Abstract:
:To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Yoo HJ,Woo RS,Cho SC,Kim BN,Kim JW,Shin MS,Park TW,Son JW,Chung US,Park S,Park M,Kim SAdoi
10.1016/j.psychres.2015.03.015subject
Has Abstractpub_date
2015-06-30 00:00:00pages
366-8issue
2-3eissn
0165-1781issn
1872-7123pii
S0165-1781(15)00139-0journal_volume
227pub_type
杂志文章abstract::Both the [3H]imipramine and [3H]paroxetine binding sites and the 5-HT2A receptor were simultaneously determined in frontal cortex, cingulate cortex, hippocampus and amygdala from 17 control subjects and 17 depressed suicide victims. A significant decrease in the maximum binding (Bmax) of [3H]imipramine was observed in...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(98)00015-8
更新日期:1998-06-30 00:00:00
abstract::Catechol-O-methyltransferase (COMT) is a candidate gene for the pathogenesis of some psychiatric disorders. The aim of this study is to examine the role of the COMT gene Val158Met polymorphism on the clinical aspects of bipolar disorder including symptomatology and therapeutic response. This study comprised 144 unrela...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.psychres.2008.09.011
更新日期:2010-01-30 00:00:00
abstract::The DSM-IV describes pathological gambling as a chronic condition with an insidious course. However, several extant studies characterize pathological and problem gambling as fluctuating over time. The present analyses expand on previous reports by evaluating changes in pathological gambling symptoms across the lifetim...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.05.015
更新日期:2007-07-30 00:00:00
abstract::Past research has found that deficits in insight into illness are related to executive deficits in schizophrenia. This study further explores this relationship with the utilization of an ecologically-valid battery of executive tests. The study included 21 patients with schizophrenia who were administered the Behaviour...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.09.012
更新日期:2007-05-30 00:00:00
abstract::This investigation aimed to determine whether impaired insight influences the validity of self-report test scores in schizophrenia and schizoaffective disorder. 274 outpatients enrolled in work rehabilitation completed the Beck Depression Inventory (BDI), Eysenck Personality Questionnaire (EPQ), Bell Object Relations ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.04.012
更新日期:2007-05-30 00:00:00
abstract::This study examined the Montreal Cognitive Assessment (MoCA) as a neurocognitive screener and its relationship with functional outcomes in a sample of outpatients diagnosed with severe mental illness (SMI). The MoCA, Brief Assessment of Cognition in Schizophrenia (BACS), UCSD Performance-Based Skills Assessment Test-2...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.07.078
更新日期:2014-12-15 00:00:00
abstract::Endogenous opiates have been implicated as regulators of mood and pain. Recent literature suggests a relationship between these internal opiates and ingestive behaviors in both animals and humans. The present study investigates this relationship by comparing the pain sensitivities of obese and nonobese subjects. Twent...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(83)90099-9
更新日期:1983-02-01 00:00:00
abstract::There are some reports that catecholamines may modulate the production of monocytic cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF alpha). The present study was carried out in order to examine the effects of noradrenaline (10(-5), 10(-6) and 10(-7) M), clonidine (10(-5), 10(-6) and 10(-7) ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00216-x
更新日期:2000-11-20 00:00:00
abstract::In this study, we evaluate the efficacy and safety of interpersonal psychotherapy (IPT) for adolescents with depression. We searched our existing database and electronic databases, including PubMed, Cochrane, EMBASE, PsycINFO, Web of Science, and CINAHL databases (from inception to May 2016). We included randomized co...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.psychres.2017.03.023
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Declarative memory disturbances, known to substantially contribute to cognitive impairment in schizophrenia, have previously been attributed to prefrontal as well as hippocampal dysfunction. AIMS:To characterize the role of prefrontal and mesolimbic/hippocampal dysfunction during memory encoding in schizoph...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.03.007
更新日期:2010-09-30 00:00:00
abstract::This study examines the relationships between internalized stigma, psychological well-being, and subjective well-being in a sample of people with mental illness. We conducted a cross-sectional study with 213 outpatients from the Spanish public social care network. The results showed that (a) internalized stigma was si...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.06.029
更新日期:2015-08-30 00:00:00
abstract::High variability in adaptive behavior in cognitively-able adults with autism spectrum disorder has been previously reported, and may be caused by the high prevalence of psychiatric comorbidity in this population. This study's goals were to examine self-reported psychiatric symptoms in students with ASD, and to identif...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.01.098
更新日期:2019-03-01 00:00:00
abstract::Childhood maltreatment history is a prevalent risk factor for substance use disorder and has lifelong adverse consequences on psychiatric wellbeing. The role of personality variations in determining childhood maltreatment-associated outcomes is poorly understood. This study sought to test neuroticism and agreeableness...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.07.010
更新日期:2018-10-01 00:00:00
abstract::The association between orbital frontal cortex (OFC) volume and aggression was investigated in an at-risk psychiatric population. Forty-one psychiatric patients were referred for magnetic resonance imaging and a standardized psychometric assessment of aggression (Lifetime History of Aggression-Revised). Nineteen match...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2008.03.007
更新日期:2009-03-31 00:00:00
abstract::A double-blind, randomised controlled pilot clinical trial was conducted to assess the potential effectiveness and safety of low-charge electrotherapy (LCE) for patients with schizophrenia. Bitemporal LCE (approximately 2.8 Joules) was administered three times a week. The Positive and Negative Syndrome Scale score was...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2018.12.143
更新日期:2019-02-01 00:00:00
abstract::Since many psychopathological traits seem to be related to Gambling Disorder (GD), impulsivity, alexithymia and dissociation could play a central role in gambling behaviors, particularly in pathological gambling. We test this hypothesis in four distinct samples of gamblers, three undergoing different types of treatmen...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.10.046
更新日期:2016-12-30 00:00:00
abstract::The present investigation examined the interactive effects of anxiety sensitivity and mindful attention in relation to anxiety and depressive symptoms and psychopathology among 145 adult Latinos (85.5% female; Mage=39.9, SD=10.8 and 98.6% used Spanish as their first language) who attended a community-based primary hea...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.07.026
更新日期:2015-09-30 00:00:00
abstract::Schizophrenia is a highly heritable psychiatric disorder often associated with dopamine-related genetic variations. Thus, we performed a case-control study in 1504 Han Chinese population to evaluate the association of DRD1, DRD2 and DRD3 polymorphisms with schizophrenia. No statistically significant difference in alle...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.08.052
更新日期:2016-11-30 00:00:00
abstract::It has been shown that the dysfunction of N-methyl-d-asparate (NMDA) receptors-mediated neurotransmission plays a role in the pathophysiology of schizophrenia. Especially, GluN2B, a subunit of NMDA receptors, associated trafficking complex is altered in the prefrontal cortex of schizophrenia. The kinesin superfamily m...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.09.031
更新日期:2015-12-15 00:00:00
abstract::A variable number of tandem repeats (VNTR) in the second intron of the serotonin transporter gene (STin2) has been studied in association with the susceptibility to affective disorders. Recently, it was reported that selective serotonin reuptake inhibitors were more effective in patients with major depressive disorder...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(02)00141-5
更新日期:2002-08-30 00:00:00
abstract::Little is known about the effects of recurring depressive episodes on cognition and behavior. The objective of the study was to compare cognitive function and depression-related behavior between healthy female subjects and female outpatients with early-onset DSM-IV recurrent major depressive disorder and to investigat...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2003.12.004
更新日期:2004-02-15 00:00:00
abstract::The purpose of the present study is to evaluate the prevalence of intermittent explosive disorder (IED) as well as its comorbidity with other mental disorders in a Japanese community sample. Subjects were 4,134 residents in selected sites in Japan. Diagnoses of mental disorders are based on the World Mental Health Sur...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.07.018
更新日期:2011-04-30 00:00:00
abstract::A COVID-19 epidemic has been spreading in China and other parts of the world since December 2019. The epidemic has brought not only the risk of death from infection but also unbearable psychological pressure. We sampled college students from Changzhi medical college by using cluster sampling. They responded to a quest...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112934
更新日期:2020-05-01 00:00:00
abstract::Within the core promoter region of prodynorphin (PDYN), a 68-bp sequence was found to occur as a polymorphism element, either singular or as tandemly repeated two, three or four times. We report the sequence of a novel allele (5-repeats). Our study revealed the existence of an ancestral nucleotide (A) at 29th position...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.06.048
更新日期:2014-11-30 00:00:00
abstract:BACKGROUND:High suicide attempt (SA) rates have been reported in first-episode psychosis (FEP) patients, particularly during the first year after the illness onset. Despite previous studies establishing several risk factors for suicidal behaviour in FEP, premorbid personality and social cognition have not been sufficie...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.05.050
更新日期:2017-10-01 00:00:00
abstract::The distribution of platelet monoamine oxidase (MAO) activity is examined in a large cohort of 18-year-olds from a college setting. A mixture of three distributions is needed to describe the data, even when a power transformation is used to remove skewness in the distribution. This is compatible with MAO activity bein...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(82)90069-5
更新日期:1982-12-01 00:00:00
abstract::Excessive interpersonal dependency has been described in depression and addictive disorders. Moreover, excessive dependency and suicidality are linked in psychiatric subjects, but their relationships have not been studied in specific addictions. Separate samples of female anorectic patients (n=150), female bulimic pat...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.06.022
更新日期:2005-11-15 00:00:00
abstract::Numerous evidence indicated mitochondrial abnormalities in the pathophysiology of bipolar disorder (BD); however, it remains unclear whether aberrant mitochondrial DNA (mtDNA) copy number (cn) occur in BD due to the conflicting results in previous studies. Here, peripheral blood mtDNAcn in 69 BD patients and 54 contro...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.psychres.2018.08.014
更新日期:2018-11-01 00:00:00
abstract::As they alleviate major depressive disorder, antidepressant therapies may improve associated sleep disturbances, but may also have inherent sedating or activating properties. We examined sleep changes during a multicenter, sham-controlled, trial of transcranial magnetic stimulation (TMS) therapy for pharmacoresistant ...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.psychres.2012.09.011
更新日期:2013-01-30 00:00:00
abstract::Lithium is among the best proven treatments for patients diagnosed with Bipolar Disorder, however response to Lithium appears to be considerably variable among individuals and it has been suggested that this inconstancy in Lithium response could be genetically determined. Starting from this perspective, in the last fe...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.05.036
更新日期:2019-08-01 00:00:00