Abstract:
OBJECTIVE:To compare the familial clustering of affective disorders among first-degree relatives of prepubertal versus adult probands with mood disorders. METHOD:The Family History-Research Diagnostic Criteria (FH-RDC) assessment instrument was used to obtain data on first-degree relatives of all probands. Logistic regression was used to assess the strength of the age of the proband to predict FH-RDC diagnoses in relatives. Survival analysis was used to examine the age-at-onset distribution of first FH-RDC diagnosis while controlling for year of birth. RESULTS:The prevalence of major affective disorders was more than two times higher among first-degree relatives of child probands versus those of adult probands even when controlling for birth cohort. Cumulative risk for lifetime major mood disorders in first-degree relatives of child probands was significantly higher than for those of adult probands. CONCLUSION:These analyses further support that ascertainment of families through affected children identifies pedigrees with a higher proportion of affected relatives than ascertainment through affected adults.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Neuman RJ,Geller B,Rice JP,Todd RDdoi
10.1097/00004583-199704000-00008subject
Has Abstractpub_date
1997-04-01 00:00:00pages
466-73issue
4eissn
0890-8567issn
1527-5418pii
S0890-8567(09)62516-8journal_volume
36pub_type
杂志文章abstract:OBJECTIVE:To determine whether adolescents with major depressive disorder have disturbances in their cellular immunity and to study whether the immunological changes detected are specific to depression or are general responses to stress. METHOD:Twenty subjects with major depressive disorder, 17 nondepressed subjects w...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199406000-00008
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVES:To investigate whether a pattern of lower autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis activity is found in children with disruptive behavior disorders (DBD) under nonstressful and stressful conditions, and whether such a pattern would correspond with their feelings of control...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200011000-00019
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To compare clinical characteristics of hospitalized adolescents who (1) have recently made their first suicide attempt, (2) have recently made a second or subsequent attempt, (3) have made previous but no recent attempts, or (4) have never made an attempt. METHOD:Semistructured psychiatric diagnostic intervi...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199605000-00018
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:Previous studies indicate that low resting heart rate is probably the best-replicated biological correlate of childhood antisocial and aggressive behavior. Nevertheless, there have been few longitudinal tests of this relationship, little control over potential confounds and mediators, and no test of its cross...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199710000-00029
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:Younger siblings of children with autism spectrum disorder (ASD) are at high risk (HR) for developing ASD as well as features of the broader autism phenotype. Although this complicates early diagnostic considerations in this cohort, it also provides an opportunity to examine patterns of behavior associated sp...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jaac.2014.09.015
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To develop a reliable and valid child and parent self-report instrument to screen children with anxiety disorders. METHOD:An 85-item questionnaire was administered to 341 outpatient children and adolescents and 300 parents. Utilizing item analyses and factor analyses, the original scale was reduced to 38 ite...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199704000-00018
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:Clinical research depends on the participation of representative samples. At the 2001 Annual Meeting of the American Academy of Child and Adolescent Psychiatry, the Workgroup on Research conducted a research forum with the purpose of improving recruitment and retention of children and adolescents in research ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type:
doi:10.1097/01.chi.0000129222.89433.3d
更新日期:2004-08-01 00:00:00
abstract::This summary is presented as a guide for clinicians evaluating the often delicate and complex issues surrounding a child custody dispute. The historical basis of child custody and the various judicial presumptions that have guided courts, as well as the differences between performing child custody evaluation and engag...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199712000-00034
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:Over half of the world's refugee population are under the age of 18 years. This systematic review aims to summarize the current body of evidence for the prevalence of mental illness in child and adolescent refugee populations. METHOD:Eight electronic databases, gray literature, and Google Scholar were search...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2019.11.011
更新日期:2020-06-01 00:00:00
abstract::Bullying is a global phenomenon with significant mental health consequences. Although bullying prevention programs have garnered attention over the last several years, the results of these programs have been mixed, at best. As Koyanagi et al.1 highlight in this issue of the Journal, the consequences of bullying can be...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 评论,社论
doi:10.1016/j.jaac.2019.04.007
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To examine the cognitive/affective and behavioral symptoms of adolescent suicide attempters with self-mutilative behavior (SMB). METHOD:Adolescents evaluated after a suicide attempt that occurred between 1996 and 2000 were divided into two groups: suicide attempters with a history of SMB (n = 52) and suicide...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200109000-00015
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVE:To test the reliability and validity of DSM-IV oppositional defiant and conduct disorders (ODD and CD) and symptoms using the Kiddie Disruptive Behavior Disorders Schedule and generate data on the manifestation of symptoms of ODD and CD in 3- to 5-year-old children. METHOD:One hundred twenty-three consecutiv...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e31803062d3
更新日期:2007-04-01 00:00:00
abstract::The period spanning late childhood and early adulthood is of critical importance to mental health. This is a time of extensive brain reorganization, driven by interactions between environmental exposures, changes in the social role of individuals, and biologically programmed processes, which sets the foundation for ad...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 评论,社论
doi:10.1016/j.jaac.2019.03.010
更新日期:2019-11-01 00:00:00
abstract::Part II of this review critically evaluates antidepressants' (AD) efficacy in children and adolescents with anxiety, physical, and behavioral disorders as well as AD's side-effect spectrum. AD are administered increasingly to youths with specific anxiety syndromes phenomenologically paralleling those in adults which a...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199305000-00001
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:The cost-effectiveness of three active interventions for major depression in adolescents was compared after 36 weeks of treatment in the Treatment of Adolescents with Depression Study. METHOD:Outpatients aged 12 to 18 years with a primary diagnosis of major depression participated in a randomized controlled ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/CHI.0b013e3181a2b319
更新日期:2009-07-01 00:00:00
abstract::The prevalence of substance abuse and coexisting DSM-III psychiatric disorders was evaluated in 111 juvenile offenders. As expected, a high rate of conduct disorder (91%) was present in both substance abusing and nonsubstance abusing juvenile offenders. However, significantly higher rates of attention deficit disorder...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199107000-00007
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To describe program outcomes for the Combined Training Program in Child and Adolescent Psychiatry, Pediatrics, and Psychiatry (Triple Board Program). METHOD:All Triple Board Program graduates to date (1991-2003) were asked to participate in a 37-item written survey from February to April 2004. RESULTS:The r...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.chi.0000214190.80863.05
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To investigate abnormalities of thalamocortical and intrathalamic functional connectivity (FC) in children with primary nocturnal enuresis (PNE) during light non-rapid eye movement (NREM) sleep using a simultaneous electroencephalography (EEG)-functional magnetic resonance imaging (fMRI) method. METHOD:Polys...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2019.05.028
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Abnormal stereotyped behaviors are a significant problem for many individuals with mental retardation or mental illness. To increase understanding of the development of abnormal stereotyped behaviors, the authors investigated the early rhythmic behaviors of children at increased risk for developmental delays....
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200201000-00013
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:Children with Pervasive Developmental Disorders (PDDs) have social interaction deficits, delayed communication, and repetitive behaviors as well as impairments in adaptive functioning. Many children actually show a decline in adaptive skills compared with age mates over time. METHOD:This 24-week, three-site,...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jaac.2011.11.010
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To examine the efficacy of a modular cognitive-behavioral therapy (CBT) protocol relative to treatment as usual (TAU) among children with high-functioning autism spectrum disorders (ASD) and clinically significant anxiety. METHOD:A total of 45 children (7-11 years of age) with high-functioning ASD and clinic...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2012.11.007
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To assess the presence of traits of separation anxiety disorder in boys referred clinically for gender identity disorder. METHOD:One hundred fifteen boys were referred to a specialty clinic for concerns about their gender identity development. They were divided into two subgroups: one group met the complete ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199606000-00019
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:A potentially useful tool for understanding the distribution and determinants of emotional dysregulation in children is a Child Behavior Checklist profile, comprising the Attention Problems, Anxious/Depressed, and Aggressive Behavior clinical subscales (CBCL-DP). The CBCL-DP indexes a heritable trait that inc...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jaac.2011.05.001
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:Because ADHD is heterogeneous with respect to psychiatric comorbidity, familiality, and learning disabilities, it was hypothesized that such features might influence the severity and pattern of neuropsychological function in ADHD. METHOD:Subjects were 9- to 20-year-old males with DSM-III-R ADHD (n = 65) and ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199508000-00011
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:To assess the course and outcome of anorexia nervosa (AN) and bulimia nervosa (BN) at a median of 90 months of follow-up in a large cohort of women with eating disorders. METHOD:A prospective, naturalistic, longitudinal design was used to map the course of AN and BN in 246 women. Follow-up data are presented...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199907000-00012
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:Disruptive mood dysregulation disorder (DMDD) is a new diagnosis in the DSM-5. Youth with a family history of bipolar disorder (BD) are at increased risk for BD and non-bipolar psychopathology. No studies to date have examined rates of DMDD among offspring of parents with BD. This study examines the risk for ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2013.12.026
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To evaluate whether including children with onset of symptoms between ages 7 and 12 years in the ADHD diagnostic category would: (a) increase the prevalence of the disorder at age 12, and (b) change the clinical and cognitive features, impairment profile, and risk factors for ADHD compared with findings in th...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:The authors examined the applicability of personality disorder criteria to adolescent inpatients by evaluating internal consistency and criterion overlap. METHOD:Thirty-eight adolescents and 28 adults were assessed with the Personality Disorder Examination. Within-category cohesiveness (internal consistency)...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章
doi:10.1097/00004583-199902000-00020
更新日期:1999-02-01 00:00:00
abstract::This study is a clinical extension of two previous epidemiological studies on problem behavior in international adoptees. In depth pictures were obtained by clinical interviews of 132 14-year-old international adoptees and their parents. Children were selected on the basis of previously obtained Child Behavior Checkli...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199005000-00014
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:Although clinical studies have demonstrated smaller subcortical volumes in structures such as the amygdala, hippocampus, caudate nucleus, and thalamus in adults and adolescents with depressive disorders and anxiety, no study has assessed such structures in babies, long before the development of the disorders....
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2010.07.003
更新日期:2010-10-01 00:00:00