The relationship between working memory capacity and broad measures of cognitive ability in healthy adults and people with schizophrenia.

Abstract:

OBJECTIVE:Working memory (WM) capacity, typically measured with cognitively complex span tasks, is correlated with higher order cognitive abilities in healthy adults. The goals of this study were to determine whether a more focused measure of visual WM storage capacity would show similar higher order ability correlations in healthy adults and in people with schizophrenia (PSZ), thereby demonstrating the importance of simple storage capacity; determine whether the illness alters the pattern of correlations across cognitive domains; and evaluate whether between-groups differences in WM capacity could account for the generalized cognitive impairment in PSZ. METHOD:Ninety-nine PSZ and 77 healthy controls (HCs) completed a visual WM change-localization task, the Wechsler Abbreviated Scale of Intelligence (WASI), and the MATRICS Consensus Cognitive Battery (MCCB). RESULTS:PSZ performed more poorly than HCs on all cognitive measures. The between-groups effect size for WM capacity was large (d = 1.11). WM robustly correlated with WASI and MCCB performance, with no significant differences in the magnitude or pattern of correlations across groups. When the groups were pooled, WM capacity correlated at r = .68 with MCCB composite score and at r = .56 with WASI estimated Full Scale IQ. WM capacity accounted for approximately 40% of the between-groups variance across the WASI and MCCB. CONCLUSIONS:A simple measure of WM storage capacity is robustly associated with the higher order cognitive abilities assessed by the WASI and MCCB in HCs and PSZ. WM capacity reduction may be a critical determinant of the general cognitive impairment in PSZ.

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

Johnson MK,McMahon RP,Robinson BM,Harvey AN,Hahn B,Leonard CJ,Luck SJ,Gold JM

doi

10.1037/a0032060

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

220-9

issue

2

eissn

0894-4105

issn

1931-1559

pii

2013-09661-009

journal_volume

27

pub_type

杂志文章
  • Hemispheric interactions during a face--word Stroop-analog task.

    abstract::A Stroop-analog task with faces and words was developed to investigate intrahemispheric and interhemispheric Stroop effects (SEs). Lateralized faces and words were used in an attempt to invoke right- and left-hemispheric specialization, respectively. A prototypical male face, female face, and baby face and the corresp...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037//0894-4105.14.4.579

    authors: Kavcic V,Clarke JM

    更新日期:2000-10-01 00:00:00

  • Normative data for verbal fluency in healthy Latin American adults: Letter M, and fruits and occupations categories.

    abstract:OBJECTIVE:To generate normative data for the verbal fluency tests (VFT-letter M, fruits, and occupations categories) in Spanish-speaking adult populations, with country-specific adjustments for age, education, and sex when appropriate. METHOD:The sample consisted of 3,977 healthy adults from 11 countries in Latin Amer...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000518

    authors: Rivera D,Olabarrieta-Landa L,Van der Elst W,Gonzalez I,Rodríguez-Agudelo Y,Aguayo Arelis A,Rodriguez-Irizarry W,García de la Cadena C,Arango-Lasprilla JC

    更新日期:2019-03-01 00:00:00

  • Longitudinal analysis of phonemic clustering and switching during word-list generation in Huntington's disease.

    abstract::Two characteristics of word-list generation performance are forming clusters (i.e., contiguous words from the same subcategory) and switching among them. Patients with frontal lobe pathology show reduced switching on letter-cued word generation tasks, and clustering has been associated with temporal lobe functioning. ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037//0894-4105.13.4.525

    authors: Rich JB,Troyer AK,Bylsma FW,Brandt J

    更新日期:1999-10-01 00:00:00

  • Advances in neurocognitive rehabilitation research from 1992 to 2017: The ascension of neural plasticity.

    abstract:OBJECTIVE:The last 25 years have seen profound changes in neurocognitive rehabilitation that continue to motivate its evolution. Although the concept of nervous system plasticity was discussed by William James (1890), the foundation for experience-based plasticity had not reached the critical empirical mass to seriousl...

    journal_title:Neuropsychology

    pub_type: 杂志文章,评审

    doi:10.1037/neu0000396

    authors: Crosson B,Hampstead BM,Krishnamurthy LC,Krishnamurthy V,McGregor KM,Nocera JR,Roberts S,Rodriguez AD,Tran SM

    更新日期:2017-11-01 00:00:00

  • Variability in performance: identifying early signs of future cognitive impairment.

    abstract:OBJECTIVE:The current study examined whether year-to-year variability in cognitive performance differ between individuals cognitively unimpaired and individuals who subsequently develop dementia. METHOD:Analyses included a case-control sample of Baltimore Longitudinal Study of Aging (BLSA; mean [M] age = 69.90, standa...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0028686

    authors: Gamaldo AA,An Y,Allaire JC,Kitner-Triolo MH,Zonderman AB

    更新日期:2012-07-01 00:00:00

  • Sustained attention in children with two etiologies of early hydrocephalus.

    abstract::Several studies have shown that children with spina bifida meningomyelocele (SBM) and hydrocephalus have attention problems on parent ratings and difficulties in stimulus orienting associated with a posterior brain attention system. Less is known about response control and inhibition associated with an anterior brain ...

    journal_title:Neuropsychology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1037/a0013373

    authors: Swartwout MD,Cirino PT,Hampson AW,Fletcher JM,Brandt ME,Dennis M

    更新日期:2008-11-01 00:00:00

  • Executive functions and the contribution of short-term memory span in children with specific language impairment.

    abstract:OBJECTIVE:An increasing number of results show that specific language impairment (SLI) is often associated with impairments in executive functions (EF), but the nature, extent, and generality of these deficits is yet unclear. The aim of the paper is to present results from verbal and nonverbal tasks examining EF in chi...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000232

    authors: Lukács Á,Ladányi E,Fazekas K,Kemény F

    更新日期:2016-03-01 00:00:00

  • Decussation as an axial twist: A comment on Kinsbourne (2013).

    abstract::One of the great mysteries of the brain, which has puzzled all-time students of brain form and function, is the contralateral organization of the forebrain and the crossings of its major afferent and efferent connections. As a novel explanation, two recent studies have proposed that the rostral part of the head, inclu...

    journal_title:Neuropsychology

    pub_type: 评论,杂志文章

    doi:10.1037/neu0000163

    authors: de Lussanet MH,Osse JW

    更新日期:2015-09-01 00:00:00

  • Depressive symptoms precede cognitive impairment in de novo Parkinson's disease patients: Analysis of the PPMI cohort.

    abstract:INTRODUCTION:Nonmotor symptoms, including depression, anxiety, apathy, and cognitive dysfunction, are common in Parkinson's disease (PD). Although a link between mood symptoms and cognitive impairment in PD has been theorized vis-à-vis striatal dopamine depletion, studies have been inconsistent regarding the relationsh...

    journal_title:Neuropsychology

    pub_type: 杂志文章,多中心研究

    doi:10.1037/neu0000583

    authors: Jones JD,Kurniadi NE,Kuhn TP,Szymkowicz SM,Bunch J,Rahmani E

    更新日期:2019-11-01 00:00:00

  • Memory consolidation in aging and MCI after 1 week.

    abstract:OBJECTIVE:To assess consolidation in amnestic mild cognitive impairment (aMCI), controlling for differences in initial learning and using a protracted delay period for recall. METHOD:15 individuals with aMCI were compared with 15 healthy older adult controls on a story learning task. Subjects were trained to criteria ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000013

    authors: Walsh CM,Wilkins S,Bettcher BM,Butler CR,Miller BL,Kramer JH

    更新日期:2014-03-01 00:00:00

  • Alzheimer disease biomarkers, attentional control, and semantic memory retrieval: Synergistic and mediational effects of biomarkers on a sensitive cognitive measure in non-demented older adults.

    abstract:OBJECTIVE:Past studies have shown that measures of attentional control and semantic memory are sensitive markers of Alzheimer's disease (AD). The effects of established biomarkers of AD (cerebrospinal fluid tau and amyloid-beta42, positron emission tomography Pittsburgh compound-B, and apolipoprotein E [APOE] genotype)...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000133

    authors: Aschenbrenner AJ,Balota DA,Tse CS,Fagan AM,Holtzman DM,Benzinger TL,Morris JC

    更新日期:2015-05-01 00:00:00

  • No category specificity in Alzheimer's disease: a normal aging effect.

    abstract::The authors examined category effects on tasks of picture naming, naming to definition, and word-picture matching in 38 patients with Alzheimer's disease (AD) and 30 elderly controls. Each task was matched across category on all "nuisance" variables known to differ across domains. Standard analyses revealed significan...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.22.4.485

    authors: Moreno-Martínez FJ,Laws KR

    更新日期:2008-07-01 00:00:00

  • Are visual cues helpful for virtual spatial navigation and spatial memory in patients with mild cognitive impairment or Alzheimer's disease?

    abstract:OBJECTIVE:To evaluate whether visual cues are helpful for virtual spatial navigation and memory in Alzheimer's disease (AD) and patients with mild cognitive impairment (MCI). METHOD:20 patients with AD, 18 patients with MCI and 20 age-matched healthy controls (HC) were included. Participants had to actively reproduce ...

    journal_title:Neuropsychology

    pub_type: 杂志文章,随机对照试验

    doi:10.1037/neu0000435

    authors: Cogné M,Auriacombe S,Vasa L,Tison F,Klinger E,Sauzéon H,Joseph PA,N Kaoua B

    更新日期:2018-05-01 00:00:00

  • Gray matter integrity within regions of the dorsolateral prefrontal cortical-subcortical network predicts executive function and fine motor dexterity in spina bifida.

    abstract:OBJECTIVES:This study examined microstructural properties of cortical and subcortical gray matter components of the dorsolateral prefrontal (DLPFC) cortical-subcortical circuit in relation to parent-rated executive function and fine motor dexterity performance in youth with spina bifida myelomeningocele (SBM). Aberrant...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000266

    authors: Ware AL,Kulesz PA,Williams VJ,Juranek J,Cirino PT,Fletcher JM

    更新日期:2016-05-01 00:00:00

  • Examining frontotemporal connectivity and rTMS in healthy controls: implications for auditory hallucinations in schizophrenia.

    abstract:OBJECTIVE:Repetitive transcranial magnetic stimulation (rTMS) has been shown to have clinically beneficial effects in altering the perception of auditory hallucinations (AH) in patients with schizophrenia. However, the mode of action is not clear. Recent neuroimaging findings indicate that rTMS has the potential to ind...

    journal_title:Neuropsychology

    pub_type: 杂志文章,随机对照试验

    doi:10.1037/a0026603

    authors: Gromann PM,Tracy DK,Giampietro V,Brammer MJ,Krabbendam L,Shergill SS

    更新日期:2012-01-01 00:00:00

  • Multimodal cuing of autobiographical memory in semantic dementia.

    abstract:OBJECTIVE:Individuals with semantic dementia (SD) have impaired autobiographical memory (AM), but the extent of the impairment has been controversial. According to one report (Westmacott, Leach, Freedman, & Moscovitch, 2001), patient performance was better when visual cues were used instead of verbal cues; however, the...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0021005

    authors: Greenberg DL,Ogar JM,Viskontas IV,Gorno Tempini ML,Miller B,Knowlton BJ

    更新日期:2011-01-01 00:00:00

  • Characterizing multiple memory deficits and their relation to everyday functioning in individuals with mild cognitive impairment.

    abstract::The authors evaluated multiple memory processes and explored their contributions to everyday functional limitations in persons with mild cognitive impairment (MCI). Participants included individuals with amnestic MCI, nonamnestic MCI, and healthy older adults. As expected, the amnestic MCI group performed more poorly ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0014186

    authors: Schmitter-Edgecombe M,Woo E,Greeley DR

    更新日期:2009-03-01 00:00:00

  • Recreational use of cocaine eliminates inhibition of return.

    abstract::Chronic and recreational use of cocaine has been shown to impair inhibitory output control (response inhibition) but whether input control is also affected is an open question. For the first time, this study compared the ability to perform a cued target-discrimination task that measured inhibition of return (IOR), a r...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0013821

    authors: Colzato LS,Hommel B

    更新日期:2009-01-01 00:00:00

  • Pediatric traumatic brain injury affects multisensory integration.

    abstract:OBJECTIVE:To investigate the impact of pediatric traumatic brain injury (TBI) on multisensory integration in relation to general neurocognitive functioning. METHOD:Children with a hospital admission for TBI aged between 6 and 13 years (n = 94) were compared with children with trauma control (TC) injuries (n = 39), whi...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000302

    authors: Königs M,Weeda WD,van Heurn LW,Vermeulen RJ,Goslings JC,Luitse JS,Poll-The BT,Beelen A,van der Wees M,Kemps RJ,Catsman-Berrevoets CE,Oosterlaan J

    更新日期:2017-02-01 00:00:00

  • Morphological structure and hemispheric functioning: the contribution of the right hemisphere to reading in different languages.

    abstract::This study examined the relationship between morphological structure of languages and performance asymmetries of native speakers in lateralized tasks. In 2 experiments, native speakers of English (concatenative morphology stem plus affix) and of Hebrew and Arabic (nonconcatenative root plus word-form morphology) were ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.21.4.470

    authors: Eviatar Z,Ibrahim R

    更新日期:2007-07-01 00:00:00

  • Attention and memory dysfunction in posttraumatic stress disorder.

    abstract::Attention and memory performances were studied in Persian Gulf War veterans with and without posttraumatic stress disorder (PTSD) diagnoses. Veterans diagnosed with PTSD showed relative performance deficiencies on tasks of sustained attention, mental manipulation, initial acquisition of information, and retroactive in...

    journal_title:Neuropsychology

    pub_type: 临床试验,杂志文章

    doi:10.1037//0894-4105.12.1.125

    authors: Vasterling JJ,Brailey K,Constans JI,Sutker PB

    更新日期:1998-01-01 00:00:00

  • Cognition and daily life functioning among persons with serious mental illness: A cluster analytic examination of heterogeneity on the Test of Grocery Shopping Skills.

    abstract:OBJECTIVE:To characterize variability in daily life functioning among individuals with serious mental illness based on a naturalistic performance measure of grocery shopping and standard neuropsychological tasks using cluster analytic methods. METHODS:A naturalistic performance measure, the Test of Grocery Shopping Sk...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000700

    authors: Harris M,Blanco EA,Rempfer M

    更新日期:2021-01-01 00:00:00

  • Phonological blocking during picture naming in dementia of the Alzheimer type.

    abstract::Individuals with dementia of the Alzheimer type (DAT; n = 53, ages 55-91), healthy older adults (n = 75, ages 59-91), and younger adults (n = 24, ages 18-24) performed a word-primed picture-naming task. Word primes were neutral (ready), semantically or phonologically related, or unrelated to the correct picture name. ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.18.3.526

    authors: Faust ME,Balota DA,Multhaup KS

    更新日期:2004-07-01 00:00:00

  • Preliminary evidence for differential trajectories of recovery for cognitive flexibility following sports-related concussion.

    abstract:OBJECTIVE:A critical barrier to the understanding of disruptions to cognitive flexibility following sports-related concussion is the use of assessments that conflate shifts of visuospatial attention and contextual rules. Because these dissociable forms of cognitive flexibility are subserved by distinct neural networks,...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000475

    authors: McGowan AL,Bretzin AC,Savage JL,Petit KM,Parks AC,Covassin T,Pontifex MB

    更新日期:2018-07-01 00:00:00

  • What do eye movements tell us about the visual perception of individuals with congenital prosopagnosia?

    abstract:OBJECTIVE:The lack of inversion effect for face recognition in congenital prosopagnosia (CP) is consistent with the hypothesis of a failure in holistic processing. However, although CPs' abnormal gaze behavior for upright faces has already been demonstrated, neither their scanning strategy for inverted faces, nor the p...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000362

    authors: Malaspina M,Albonico A,Toneatto C,Daini R

    更新日期:2017-07-01 00:00:00

  • Superior episodic memory is associated with interhemispheric processing.

    abstract::The dependence of episodic memories on interhemispheric processing was tested. In Experiment 1, positive familial sinistrality (FS+; e.g., presence of left-handed relatives) was associated with superior episodic memory and inferior implicit memory in comparison with negative familial sinistrality (i.e., FS-). This ref...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037//0894-4105.15.4.607

    authors: Christman SD,Propper RE

    更新日期:2001-10-01 00:00:00

  • Intraindividual variability in neuropsychological performance predicts cognitive decline and death in HIV.

    abstract:OBJECTIVE:HIV-associated neurocognitive disorder (HAND) occurs in a significant percentage of HIV-infected (HIV+) adults. Increased intraindividual variability (IIV) in cognitive function may be an early marker of emerging neurocognitive disorder, which suggests that IIV may be a sensitive measure of neurologic comprom...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000482

    authors: Anderson AE,Jones JD,Thaler NS,Kuhn TP,Singer EJ,Hinkin CH

    更新日期:2018-11-01 00:00:00

  • Difference rather than delay in development of elementary visuomotor processes in children born preterm without cerebral palsy: a quasi-longitudinal study.

    abstract::Follow-up studies of preterm children without serious neonatal medical complications have consistently found poor visuomotor and visuospatial skills. In the first round of current follow-up study, we found a deficit in elementary visuomotor processes in preterm children without Cerebral Palsy (CP). To determine whethe...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0016804

    authors: Van Braeckel K,Butcher PR,Geuze RH,van Duijn MA,Bos AF,Bouma A

    更新日期:2010-01-01 00:00:00

  • Abnormal error-related antisaccade activation in premanifest and early manifest Huntington disease.

    abstract:OBJECTIVE:Individuals with the trinucleotide CAG expansion (CAG+) that causes Huntington's disease (HD) have impaired performance on antisaccade (AS) tasks that require directing gaze in the mirror opposite direction of visual targets. This study aimed to identify the neural substrates underlying altered antisaccadic p...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0021873

    authors: Rupp J,Dzemidzic M,Blekher T,Bragulat V,West J,Jackson J,Hui S,Wojcieszek J,Saykin AJ,Kareken D,Foroud T

    更新日期:2011-05-01 00:00:00

  • Delay and reward choice in ADHD: an experimental test of the role of delay aversion.

    abstract::Children with attention deficit/hyperactivity disorder (ADHD) choose smaller sooner (SS) over larger later (LL) rewards more than controls. Here we assess the contributions of impulsive drive for immediate rewards (IDIR) and delay aversion (DAv) to this pattern. We also explore the characteristics of, and the degree o...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0014914

    authors: Marco R,Miranda A,Schlotz W,Melia A,Mulligan A,Müller U,Andreou P,Butler L,Christiansen H,Gabriels I,Medad S,Albrecht B,Uebel H,Asherson P,Banaschewski T,Gill M,Kuntsi J,Mulas F,Oades R,Roeyers H,Steinhausen HC,

    更新日期:2009-05-01 00:00:00