Abstract：
OBJECTIVES:To determine the relationship between BiliChek TcB (Respironics, Marietta GA) and Doumas reference serum or plasma total bilirubin (TSB). DESIGN AND METHODS:Pooled samples with values assigned by the Doumas reference method were used to establish the relationship between a local laboratory and reference Doumas TSB. We then established the relationship between TcB and TSB in the 3 months before and after reassignment of calibrator setpoints undertaken to match the local laboratory to Doumas reference bilirubin values. RESULTS:Before calibrator setpoint reassignment TSB as measured in our laboratory overestimated Doumas reference bilirubin. After calibrator adjustment laboratory TSB was within 1.7-6.8 micromol/L (0.1-0.4 mg/dL) of Doumas reference values. Mean bias between BiliChek TcB and TSB was 42.8+/-22.2 micromol/L (2.5+/-1.3mg/dL) (n=94) before and 49.6+/-22.2 micromol/L (2.9+/-1.3mg/dL) (n=115) after calibration adjustment. CONCLUSIONS:BiliChek TcB significantly overestimates TSB as measured by the Doumas reference method.
journal_name
Clin Biochemjournal_title
Clinical biochemistryauthors
Karon BS,Wickremasinghe AC,Lo SF,Saenger AK,Cook WJdoi
10.1016/j.clinbiochem.2010.04.065subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1009-12issue
12eissn
0009-9120issn
1873-2933pii
S0009-9120(10)00198-0journal_volume
43pub_type
杂志文章abstract：OBJECTIVES:The aim was to study the influence of sampling time, food intake and sleep on tests used to screen for and monitor conditions of iron deficiency and overload. DESIGN AND METHODS:The 24 h variations of iron, transferrin, transferrin saturation (TS) and ferritin were studied in seven healthy individuals durin...
journal_title：Clinical biochemistry
pub_type： 临床试验,杂志文章
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更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:To evaluate the results of oxygen consumption measurement in lymphocytes for the diagnosis and treatment monitoring of pediatric patients with oxidative phosphorylation diseases. DESIGN AND METHODS:Twenty-four children with an oxidative phosphorylation disease were studied. Results were compared with those ...
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doi：10.1016/s0009-9120(00)00062-x
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Gliomas are tumors of the central nervous system derived from glial cells. They show cellular heterogeneity and lack specific diagnostic markers. Although a possible role for the eicosanoid cascade has been suggested in glioma tumorigenesis, the relationship between enzymes and receptors implicated in arachi...
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abstract：BACKGROUND:A determination of serum Transthyretin (TTR, Prealbumin) level is an objective method of assessing protein catabolic loss of severely ill patients and numerous studies have shown that TTR levels correlate with patient outcomes of non-critically ill patients. We evaluated whether TTR level correlates with the...
journal_title：Clinical biochemistry
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doi：10.1016/j.clinbiochem.2008.06.016
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Colorectal cancer (CRC) is one of the most common cancers worldwide, and emerging lines of evidence have implicated circular RNAs (circRNAs), a novel class of endogenous noncoding RNAs, in CRC development. However, whether plasma circRNAs might be novel diagnostic biomarkers for CRC remains unclear. METHODS...
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2016.02.003
更新日期：2016-09-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
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doi：10.1016/j.clinbiochem.2008.11.015
更新日期：2009-04-01 00:00:00
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更新日期：1996-10-01 00:00:00
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doi：10.1016/j.clinbiochem.2015.08.012
更新日期：2016-01-01 00:00:00
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doi：10.1016/j.clinbiochem.2018.04.016
更新日期：2018-06-01 00:00:00
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doi：10.1016/j.clinbiochem.2015.06.016
更新日期：2015-11-01 00:00:00
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journal_title：Clinical biochemistry
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更新日期：2013-05-01 00:00:00
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更新日期：2014-04-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
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更新日期：2005-05-01 00:00:00
abstract：:Retrospective analysis of DNA from paraffin-embedded fixed bone marrow biopsy specimens is possible if preceded by amplification of the DNA sequences of interest by the polymerase chain reaction (PCR). These fixed specimens yield degraded DNA that may not be suitable for direct analysis by conventional digestion and h...
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pub_type： 杂志文章
doi：10.1016/0009-9120(92)80051-h
更新日期：1992-04-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
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更新日期：1989-08-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章,评审
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更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:MicroRNA-331 (miR-331) has shown regulatory activity against several genes whose expression has been claimed to be deregulated in breast tumors, including that of epidermal growth factor receptor 2 (HER2). Herein, the clinical value of miR-331 expression was investigated by analyzing its levels in breast beni...
journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2018.07.008
更新日期：2018-09-01 00:00:00
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journal_title：Clinical biochemistry
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doi：10.1016/j.clinbiochem.2015.01.015
更新日期：2015-05-01 00:00:00
