Visual selective attention in Parkinson's disease: dissociation of exogenous and endogenous inhibition.

Abstract:

:Impairment in the inhibitory mechanism of visual selective attention in patients with Parkinson's disease (PD) is controversial. The present study sought to understand disparate findings in a manner analogous to the relative preservation of exogenously evoked movement and impairment of endogenously evoked movement. The authors examined inhibition of return (i.e., exogenously evoked inhibition; IOR) and negative priming (i.e., endogenously evoked inhibition; NP) in a group of 14 patients with PD and 14 healthy controls (HC). Unlike the HC, who demonstrated significant inhibition in both tasks, the group with PD demonstrated intact inhibition only in the IOR task. Dopamine replacement therapy did not affect performance. The findings are discussed within the context of a model that differentiates the essential involvement of the basal ganglia for endogenously evoked spatial inhibition.

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

Grande LJ,Crosson B,Heilman KM,Bauer RM,Kilduff P,McGlinchey RE

doi

10.1037/0894-4105.20.3.370

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

370-82

issue

3

eissn

0894-4105

issn

1931-1559

pii

2006-06643-012

journal_volume

20

pub_type

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