Abstract：
:Baseline 8 a.m. adrenocorticotropic hormone (ACTH) and cortisol levels and the postdexamethasone ACTH/cortisol values at 8 a.m. and 4 p.m. were determined in 86 depressed females diagnosed using DSM-III criteria. Postdexamethasone ACTH and cortisol values were significantly correlated with their baseline levels. We have shown that regression analysis should be used to assess dexamethasone-induced changes as the residual ACTH and cortisol responses, with the relative effects of the baseline data on the hormone responses being partialed out. The residual ACTH and cortisol values were significantly increased in the most severely depressed females as compared to minor depressives. The residual ACTH responses were markedly correlated with the residual cortisol responses. Cortisol nonsuppression during a depressive episode appeared to be determined by an augmented ACTH escape from dexamethasone suppression. The residual ACTH and cortisol responses could prove to be the most sensitive reflection of the disorder in the negative feedback by dexamethasone on the pituitary. In clinical practice, the ratio ln (postdexamethasone ACTH): ln (basal ACTH) can be used, since this ratio is linearly correlated with the residual ACTH responses.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Maes M,Vandewoude M,Schotte C,Maes L,Martin M,Blockx Pdoi
10.1016/0165-1781(90)90013-usubject
Has Abstractpub_date
1990-11-01 00:00:00pages
107-26issue
2eissn
0165-1781issn
1872-7123pii
0165-1781(90)90013-Ujournal_volume
34pub_type
杂志文章abstract：:Depressive disorders are common, heterogeneous conditions involving physical and psychological symptoms, and substantial impairment in quality of life (QoL). However, relationships between depressive symptoms and QoL are poorly understood, and little research has directly compared relationships between subtypes of dep...
journal_title：Psychiatry research
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abstract：:Trait anxiety, a personality dimension, has been characterized by functional consequences such as increased distractibility, attentional bias in favor of threat-related information and hyper-responsive amygdala. However, literature on the association between resting state brain functional connectivity, as studied usin...
journal_title：Psychiatry research
pub_type： 杂志文章
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abstract：:The Veterans Outcomes Assessment (VOA) program surveys Veteran Health Administration (VHA) patients when they begin mental health treatment and at follow-up at three months to obtain patient-reported outcomes measures (PROM). It complements VA's evolving program in measurement-based care by providing additional data t...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2020-09-01 00:00:00
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(97)03028-x
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journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
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更新日期：2009-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113298
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journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(95)02474-b
更新日期：1995-10-16 00:00:00
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journal_title：Psychiatry research
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doi：10.1016/j.psychres.2016.11.038
更新日期：2017-01-01 00:00:00
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journal_title：Psychiatry research
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更新日期：2018-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.12.001
更新日期：2010-04-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：1989-05-01 00:00:00
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doi：10.1016/0165-1781(90)90002-m
更新日期：1990-12-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.03.006
更新日期：2014-06-30 00:00:00
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journal_title：Psychiatry research
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更新日期：1996-02-28 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章,meta分析,评审
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更新日期：2006-11-22 00:00:00
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journal_title：Psychiatry research
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更新日期：2011-07-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2005.05.009
更新日期：2005-08-30 00:00:00
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journal_title：Psychiatry research
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更新日期：2016-12-30 00:00:00
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doi：10.1016/j.psychres.2012.04.018
更新日期：2012-12-30 00:00:00
abstract：:Patients with borderline personality disorder (BPD) suffer from various impairments in emotional functioning such as affective instability, inappropriate anger and unstable relationships. These deficits may influence two fundamental motivational systems, the behavioral inhibition system (BIS) and behavioral activation...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.04.027
更新日期：2014-08-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2013-01-30 00:00:00
abstract：:Clinical research across the developmental spectrum increasingly reveals the nuanced ways in which emotion and cognition can work to either support or derail rational (i.e., healthy or goal-consistent) decision making. However, psychological theories offer discrepant views on how these processes interact, and on wheth...
journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2019.01.048
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Intimate partner violence (IPV) is defined as physical or sexual violence, emotional abuse and stalking. It is typically experienced by women but can also be experienced by men. During quarantine due to the COVID-19, home risks to become a very dangerous place for victims of domestic violence. METHOD:Very r...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113046
更新日期：2020-04-30 00:00:00
abstract：:Post-traumatic stress disorder (PTSD) may occur after exposure to stressful, fearful or troubling events. Until now, there is no curable medication for this disorder. Cerebrolysin is a neuropeptide, which has an important role in the treatment of vascular dementia. In this study, the probable protective effect of cere...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.10.008
更新日期：2018-12-01 00:00:00
