Abstract:
OBJECTIVE:To test the hypothesis that methylphenidate reduces thresholds for reward in children with attention-deficit hyperactivity disorder (ADHD). METHOD:A double-blind crossover design was used in which 16 ADHD boys, aged 8 to 13 years, received methylphenidate on one testing occasion and placebo on another. On each occasion, subjects performed a task that required progressively greater numbers of button presses to earn a fixed monetary payoff. RESULTS:The "breaking point" above which the hyperactive child was unwilling to continue with the task was significantly higher during drug than placebo trials. CONCLUSIONS:The results support an assumption that underlies the reward system dysfunction hypothesis of ADHD, and they suggest that reward mechanisms may underlie the therapeutic effects of stimulants observed across a wide range of tasks and settings.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Wilkison PC,Kircher JC,McMahon WM,Sloane HNdoi
10.1097/00004583-199507000-00013subject
Has Abstractpub_date
1995-07-01 00:00:00pages
897-901issue
7eissn
0890-8567issn
1527-5418pii
S0890-8567(09)63600-5journal_volume
34pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:To describe the rationale, methodology, and sample characteristics of a dual-site treatment study (New York and Montreal) of children with attention-deficit/hyperactivity disorder (ADHD) conducted between 1990 and 1995. The hypotheses were that (1) methylphenidate combined with comprehensive multimodal psycho...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.chi.0000128798.91601.fe
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:To examine the association between physical abuse and selected psychosocial measures in a community-based probability sample of children and adolescents. METHOD:A sample of 9- through 17-year-olds (N = 665) and their caretakers in New York State and Puerto Rico were interviewed in the Methods for the Epidemi...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199701000-00026
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:We conducted a meta-analysis to examine the following: the time course of response to selective serotonin reuptake inhibitors (SSRIs) and clomipramine in pediatric obsessive-compulsive disorder (OCD); whether higher doses of SSRIs are associated with an improved response in pediatric OCD; differences in effic...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jaac.2016.07.768
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To examine the optimal Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) percent reduction cutoffs for predicting treatment response and clinical remission among children and adolescents with obsessive-compulsive disorder (OCD). METHOD:Youth with OCD (N = 109; range 7 to 19 years) received 14 sessio...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2010.04.005
更新日期:2010-07-01 00:00:00
abstract::Comorbidity, time to recovery, rate of chronicity, and probability of recurrence following recovery were studied in 51 children diagnosed with attention deficit disorder, conduct disorder, and oppositional defiant disorder. Thirty-three percent of the children had two of the above diagnoses, and one child had all thre...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199203000-00005
更新日期:1992-03-01 00:00:00
abstract:OBJECTIVE:To determine what clinical symptoms clinicians have been using to distinguish between Asperger's disorder (AsD) and autistic disorder (AD). METHOD:Parents of children and adolescents with high-functioning AD (n = 48) and AsD (n = 69) were given a structured interview based on DSM-III-R and ICD-10 diagnostic ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199611000-00022
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To examine whether first-episode psychosis patients with onset during adolescence (ages 15-18) differ significantly from those with young-adult onset (ages 19-30). METHOD:Consecutive patients presenting with first-episode psychosis (N = 242) were assessed for demographic and illness characteristics such as d...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.chi.0000164591.55942.ea
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:Child maltreatment is associated with dysregulation of stress-mediating systems and an increased risk of mental and physical health problems. Specifically, disruptions in hypothalamic-pituitary-adrenal (HPA) axis regulation have been reported in maltreated children. The current study investigates whether incr...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2014.08.006
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:This study assessed the relationship between the need for and use of mental health services among a nationally representative sample of children who were investigated by child welfare agencies after reported maltreatment. METHOD:Data were collected at study entry into the National Survey of Child and Adolesc...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.chi.0000127590.95585.65
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:Pediatric anxiety disorders can have a chronic course and are considered gateway disorders to adult psychopathology, but no consistent predictors of long-term outcome have been identified. A single latent symptom dimension that reflects features shared by all mental health disorders, the p factor, is thought ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2020.08.440
更新日期:2020-09-17 00:00:00
abstract:OBJECTIVE:To examine the individual and family characteristics of children and adolescents with high levels of hopelessness. METHOD:One hundred inpatient youngsters participated in the study. Several measures, including the Hopelessness Scale for Children, Problem Behavior Scale of the Scales of Independent Behavior, ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/S0890-8567(09)66575-8
更新日期:1997-11-01 00:00:00
abstract::The prevalence of psychiatric disorders, such as major depression and anxiety, is higher in sexual minority individuals (eg, those who identify as gay, lesbian, or bisexual or are unsure of their orientation) than heterosexual individuals.1 Eating disorders and alcohol use also are more common in sexual minority group...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 评论,社论
doi:10.1016/j.jaac.2018.11.006
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To examine whether childhood attention-deficit/hyperactivity disorder (ADHD) predicts homelessness in adulthood, and whether the persistence of childhood ADHD through adolescence influences the likelihood of homelessness. METHOD:A 33-year prospective, controlled, follow-up was performed of clinic-referred, 6...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2016.07.772
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:This study examined predictors of strategies used to cope with pain in children with sickle cell disease and their mothers. METHOD:Disease severity, socioeconomic status, child adjustment and adaptive behavior, maternal psychopathology, and family functioning were examined in 55 mother-child dyads to determi...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199411000-00005
更新日期:1994-11-01 00:00:00
abstract::Thirty 6- to 9-year-old boys were rated by their mothers and teachers as being pervasively hyperactive, situationally hyperactive, or not hyperactive at home or school. Maternal characteristics and perceptions of their children's behavior problems were collected. Children's global and molecular social skills were also...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199007000-00008
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:To assess whether being bullied between 7 and 10 years of age is directly associated with self-harm in late adolescence when controlling for previous exposure to an adverse family environment (domestic violence, maladaptive parenting); concurrent internalizing and externalizing behavior; and subsequent psycho...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2013.03.012
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Bulimia nervosa (BN) is characterized by excessive attention to self and specifically to body shape and weight, but the ventral attention (VAN) and default mode (DMN) networks that support attentional and self-referential processes are understudied in BN. This study assessed whether altered functional connect...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2018.09.433
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:Recent cross-sectional studies of adolescents have noted an association between the personality traits of perfectionism and self-criticism and suicidal ideation. The present study was undertaken to examine the relationship between personality dimensions and the outcome of treatment of adolescents hospitalized...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.CHI.0000046847.56865.B0
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To assess the effects of desipramine (DMI) on autonomic control of the heart. METHODS:Blood pressure, RR interval (the time between successive heart beats), and RR interval variability, a noninvasive measure of autonomic control of the heart, were assessed in 13 subjects younger than 30 years old. RESULTS:D...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199402000-00006
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:To elucidate the effects of tricyclic antidepressants on sympathetic and vagal modulation of heart rate variability. METHOD:Seventy-five children and adolescents (mean age 10.5 years, SD 2.0) from therapeutic and regular schools underwent challenges of paced breathing and orthostatic postural change, while h...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199801000-00017
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:The present investigation tested the hypothesis that low resting salivary cortisol concentration in preadolescent boys would be associated with aggressive behavior later in adolescence. Second, it tested whether personality traits would mediate this relation. METHOD:Resting salivary cortisol concentrations f...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/01.CHI.0000070246.24125.6D
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To examine the association between both parental and offspring depression and the general medical problems of a sample of offspring at high and low risk for depression. METHOD:Offspring (n = 222) from families with either depressed or nondepressed parents were followed up for a period of 10 years. Data colle...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199806000-00010
更新日期:1998-06-01 00:00:00
abstract::All outcome studies of child and adolescent residential treatment and inpatient psychiatric hospitalization reported in the literature from 1975 to the present were examined. A set of statistical procedures was developed to integrate the findings of the 34 studies, which provided a weighted predictive value for 10 var...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199011000-00001
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVES:The primary objective of the study was to assess whether the Availability, Responsiveness and Continuity (ARC) organizational intervention improved youth outcomes in community based mental health programs. The second objective was to assess whether programs with more improved organizational social contexts f...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jaac.2013.02.005
更新日期:2013-05-01 00:00:00
abstract::Although mental health and correctional programs for juveniles house similar populations, their approaches to behavioral management can be quite different. This difference is evident in the use of isolation and restraint. Both of these interventions are effective behavioral management tools but are subject to abuse if...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199003000-00014
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:The association between depression and educational attainment in young people is unclear. This systematic review and meta-analysis examines the longitudinal association between depression and subsequent attainment, and its potential effect modifiers and mediators. METHOD:We searched Embase, PsycINFO, PubMed,...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2020.10.008
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:A reliable diagnosis of autism can be made as early as 24 months, yet in many children diagnoses are made much later. A delay in diagnosis translates into a missed opportunity to provide early intervention services and to improve outcomes. The aim of the current study was to review the literature on early de...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2013.11.002
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of Safe Thinking and Affect Regulation (STAR), a 14-session HIV-prevention program for adolescents at alternative/therapeutic schools. Because these youth frequently have difficulties with emotions and cognitions, it was designed to improve sexuality-specific affect management an...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaac.2011.06.018
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:Family interventions have been found to be effective in pediatric bipolar disorder (BD). This study examined the moderating effects of parental expressed emotion (EE) on the 2-year symptomatic outcomes of adolescent BD patients assigned to family-focused therapy for adolescents (FFT-A) or a brief psychoeducat...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/CHI.0b013e3181a0ab9d
更新日期:2009-06-01 00:00:00
abstract::Bullying is a global phenomenon with significant mental health consequences. Although bullying prevention programs have garnered attention over the last several years, the results of these programs have been mixed, at best. As Koyanagi et al.1 highlight in this issue of the Journal, the consequences of bullying can be...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 评论,社论
doi:10.1016/j.jaac.2019.04.007
更新日期:2019-09-01 00:00:00