Cognitive-behavioral therapy for adolescent depression: a meta-analytic investigation of changes in effect-size estimates.

Abstract:

OBJECTIVE:To explicate differences between early and recent meta-analytic estimates of the effects of cognitive-behavioral therapy (CBT) for adolescent depression. METHOD:Meta-analytic procedures were used to investigate whether methodological characteristics moderated mean effect sizes among 11 randomized, controlled trials of CBT focusing on adolescents meeting diagnostic criteria for unipolar depression. RESULTS:Cumulative meta-analyses indicated that effects of CBT have decreased from large effects in early trials, and confidence intervals have become narrower. Effect sizes were significantly smaller among studies that used intent-to-treat analytic strategies, compared CBT to active treatments, were conducted in clinical settings, and featured greater methodological rigor based on CONSORT (Consolidated Standards of Reporting Trials) criteria. The mean posttreatment effect size of 0.53 was statistically significant. CONCLUSIONS:Differences in estimates of the efficacy of CBT for depressed adolescents may stem from methodological differences between early and more recent investigations. Overall, results support the effectiveness of CBT for the treatment of adolescent depression.

authors

Klein JB,Jacobs RH,Reinecke MA

doi

10.1097/chi.0b013e3180592aaa

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

1403-13

issue

11

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(09)62037-2

journal_volume

46

pub_type

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