Clomipramine in autism: preliminary evidence of efficacy.

Abstract:

:This report provides preliminary evidence for the efficacy of clomipramine in the treatment of young adults with autistic disorder. Four of five outpatients with autistic disorder showed significant improvement in social relatedness, obsessive compulsive symptoms, and aggressive and impulsive behavior with clomipramine treatment. These findings are consistent with previous evidence, suggesting that serotonin neurotransmission may be relevant to the treatment, and possibly the pathophysiology, of some symptoms of autistic disorder.

authors

McDougle CJ,Price LH,Volkmar FR,Goodman WK,Ward-O'Brien D,Nielsen J,Bregman J,Cohen DJ

doi

10.1097/00004583-199207000-00025

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

746-50

issue

4

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(09)64094-6

journal_volume

31

pub_type

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