Abstract：
:This report of a pilot study examines 29 pairs of twins from a population-based registry on whom four domains of schizotypy have been measured: personal interview using the Structured Interview for Schizotypy, self-report questionnaire formed from eight published self-report scales, attentional battery of eight individual tests, and root mean square error on smooth pursuit eye tracking. Analyzing the twins as individuals revealed two independent dimensions of clinically rated schizotypy (positive symptom schizotypy and negative symptom schizotypy) and two independent dimensions of self-rated schizotypy (positive trait schizotypy and trait anhedonia). Positive symptom schizotypy was highly correlated with positive trait schizotypy, but not with attentional dysfunction or eye-tracking error. By contrast, negative symptom schizotypy was significantly related to trait anhedonia, attentional dysfunction, and eye-tracking error. Correlations in monozygotic and dizygotic twins suggested that genetic factors were important in all four domains of schizotypy. Except for eye-tracking error, the results are more consistent with a dimensional than a "disease" model of schizotypy. Replication of these results with a larger group of subjects is needed.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Kendler KS,Ochs AL,Gorman AM,Hewitt JK,Ross DE,Mirsky AFdoi
10.1016/0165-1781(91)90114-5subject
Has Abstractpub_date
1991-01-01 00:00:00pages
19-36issue
1eissn
0165-1781issn
1872-7123pii
0165-1781(91)90114-5journal_volume
36pub_type
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