Prospective memory functioning in mild cognitive impairment.

Abstract:

OBJECTIVE:The present study aimed to investigate prospective memory (PM) in persons with mild cognitive impairment (MCI). METHOD:Twenty individuals with MCI (10 with an amnestic profile and 10 with a dysexecutive profile of cognitive impairment) and 20 control subjects (CS) were recruited. In the PM tasks, subjects had to execute three actions after 20 min had elapsed (time-based condition) or after a timer rang (event-based condition). Separate scores were computed for correct recall of the intention to perform the actions (prospective component) and for correct execution of the actions (retrospective component). RESULTS:Although individuals with MCI were less accurate than CS in both prospective (Cohen's d ranged from 1.04 to 2.23) and retrospective (Cohen's d ranged from 0.81 to 1.06) components of the experimental task, they were significantly more impaired in the former than the latter component (Cohen's d = 0.42). Moreover, the deficit in the prospective component of the time-based task was particularly evident in MCI participants presenting with a dysexecutive impairment in respect to amnestic MCI individuals (Cohen's d = 0.99). CONCLUSIONS:Results of the present study show that the ability of subjects with MCI to comply effectively with a planned delayed intention is impaired and suggest that dysexecutive disorders are likely responsible for this deficit.

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

Costa A,Perri R,Serra L,Barban F,Gatto I,Zabberoni S,Caltagirone C,Carlesimo GA

doi

10.1037/a0018015

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

327-35

issue

3

eissn

0894-4105

issn

1931-1559

pii

2010-07896-005

journal_volume

24

pub_type

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