Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family.

Abstract:

:To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Yoo HJ,Woo RS,Cho SC,Kim BN,Kim JW,Shin MS,Park TW,Son JW,Chung US,Park S,Park M,Kim SA

doi

10.1016/j.psychres.2015.03.015

subject

Has Abstract

pub_date

2015-06-30 00:00:00

pages

366-8

issue

2-3

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(15)00139-0

journal_volume

227

pub_type

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