Abstract：
:We examined morphological characteristics of the carotid body of spontaneously hypertensive rats (SHR), those of age-matched normotensive Wistar rats (NWR), and age-matched genetically comparable Wistar Kyoto rats (WKY). We examined the distribution and abundance of four different regulatory neuropeptides: substance P (SP), calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP), and neuropeptide Y (NPY) in the carotid bodies of these three strains of rats. The carotid bodies of SHR were larger than those of NWR and WKY. The values of the long axis of the carotid bodies of SHR were significantly larger (1.3 times) than those of NWR and WKY. In the carotid bodies of SHR, the percentage of relatively large vessels was similar to that of the carotid bodies of WKY, although the carotid bodies themselves were significantly larger than in WKY. The density of VIP varicose fibers in the carotid bodies of SHR was lower than in the carotid bodies of WKY, although the density of SP, CGRP and NPY fibers was similar to that of the carotid bodies of NWR and WKY. These findings suggested that VIP was unrelated to enlargement of the carotid body of SHR, but it might modify the sensitivity of chemoreceptors in the carotid body.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Takahashi M,Matsuda H,Hayashida Y,Yamamoto Y,Tsukuda M,Kusakabe Tdoi
10.14670/HH-26.369subject
Has Abstractpub_date
2011-03-01 00:00:00pages
369-75issue
3eissn
0213-3911issn
1699-5848journal_volume
26pub_type
杂志文章abstract：:Treatment of neurodegenerative diseases by classical pharmacotherapy is restricted by blood-brain barrier which prevents access to the brain of potentially therapeutic molecules. Recent progress in the knowledge of pathophysiological molecular processes, and in the development of molecular biotechnology have opened th...
journal_title：Histology and histopathology
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abstract：:There is scarce information on the possible effects of chronic exposure to mercury on skeletal muscle. Dental personnel are frequently exposed to inhalation of metallic mercury vapours. The skeletal muscle of five technicians and one dentist (females, age 36-55) was studied. All of them presented symptoms of chronic m...
journal_title：Histology and histopathology
pub_type： 杂志文章
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journal_title：Histology and histopathology
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doi：
更新日期：1997-10-01 00:00:00
abstract：:Oligodendrocytes are the myelinating cells of the central nervous system. Since many studies of demyelinating diseases focus their research on this cell type, there is growing interest for obtaining reliable markers that can specifically recognize oligodendroglia. Established markers are the myelin-associated neurite ...
journal_title：Histology and histopathology
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journal_title：Histology and histopathology
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doi：
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
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journal_title：Histology and histopathology
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journal_title：Histology and histopathology
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doi：
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journal_title：Histology and histopathology
pub_type： 杂志文章
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更新日期：2012-06-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-19.701
更新日期：2004-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
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更新日期：2001-01-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
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更新日期：2012-09-01 00:00:00
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journal_title：Histology and histopathology
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更新日期：2017-12-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-11-925
更新日期：2018-03-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1993-04-01 00:00:00
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更新日期：2020-09-11 00:00:00
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journal_title：Histology and histopathology
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doi：
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journal_title：Histology and histopathology
pub_type： 杂志文章
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更新日期：1999-10-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
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更新日期：2009-09-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
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更新日期：2003-07-01 00:00:00
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journal_title：Histology and histopathology
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-25.45
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abstract：:Current data on the influence of neuropeptides on the growth, structure and function of cells comprising the hypothalamo-pituitary-adrenal axis were presented and discussed. The action of vasopressin, oxytocin, neurotensin, bombesin, neuropeptide Y, substance P and VIP have been evaluated. The hypothesis has been intr...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
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