Abstract:
:This study examined the Montreal Cognitive Assessment (MoCA) as a neurocognitive screener and its relationship with functional outcomes in a sample of outpatients diagnosed with severe mental illness (SMI). The MoCA, Brief Assessment of Cognition in Schizophrenia (BACS), UCSD Performance-Based Skills Assessment Test-2 (UPSA-2), and Global Assessment of Functioning (GAF) were administered to 28 SMI patients and 18 non-psychiatric controls. Patients obtained significantly lower scores on the MoCA, BACS, UPSA-2, and GAF compared to non-patients. The cutoff score <26 of the MoCA resulted in favorable sensitivity (89%) but lower specificity (61%) in classification of SMI patients. The MoCA was significantly correlated with UPSA scores but not GAF scores, whereas the BACS was not significantly correlated with UPSA or GAF scores. When entered into hierarchical regression analyses, the MoCA accounted for significant variance in UPSA scores above variance accounted for by the BACS. Both the MoCA and the BACS contributed unique variance in GAF scores. Overall, the MoCA demonstrated high sensitivity as a cognitive screener in SMI. Moreover, MoCA scores were related to performance-based measures of functional capacity.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Musso MW,Cohen AS,Auster TL,McGovern JEdoi
10.1016/j.psychres.2014.07.078subject
Has Abstractpub_date
2014-12-15 00:00:00pages
664-8issue
1-2eissn
0165-1781issn
1872-7123pii
S0165-1781(14)00657-Xjournal_volume
220pub_type
杂志文章abstract::The aim of the current study was to explore the associations between changes in the number of binges, physical activity participation, physical fitness, physical self-perception and quality of life following a 6-month physical activity counseling and cognitive behavioral program in patients with binge eating disorder ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.05.016
更新日期:2014-10-30 00:00:00
abstract::To explore changes in immune cell status with changes in the hypothalamic-pituitary (HP) axis in 20 patients with major depression as compared with 20 age-, sex-, and race-matched control subjects, we examined peripheral blood mononuclear cells (PBMC) for total T-cells (T3), total B-cells (B1), two T-cell subsets (T4 ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(88)90048-0
更新日期:1988-08-01 00:00:00
abstract::Both psychiatric disorders and psychiatric drug treatments produce changes of psychomotor performance which can disturb and/or interfere with the ability to drive safely. We studied the influence of current psychiatric drug treatments on psychomotor functions and on driving performance of 77 consecutive psychiatric ou...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.02.013
更新日期:2010-04-30 00:00:00
abstract::Lithium is among the best proven treatments for patients diagnosed with Bipolar Disorder, however response to Lithium appears to be considerably variable among individuals and it has been suggested that this inconstancy in Lithium response could be genetically determined. Starting from this perspective, in the last fe...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.05.036
更新日期:2019-08-01 00:00:00
abstract::Autobiographical amnesia assessments in depression need to account for normal changes in consistency over time, contribution of mood and type of memories measured. We report herein validation studies of the Columbia Autobiographical Memory Interview - Short Form (CAMI-SF), exclusively used in depressed patients receiv...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.12.010
更新日期:2012-05-15 00:00:00
abstract::The present follow-up study examines the associations between cognition and parent-rated internalizing problems among adolescents with early-onset schizophrenia (EOS) at baseline (T1) and self-rated internalizing problems 13 years later (T2). Twelve individuals (8 male/4 female) with EOS and 30 healthy controls (16 ma...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.033
更新日期:2018-07-01 00:00:00
abstract::To assess predictors of the diagnosis of bipolar disorder is important since it is known that the early diagnosis is associated with a better response to the treatment. Thus, the aim of this systematic review is to assess the role of the suicide risk in the diagnosis conversion to bipolar disorder. We searched Pubmed,...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.026
更新日期:2018-10-01 00:00:00
abstract::Executive functions play an important role in problem-solving and self-control. Set-shifting is an aspect of executive functioning and represents cognitive flexibility. The inability to control eating in Binge Eating Disorder (BED) may imply deficits in set-shifting which could be exacerbated by negative mood and depr...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2015.09.001
更新日期:2015-12-15 00:00:00
abstract::Hypersomnia is common in psychiatric disorders, yet there are few self-report measures that adequately characterize this sleep disturbance. The objective of this study was to validate the Hypersomnia Severity Index (HSI), a tool designed to measure severity, distress and impairment of hypersomnia in psychiatric popula...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112547
更新日期:2019-11-01 00:00:00
abstract::Theory of Mind (ToM) is the ability to correctly determine the intentions and behaviours of others. It is known that this capability is compromised in individuals with schizophrenia. It is has not been fully elucidated whether this observed phenomenon is of a state or trait nature. This study investigated whether ToM ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.01.008
更新日期:2006-09-30 00:00:00
abstract::Most people with a serious mental illness experience significant functional impairment despite ongoing pharmacological treatment. Thus, in order to improve outcomes, a better understanding of functional predictors is needed. This study examined negative affect, a construct comprised of negative emotional experience, a...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.06.031
更新日期:2016-09-30 00:00:00
abstract::Depressive patients exhibit symptoms of impaired regulation of wakefulness with hyperarousal and agitation as well as difficulties to falling asleep and preserving sleep continuity. Changes in hypocretin (hcrt) levels as polypeptides with impact on arousal and sleep-wake-regulation have been discussed in affective dis...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.06.004
更新日期:2011-12-30 00:00:00
abstract::Depression is a common illness which tends to have a relapsing progression. Revealing vulnerability factors is an important step towards improved treatment and prevention. Previous studies of individuals in remission indicate that inhibitory control is more strongly impaired than other cognitive functions. Studies hav...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.11.038
更新日期:2016-01-30 00:00:00
abstract::Perinatal depression/anxiety is considered the most underdiagnosed pregnancy complication in the US and is associated with poor maternal and fetal outcomes. However, despite its prevalence, most women who present with depressive symptoms are not screened and do not receive adequate treatment. We examined the clinical ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.12.077
更新日期:2019-02-01 00:00:00
abstract::Over the years, schizophrenia is speculated to be associated with immune or inflammatory reactions mediated by cytokines. It is proposed that chronic inflammation might damage the micro-vascular system of brain and hamper cerebral blood flow. Scientific evidence suggests that an increase of stress hormone like norepin...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2014.02.004
更新日期:2014-05-15 00:00:00
abstract::Understanding what happens at first onset of auditory verbal hallucinations (AVHs) is extremely important on a clinical and theoretical level. Previous studies have only focused on age with regard to first onset of AVHs. In the current epidemiological study, we examined a number of aspects relating to first onset of A...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.12.060
更新日期:2018-03-01 00:00:00
abstract::The object of this study was to determine the reproducibility of the measurement of plasma catecholamine metabolites in normal control subjects and to assess the influence of factors such as time of day, diet, activity, blood pressure, and mood on the variance of these measures. Plasma free homovanillic acid (HVA), 3-...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(88)90001-7
更新日期:1988-02-01 00:00:00
abstract::This report explores the relationship between age of first onset of major depression and other demographic and clinical features in the first 1500 patients entering the Sequenced Treatment Alternative to Relieving Depression (STAR*D) study. Outpatients, 18-75 years of age, with nonpsychotic major depressive disorder (...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.07.004
更新日期:2004-12-15 00:00:00
abstract::Prior studies have confirmed a bias against disconfirmatory evidence (BADE) in schizophrenia which has been associated with delusions. However, its role in the pathogenesis of psychosis is yet unclear. The objective was to investigate BADE for the first time in subjects with an at-risk-mental-state for psychosis (ARMS...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.02.028
更新日期:2016-04-30 00:00:00
abstract::In mental health services research, analyzing service utilization data often poses serious problems, given the presence of substantially skewed data distributions. This article presents a non-technical introduction to statistical methods specifically designed to handle the complexly distributed datasets that represent...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2007.07.003
更新日期:2008-08-15 00:00:00
abstract::Medication non adherence in schizophrenia is a major cause of relapse and hospitalization and remains for clinicians an important challenge. This study investigates the associations between insight, therapeutic alliance, perceived trauma related to psychiatric treatment and medication adherence in patients with schizo...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.07.063
更新日期:2017-11-01 00:00:00
abstract::Cognitive-behavioural therapy (CBT) is the recommended treatment for binge eating, yet many individuals do not recover, and innovative new treatments have been called for. The current study compares traditional CBT with two augmented versions of CBT; schema therapy, which focuses on early life experiences as pivotal i...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2016.04.080
更新日期:2016-06-30 00:00:00
abstract::Baseline 8 a.m. adrenocorticotropic hormone (ACTH) and cortisol levels and the postdexamethasone ACTH/cortisol values at 8 a.m. and 4 p.m. were determined in 86 depressed females diagnosed using DSM-III criteria. Postdexamethasone ACTH and cortisol values were significantly correlated with their baseline levels. We ha...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(90)90013-u
更新日期:1990-11-01 00:00:00
abstract::We assessed the course of psychiatric disorders in 23 cervical dystonia patients by using the structured clinical interview for DSM-IV and different rating scales. Patients were studied on two occasions 5 years apart. There were no differences in psychiatric disorders and severity of psychiatric symptoms between the t...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.07.076
更新日期:2015-09-30 00:00:00
abstract::The current study examined the interactive effects of Anxiety Sensitivity (AS) and menstrual cycle phase in the experience of menstrual-related symptoms. Participants were 55 community women who completed prospective tracking of menstrual-related symptoms across at least one full menstrual cycle using the Daily Record...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.07.016
更新日期:2013-12-15 00:00:00
abstract::Both personality traits and autonomic functioning show as gender differences, but their relationship is not well understood. Medically unexplained symptoms are related to personality features and can be assessed by autonomic measurement. The patterns are hypothesised to identify gender differences. We recruited 30 mal...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.01.031
更新日期:2013-10-30 00:00:00
abstract::Repetitive transcranial magnetic stimulation (rTMS) is currently undergoing active investigation for use in the treatment of major depression. Recent research has indicated that current methods used to localize the site of stimulation in dorsolateral prefrontal cortex (DLPFC) are significantly inaccurate. However, lit...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.pscychresns.2006.04.006
更新日期:2006-11-22 00:00:00
abstract::Two studies have shown that increasing the consultation of the word "suicide" in the Google search engine was associated with a subsequent increase in the prevalence of suicide attempts. The main goal of this article was to explore the trends generated by a key-word search associated with suicide, depression and bipol...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.04.022
更新日期:2015-08-30 00:00:00
abstract::Reliable quantitative ratings of chronic medical illness burden have proved to be difficult in geropsychiatric practice and research. Thus, the purpose of the study was to demonstrate the feasibility and reliability of a modified version of the Cumulative Illness Rating Scale (CIRS; Linn et al., 1968) in providing qua...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(92)90005-n
更新日期:1992-03-01 00:00:00
abstract::Childhood adversity is associated with a range of mental disorders, functional impairment and higher health care costs in adulthood. In this study we evaluated if childhood adversity was predictive of adverse clinical and functional outcomes and health care costs in a sample of patients at ultra-high risk (UHR) for de...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.psychres.2016.11.014
更新日期:2017-01-01 00:00:00