A secular increase in child and adolescent onset affective disorder.

Abstract:

:Both longitudinal and cross-sectional studies utilizing population and family study samples have found evidence for a secular increase in major affective disorders in adults. Applying techniques used in cross-sectional studies in adults to family study data of children and adolescents, the authors demonstrate evidence of a parallel secular increase for child and adolescent onset affective disorders. Normal and depressed prepubertal probands were identified. All full siblings were directly interviewed for lifetime episodes of affective disorder. Analysis of the siblings (probands not further analyzed in this article) by the Cox proportional hazards model demonstrates that the risk for affective disorder is higher in siblings born more recently.

authors

Ryan ND,Williamson DE,Iyengar S,Orvaschel H,Reich T,Dahl RE,Puig-Antich J

doi

10.1097/00004583-199207000-00004

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

600-5

issue

4

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(09)64073-9

journal_volume

31

pub_type

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