Abstract：
:Most people with a serious mental illness experience significant functional impairment despite ongoing pharmacological treatment. Thus, in order to improve outcomes, a better understanding of functional predictors is needed. This study examined negative affect, a construct comprised of negative emotional experience, as a predictor of social functioning across serious mental illnesses. One hundred twenty-seven participants with schizophrenia, 113 with schizoaffective disorder, 22 with psychosis not otherwise specified, 58 with bipolar disorder, and 84 healthy controls (N=404) completed self-report negative affect measures. Elevated levels of negative affect were observed in clinical participants compared with healthy controls. For both clinical and healthy control participants, negative affect measures were significantly correlated with social functioning, and consistently explained significant amounts of variance in functioning. For clinical participants, this relationship persisted even after accounting for cognition and positive/negative symptoms. The findings suggest that negative affect is a strong predictor of outcome across these populations and treatment of serious mental illnesses should target elevated negative affect in addition to cognition and positive/negative symptoms.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Grove TB,Tso IF,Chun J,Mueller SA,Taylor SF,Ellingrod VL,McInnis MG,Deldin PJdoi
10.1016/j.psychres.2016.06.031subject
Has Abstractpub_date
2016-09-30 00:00:00pages
198-206eissn
0165-1781issn
1872-7123pii
S0165-1781(15)30386-3journal_volume
243pub_type
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