or enhanced usual care (EUC) at community child an...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2016.01.005
更新日期:2016-04-01 00:00:00
abstract::A case highlighting the association of epilepsy with psychopathology is reported. The patient suffered a rare and extreme behavioral disturbance, characterized by persistent disruptive behavior and intermittent bizarre and violent outbursts. These outbursts often appeared purposeful, but some of them were later diagno...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199810000-00019
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:A prominent noncore symptom of autistic disorder is disturbed sleep, but relatively few studies have investigated this symptom. METHOD:A multimethod approach assessed the quantity and quality of sleep in 194 children (68 with autism [AUT], 57 with developmental delay without autism [DD], 69 with typical deve...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.ObO13e3181799f7c
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:Most research on irritability and child psychopathology has focused on depressive disorders, bipolar disorder, and/or oppositional defiant disorder (ODD). Less is known about relationships between child anxiety and irritability and moderators of such associations. METHOD:Structural equation modeling (SEM) wa...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2015.10.007
更新日期:2016-01-01 00:00:00
abstract::Videotaped interrater reliability was assessed with the K-SADS-III-R on 25 children with a mean age of 10:9. Kappa statistics were computed in syndromes with a frequency rate of at least 20%. The following mean kappas were obtained: major depression = 0.83; overanxious disorder = 0.85; separation anxiety = 0.85; simpl...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-198909000-00013
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVE:To report results of the clinical reappraisal study of lifetime DSM-IV diagnoses based on the fully structured lay-administered World Health Organization Composite International Diagnostic Interview (CIDI) Version 3.0 in the U.S. National Comorbidity Survey Replication Adolescent Supplement (NCS-A). METHOD:B...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e31819a1cbc
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To examine the prevalence of encopresis/enuresis, relationship between maternal hostility and encopresis, parent-child concordance of reporting encopresis/enuresis, and familial aggregation of enuresis in subjects with a prepubertal and early adolescent bipolar-I disorder phenotype (PEA-BP), attention-deficit...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章
doi:10.1097/01.chi.0000172554.26349.dd
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:The goals of this study were (1) to determine the prevalence of child maltreatment in hospitalized children and adolescents with developmental disabilities and concomitant psychiatric disorders, and (2) to identify the contribution of specific mother and child characteristics to the use of more severe discipl...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199405000-00015
更新日期:1994-05-01 00:00:00
abstract::Few studies have followed young people with autism spectrum disorder (shortened to "autism" herein) over time, and all previous longitudinal studies have used clinical or center-based samples,1,2 leaving considerable uncertainty about the course of autism in the general population. In this issue, Simonoff and colleagu...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 社论
doi:10.1016/j.jaac.2020.06.011
更新日期:2020-12-01 00:00:00
abstract::Enuresis is a symptom that is frequently encountered in child psychiatric evaluations. Careful assessment is required to identify specific urologic, developmental, psychosocial, and sleep-related etiologies. For most children with enuresis, however, a specific etiology cannot be determined. Treatment then involves sup...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200401000-00029
更新日期:2004-01-01 00:00:00
abstract::All outcome studies of child and adolescent residential treatment and inpatient psychiatric hospitalization reported in the literature from 1975 to the present were examined. A set of statistical procedures was developed to integrate the findings of the 34 studies, which provided a weighted predictive value for 10 var...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199011000-00001
更新日期:1990-11-01 00:00:00
abstract::Functional dysphagia in children has historically been treated using a cognitive behavioral approach. The case of a 7-year-old boy treated using a successful multimodal approach, including behavioral, family, and play therapy with alprazolam augmentation, is reported. The patient showed minimal response to early inter...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199409000-00012
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:This national study examined the practices and perceptions of smoking cessation activities among child and adolescent psychiatrists. METHOD:A random sample of child and adolescent psychiatrists was identified from the membership list of the American Academy of Child and Adolescent Psychiatry and was mailed a...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.chi.0000242246.07797.c3
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To examine the influence of development and gender on the pharmacokinetics of desipramine (DMI) in the pediatric population. METHOD:DMI pharmacokinetic parameters were calculated from 407 routinely drawn, dose- and weight-normalized serum concentrations in 173 youths receiving DMI (90 children, 83 adolescent...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199901000-00023
更新日期:1999-01-01 00:00:00
abstract::Lesbian, gay, bisexual, and transgender (LGBT) youth have unique medical and mental health needs. Exposure to stigma such as family non-acceptance is associated with adverse mental health outcomes that are important sources of morbidity and mortality in this population. These include depression, anxiety, substance abu...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 社论
doi:10.1016/j.jaac.2019.02.009
更新日期:2019-07-01 00:00:00