Abstract:
:Both longitudinal and cross-sectional studies utilizing population and family study samples have found evidence for a secular increase in major affective disorders in adults. Applying techniques used in cross-sectional studies in adults to family study data of children and adolescents, the authors demonstrate evidence of a parallel secular increase for child and adolescent onset affective disorders. Normal and depressed prepubertal probands were identified. All full siblings were directly interviewed for lifetime episodes of affective disorder. Analysis of the siblings (probands not further analyzed in this article) by the Cox proportional hazards model demonstrates that the risk for affective disorder is higher in siblings born more recently.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Ryan ND,Williamson DE,Iyengar S,Orvaschel H,Reich T,Dahl RE,Puig-Antich Jdoi
10.1097/00004583-199207000-00004subject
Has Abstractpub_date
1992-07-01 00:00:00pages
600-5issue
4eissn
0890-8567issn
1527-5418pii
S0890-8567(09)64073-9journal_volume
31pub_type
杂志文章abstract::The sudden death of three children receiving the tricyclic antidepressant medication desipramine for behavioral disorders was reported in 1990. We now provide new information about these children and describe a fourth case. Because desipramine is a useful medication for many children, these deaths pose clinical dilemm...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199307000-00013
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVE:Measurement of treatment outcomes in childhood depression has traditionally focused on assessing symptoms from the clinician's perspective, without exploring other outcome domains or considering young people's perspectives. This systematic review explored the extent to which multidimensional and multi-informa...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2018.07.893
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To examine trends in the use of antipsychotic medication in Medicaid-eligible youth from 2008 to 2013 and the factors associated with this use. METHOD:Youth aged 0 to 17 years with at least one claim indicating antipsychotic medication use were identified from the network of a behavioral health managed care ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2016.10.005
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility and effectiveness of a school-based group cognitive-behavioral treatment (CBT) for anxiety disorders with African-American adolescents. METHOD:Twelve adolescents (mean age = 15.6 years) with anxiety disorders were randomly assigned to CBT (n = 6) or a group attention-support contr...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-200207000-00007
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:To conduct the first meta-analysis evaluating the internal and external validity of the sluggish cognitive tempo (SCT) construct as related to or distinct from attention-deficit/hyperactivity disorder (ADHD) and as associated with functional impairment and neuropsychological functioning. METHOD:Electronic da...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jaac.2015.12.006
更新日期:2016-03-01 00:00:00
abstract::New findings are presented from a survey of depressive symptoms, illicit drug use, and suicidality among 4,157 adolescents attending school in six border cities in Texas and neighboring Tamaulipas, Mexico. Among the Texas youth, 48.08% scored above 16 on the Center for Epidemiologic Studies' Depression Scale (CES-D); ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199207000-00014
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:Co-occurrence of psychiatric disorders was investigated among 52 adolescent substance abusers and 23 non-substance-abusing adolescents with conduct and/or oppositional defiant disorders, admitted to the same inpatient facility. METHOD:During independent face-to-face interviews with parent(s) or caretaker(s) ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199405000-00005
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:The objective of this study is to test whether the presence of childhood onset affective disorder identifies families with increased incidence and severity of affective disorders. METHOD:Family history information was collected on the first and second degree relatives and first cousins age > or = 15 years of...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199311000-00008
更新日期:1993-11-01 00:00:00
abstract::Although many adolescent psychiatric patients drink and use drugs, not all engage in problematic behaviors or experience social difficulties while intoxicated. The goal of this study was to identify characteristics of adolescent psychiatric patients for whom intoxication leads to behavioral, social, and medical proble...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199211000-00005
更新日期:1992-11-01 00:00:00
abstract::This study showed that children and adolescents with inflammatory bowel disease (IBD) had a more external locus of control than did matched diabetic and healthy children. An external locus of control correlated with severity of physical illness and presence of psychiatric disorders. It also correlated significantly wi...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199111000-00008
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:To examine the prevalence of infant-toddler social-emotional and behavioral problems and associations with social-emotional competence, interference in family life, and parental worry. METHOD:The sample consisted of 1- and 2-year-old children (mean [MN] age = 24.8 months) from the baseline survey of a repres...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200107000-00016
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:This study measured satisfaction of US and Canadian child psychiatrists with quality of care in their field and behaviors of their payers. METHOD:US and Canadian child psychiatrists were surveyed concerning time spent on billing paperwork, waiting times for psychiatrist reimbursement and patient treatment, a...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199510000-00018
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:To compare mother-child interactions and parenting styles in families of children with major depressive disorder, youths at high risk for depression, and healthy controls. METHOD:Currently depressed (n = 43), high-risk (n = 28), and healthy control (n = 41) youths and their mothers engaged in a standardized ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e3181676595
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:Deficits in cognitive flexibility and response inhibition have been linked to perturbations in cortico-striatal-thalamic circuitry in adult obsessive-compulsive disorder (OCD). Although similar cognitive deficits have been identified in pediatric OCD, few neuroimaging studies have been conducted to examine it...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2010.05.006
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To examine the influence of development and gender on the pharmacokinetics of desipramine (DMI) in the pediatric population. METHOD:DMI pharmacokinetic parameters were calculated from 407 routinely drawn, dose- and weight-normalized serum concentrations in 173 youths receiving DMI (90 children, 83 adolescent...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199901000-00023
更新日期:1999-01-01 00:00:00
abstract::"Behavioral inhibition to the unfamiliar" is a temperamental construct reflecting the tendency to be shy, timid, and constrained in novel situations. Previous work has suggested that it may be associated with anxiety disorders in children. Psychopathology was assessed in children from a nonclinical sample originally i...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199201000-00016
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:Although clinical studies have demonstrated smaller subcortical volumes in structures such as the amygdala, hippocampus, caudate nucleus, and thalamus in adults and adolescents with depressive disorders and anxiety, no study has assessed such structures in babies, long before the development of the disorders....
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2010.07.003
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:Parent training is recommended for attention-deficit/hyperactivity disorder (ADHD) in preschool children. Evidence-based interventions are important, but only if they produce better outcomes than usual care. METHOD:The authors conducted a multicenter, 2-arm, parallel-group, randomized controlled trial in rou...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2018.04.014
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:This study was carried out to examine the efficacy of a 12-week, low-intensity (1-hour/wk of therapist contact), parent-delivered intervention for toddlers at risk for autism spectrum disorders (ASD) aged 14 to 24 months and their families. METHOD:A randomized controlled trial involving 98 children and famil...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2012.08.003
更新日期:2012-10-01 00:00:00
abstract::Despite recent reports that clozapine is useful for the treatment of chronic schizophrenics resistant to neuroleptics, no studies have been reported in adolescents with schizophrenia. Despite the risk of potentially fatal agranulocytosis, clozapine's use in adolescents may become important because of its lack of extra...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199201000-00024
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To determine whether adolescents with major depressive disorder have disturbances in their cellular immunity and to study whether the immunological changes detected are specific to depression or are general responses to stress. METHOD:Twenty subjects with major depressive disorder, 17 nondepressed subjects w...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199406000-00008
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:Deficits in executive function (EF) are common in neuropsychiatric disorders, but the specificity of these deficits remains unclear. The aim of the present study was to elucidate the pattern of EF impairment across psychopathologies in children and adolescents. Associations among components of EF with dimensi...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2017.08.016
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:The cost-effectiveness of three active interventions for major depression in adolescents was compared after 36 weeks of treatment in the Treatment of Adolescents with Depression Study. METHOD:Outpatients aged 12 to 18 years with a primary diagnosis of major depression participated in a randomized controlled ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/CHI.0b013e3181a2b319
更新日期:2009-07-01 00:00:00
abstract::Thirty 6- to 9-year-old boys were rated by their mothers and teachers as being pervasively hyperactive, situationally hyperactive, or not hyperactive at home or school. Maternal characteristics and perceptions of their children's behavior problems were collected. Children's global and molecular social skills were also...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199007000-00008
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:To revise and update consensus guidelines for medication treatment algorithms for childhood major depressive disorder based on new scientific evidence and expert clinical consensus when evidence is lacking. METHOD:A consensus conference was held January 13-14, 2005, that included academic clinicians and rese...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 共识发展会议,杂志文章
doi:10.1097/chi.0b013e31804a859b
更新日期:2007-06-01 00:00:00
abstract::All outcome studies of child and adolescent residential treatment and inpatient psychiatric hospitalization reported in the literature from 1975 to the present were examined. A set of statistical procedures was developed to integrate the findings of the 34 studies, which provided a weighted predictive value for 10 var...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199011000-00001
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:Daily living skills are a predictor of positive outcomes in individuals with autism spectrum disorder (ASD), yet little is known about trajectories of daily living skills in adults with ASD. This study investigated the impact of high school exit on participants' trajectories of daily living skills age equival...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2020.11.008
更新日期:2020-11-17 00:00:00
abstract:OBJECTIVE:To elucidate the effects of tricyclic antidepressants on sympathetic and vagal modulation of heart rate variability. METHOD:Seventy-five children and adolescents (mean age 10.5 years, SD 2.0) from therapeutic and regular schools underwent challenges of paced breathing and orthostatic postural change, while h...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199801000-00017
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To examine the validity of the Suicide Risk Screen (SRS) for identifying suicide-risk youths among potential high school dropouts. METHOD:Five hundred eighty-one potential dropouts, aged 14 to 20 years, participated in a 3-stage case identification protocol. A potential dropout pool was created in 7 schools;...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199912000-00011
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To examine the startle reflex as a possible vulnerability marker among offspring of parents with anxiety disorders and/or alcoholism. METHOD:The subjects were 66 male and female offspring (aged 10 to 17 years) of proband who participated in a family study of comorbidity of alcoholism and anxiety disorders. T...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199707000-00014
更新日期:1997-07-01 00:00:00