Failure to replicate linkage between chromosome 5q11-q13 markers and schizophrenia in 28 families.

Abstract:

:Sherrington et al. (1988) reported linkage between markers located on the 5q11-q13 region of chromosome 5 and schizophrenia in five Icelandic and two British families. To date, however, all attempts to replicate the initial finding have failed. Using three markers of chromosome 5, we have studied 28 additional French pedigrees. When our data were analyzed both with parametric (i.e., lod scores) and nonparametric methods, we found no evidence of linkage. Thus, we were unable to replicate the earlier report by Sherrington et al.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Campion D,d'Amato T,Laklou H,Sabate O,Jay M,Leboyer M,Malafosse A,Gorwood P,Babron MC,Hillaire D

doi

10.1016/0165-1781(92)90021-t

subject

Has Abstract,Author List Incomplete

pub_date

1992-12-01 00:00:00

pages

171-9

issue

3

eissn

0165-1781

issn

1872-7123

pii

0165-1781(92)90021-T

journal_volume

44

pub_type

杂志文章
  • Searching for a structural endophenotype in psychosis using computational morphometry.

    abstract::Structural cerebral abnormalities are frequently observed in schizophrenia. These abnormalities may indicate vulnerability for the disorder, as evidenced by reports of familial clustering of measures identified through region-of-interest analyses using manual outlining procedures. We used computational morphometry to ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0925-4927(02)00125-7

    authors: Marcelis M,Suckling J,Woodruff P,Hofman P,Bullmore E,van Os J

    更新日期:2003-04-01 00:00:00

  • Differentiating suicide decedents who died using firearms from those who died using other methods.

    abstract::Studies have documented a link between gun ownership and suicide, but little is known about characteristics of those most likely to use a gun in a suicide attempt rather than alternative methods. We examined which factors differentiate suicide decedents who died using a gun from those who died by other methods. We fur...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.02.048

    authors: Anestis MD,Khazem LR,Anestis JC

    更新日期:2017-06-01 00:00:00

  • Treatment of severe mania with intravenous magnesium sulphate as a supplementary therapy.

    abstract::Ten patients with severe, therapy-resistant manic agitation received magnesium sulphate infusions with a continuous magnesium (Mg) flow of approximately 200 mg/h (4353+/-836 mg/day; daily monitored Mg plasma level: 2.44+/-0.34 mmol/l) for periods ranging from 7 to 23 days. Concomitant psychotropic treatment consisted ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(99)00107-9

    authors: Heiden A,Frey R,Presslich O,Blasbichler T,Smetana R,Kasper S

    更新日期:1999-12-27 00:00:00

  • Psychosis, lithium-induced antipsychotic response, and seasonality.

    abstract::Lithium alone has previously been shown to effect antipsychotic response in approximately one-quarter of mood incongruent psychoses. Such lithium-responsive psychoses and/or the antipsychotic effects of lithium appear to be seasonal, with maximal response rates occurring in the 3-month periods surrounding January and ...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章

    doi:10.1016/0165-1781(88)90122-9

    authors: Garver DL,Hutchinson LJ

    更新日期:1988-12-01 00:00:00

  • Cognitive bias modification in problem and pathological gambling using a web-based approach-avoidance task: A pilot trial.

    abstract::There is evidence that training addicted participants to implicitly avoid disorder-related stimuli by using a training version of the Approach-Avoidance Task (AAT) results in reduced substance consumption (i.e., Approach Bias Modification [AppBM]). The aim of the present web-based study was to investigate the feasibil...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2018.12.075

    authors: Wittekind CE,Bierbrodt J,Lüdecke D,Feist A,Hand I,Moritz S

    更新日期:2019-02-01 00:00:00

  • Adjustment disorder as proposed for ICD-11: Dimensionality and symptom differentiation.

    abstract::Although Adjustment Disorder as a diagnostic category is widely used in clinical practice it is critically discussed that it has not been conceptualized as a category with unique symptoms. Hence, the conceptualization of Adjustment Disorder is subject to substantive change in ICD-11 including core symptoms and additio...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.07.010

    authors: Glaesmer H,Romppel M,Brähler E,Hinz A,Maercker A

    更新日期:2015-10-30 00:00:00

  • Evaluation of a proposed hamster separation model of depression.

    abstract::Phodopus sungorus, the Siberian dwarf hamster, exhibits a number of reproducible and quantifiable behavioral changes when the members of a male-female pair bond are separated. Preliminary evaluation of the syndrome revealed a significant increase in body weight, decrease in social interaction, and decrease in explorat...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(84)90106-9

    authors: Crawley JN

    更新日期:1984-01-01 00:00:00

  • Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity.

    abstract::One of the central problems in posttraumatic stress disorder (PTSD) is the inability to suppress fear even under safe conditions. The neural underpinnings of fear are clinically relevant but poorly understood. This study assessed fear potentiation and fear inhibition using fear-potentiated startle in a conditional dis...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2007.12.014

    authors: Jovanovic T,Norrholm SD,Fennell JE,Keyes M,Fiallos AM,Myers KM,Davis M,Duncan EJ

    更新日期:2009-05-15 00:00:00

  • Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene.

    abstract::We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and th...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2008.02.012

    authors: Pasquini M,Fabbrini G,Berardelli I,Bonifati V,Biondi M,Berardelli A

    更新日期:2008-10-30 00:00:00

  • Thinking or doing? An examination of well-established suicide correlates within the ideation-to-action framework.

    abstract::Limited research has examined differences in well-established suicide correlates between individuals with various histories of suicidality within the ideation to action framework. We hypothesized that individuals without a history of elevated suicidality would exhibit lowest levels of suicide correlates (perceived bur...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.08.038

    authors: Khazem LR,Anestis MD

    更新日期:2016-11-30 00:00:00

  • Panic disorder respiratory subtype: a comparison between responses to hyperventilation and CO2 challenge tests.

    abstract::In this study 117 panic disorder patients were divided into a respiratory subtype group and a non-respiratory subtype group. The respiratory subtype patients were observed to be more sensitive to the 35% CO(2) inhalation challenge test and the hyperventilation test than the non-respiratory subtype patients. ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2007.07.015

    authors: Freire RC,Lopes FL,Valença AM,Nascimento I,Veras AB,Mezzasalma MA,de-Melo-Neto VL,Zin WA,Nardi AE

    更新日期:2008-01-15 00:00:00

  • Impairment of incidental memory for frequency in patients with obsessive-compulsive disorder.

    abstract::The aim of our study was to investigate whether patients with obsessive-compulsive disorder (OCD) have impaired incidental memory for frequency. Fifty-four subjects (27 OCD patients and 27 matched control subjects) performed a task assessing estimation of occurrence of previously heard words. Performance on this task ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(01)00322-5

    authors: Jurado MA,Junqué C,Vallejo J,Salgado P

    更新日期:2001-11-30 00:00:00

  • Visual hallucinations in schizophrenia investigated with functional magnetic resonance imaging.

    abstract::We investigated a 27-year old patient with paranoid schizophrenia. Brain activity related to visual hallucinations was found in higher visual areas corresponding to the content of the hallucinations (faces, bodies, scenes) and the hippocampus. We assume that the hippocampal activity is related to the retrieval of visu...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2007.09.004

    authors: Oertel V,Rotarska-Jagiela A,van de Ven VG,Haenschel C,Maurer K,Linden DE

    更新日期:2007-12-15 00:00:00

  • Role of REM sleep and dream variables in the prediction of remission from depression.

    abstract::To test the hypothesis that REM sleep and/or dreams contribute to overnight mood regulation, 61 subjects were tested on the Beck Depression Inventory (BDI), and for 3 nights of monitored sleep on two occasions, once close to, and 1 year after, a marital separation. Forty-nine percent of the variance in the follow-up B...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(98)00071-7

    authors: Cartwright R,Young MA,Mercer P,Bears M

    更新日期:1998-09-21 00:00:00

  • Basal ganglia volume in adults with Down syndrome.

    abstract::This study was designed to determine the effects of aging on the volume of the basal ganglia in individuals with Down syndrome (DS) and to examine the relationship between basal ganglia volumes, neuropsychological test performance, and dementia status in this population. Subjects were 32 adults with DS. Basal ganglia ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0925-4927(97)00011-5

    authors: Aylward EH,Li Q,Habbak QR,Warren A,Pulsifer MB,Barta PE,Jerram M,Pearlson G

    更新日期:1997-05-16 00:00:00

  • Platelet serotonin and serum cholesterol concentrations in suicidal and non-suicidal male patients with a first episode of psychosis.

    abstract::Suicidal behavior is a major health risk in psychiatric disorders, especially in schizophrenia, wherein up to 10% patients will commit suicide. However, the neurobiology of suicide is still unclear. Suicidality has been related to decreased central serotonergic (5-hydroxytryptamine, 5-HT) function and reduced choleste...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2006.08.012

    authors: Marcinko D,Pivac N,Martinac M,Jakovljević M,Mihaljević-Peles A,Muck-Seler D

    更新日期:2007-02-28 00:00:00

  • Switch the itch: a naturalistic follow-up study on the neural correlates of cognitive flexibility in obsessive-compulsive disorder.

    abstract::Obsessive-compulsive disorder (OCD) is a relatively common psychiatric disorder characterized by intrusive thoughts and behaviors that dominate daily living, like an itch patients cannot ignore. Deficits in executive functioning are common in OCD and are thought to be related to dysfunctional frontal-striatal systems....

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2012.12.006

    authors: Vriend C,de Wit SJ,Remijnse PL,van Balkom AJ,Veltman DJ,van den Heuvel OA

    更新日期:2013-07-30 00:00:00

  • Temporal changes in attention to sad and happy faces distinguish currently and remitted depressed individuals from never depressed individuals.

    abstract::Depression is associated with attentional biases for emotional information that are proposed to reflect stable vulnerability factors for the development and recurrence of depression. A key question for researchers is whether those who have recovered from depression also exhibit attentional biases, and if so, how simil...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.09.036

    authors: Soltani S,Newman K,Quigley L,Fernandez A,Dobson K,Sears C

    更新日期:2015-12-15 00:00:00

  • Stereologic analysis of the lateral geniculate nucleus of the thalamus in normal and schizophrenic subjects.

    abstract::Reduction of volume and neuronal number has been found in several association nuclei of the thalamus in schizophrenic subjects. Recent evidence suggests that schizophrenic patients exhibit abnormalities in early visual processing and that many of the observed perceptual deficits are consistent with dysfunction of the ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2006.11.003

    authors: Selemon LD,Begovic A

    更新日期:2007-05-30 00:00:00

  • An investigation of the effect of social reciprocity, social anxiety, and letter fluency on communicative behaviors in adults with autism spectrum disorder.

    abstract::In recent years, research focusing on childhood has reported that communication difficulties in autism spectrum disorder (ASD) are related to the social reciprocity difficulties inherent to ASD, as well as severe social anxiety and decreased verbal fluency. However, there have been no reports regarding these correlati...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113503

    authors: Kimura Y,Fujioka T,Jung M,Fujisawa TX,Tomoda A,Kosaka H

    更新日期:2020-12-01 00:00:00

  • Transcranial magnetic stimulation for auditory hallucinations in schizophrenia.

    abstract::It has been suggested that low frequency transcranial magnetic stimulation (TMS) over left temporo-parietal cortex may reduce the frequency and intensity of auditory hallucinations in schizophrenia. Sixteen patients with hallucinations, treatment-resistant for at least 2 months, were randomised into a placebo-controll...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.psychres.2004.03.005

    authors: McIntosh AM,Semple D,Tasker K,Harrison LK,Owens DG,Johnstone EC,Ebmeier KP

    更新日期:2004-06-30 00:00:00

  • Abnormal functional connectivity of habenula in untreated patients with first-episode major depressive disorder.

    abstract::Major depressive disorder (MDD) is associated with abnormalities in emotional/cognitive processing and low reward sensitivity. The habenula has a pivotal role in these processes that may contribute to depression. However, there has been little research on the abnormal connectivity between the habenula and whole brain ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.112837

    authors: Wu Z,Wang C,Ma Z,Pang M,Wu Y,Zhang N,Zhong Y

    更新日期:2020-01-31 00:00:00

  • Morningness-Eveningness questionnaire in bipolar disorder.

    abstract::The Morningness-Eveningness Questionnaire (MEQ) is among the most commonly used scales to measure chronotype. We aimed to evaluate psychometric properties and clinical correlates of MEQ in bipolar disorder. Patients with a clinical diagnosis of bipolar disorder (n = 53) answered questionnaires for chronotype (MEQ), mo...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.02.004

    authors: Kanagarajan K,Gou K,Antinora C,Buyukkurt A,Crescenzi O,Beaulieu S,Storch KF,Mantere O

    更新日期:2018-04-01 00:00:00

  • First-night effect in the chronic fatigue syndrome.

    abstract::Since the magnitude of the first-night effect has been shown to be a function of medical conditions and of settings in which polysomnographies are performed, it is essential to evaluate the habituation phenomenon in each case in order to determine the optimal recording methodology. A first-night effect was evidenced i...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(03)00185-9

    authors: Le Bon O,Minner P,Van Moorsel C,Hoffmann G,Gallego S,Lambrecht L,Pelc I,Linkowski P

    更新日期:2003-09-30 00:00:00

  • Machine learning algorithm accurately detects fMRI signature of vulnerability to major depression.

    abstract::Standard functional magnetic resonance imaging (fMRI) analyses cannot assess the potential of a neuroimaging signature as a biomarker to predict individual vulnerability to major depression (MD). Here, we use machine learning for the first time to address this question. Using a recently identified neural signature of ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2015.07.001

    authors: Sato JR,Moll J,Green S,Deakin JF,Thomaz CE,Zahn R

    更新日期:2015-08-30 00:00:00

  • Prevalence and risk factors of agitation in newly hospitalized schizophrenia patients in China: An observational survey.

    abstract::This multi-center observational study investigated the prevalence of agitation in newly hospitalized schizophrenia patients in China and its potential risk factors. It was performed in 2014 and covered 14 hospitals. Newly hospitalized patients with schizophrenia or suspected schizophrenia who met the diagnostic criter...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.02.065

    authors: Mi W,Zhang S,Liu Q,Yang F,Wang Y,Li T,Mei Q,He H,Chen Z,Su Z,Liu T,Xie S,Tan Q,Zhang J,Zhang C,Sang H,Chen W,Shi L,Li L,Shi Y,Guo L,Zhang H,Lu L

    更新日期:2017-07-01 00:00:00

  • Pseudoautosomal region in schizophrenia: linkage analysis of seven loci by sib-pair and lod-score methods.

    abstract::In a previous study, we reported a nonrandom segregation between schizophrenia and the pseudoautosomal locus DXYS14 in a sample of 33 sibships. That study has been extended by the addition of 16 new sibships from 16 different families. Data from six other loci of the pseudoautosomal region and of the immediately adjac...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(94)90083-3

    authors: d'Amato T,Waksman G,Martinez M,Laurent C,Gorwood P,Campion D,Jay M,Petit C,Savoye C,Bastard C

    更新日期:1994-05-01 00:00:00

  • Sexual functioning and experiences in young people affected by mental health disorders.

    abstract::The majority of mental disorders have their onset in late adolescence and early adulthood and this coincides with important stages of sexual development. Although sexual dysfunction is highly prevalent among people with mental health disorders, little is known about this topic among youth. This study aimed to evaluate...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.04.009

    authors: McMillan E,Adan Sanchez A,Bhaduri A,Pehlivan N,Monson K,Badcock P,Thompson K,Killackey E,Chanen A,O'Donoghue B

    更新日期:2017-07-01 00:00:00

  • Neuroleptic-induced defecation in rats as a model for neuroleptic dysphoria.

    abstract::Two groups of 32 rats were challenged in a well-habituated environment with haloperidol (0.5 mg/kg), haloperidol (0.1 mg/kg), domperidone (0.1 mg/kg), or saline to study the effect of these drugs on defecation--an index of emotionality--and voluntary movements in the 2 hours after the injection. The haloperidol-treate...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(93)90053-j

    authors: Sachdev P,Loneragan C,Westbrook F

    更新日期:1993-04-01 00:00:00

  • Cognitive impairments and low BDNF serum levels in first-episode drug-naive patients with schizophrenia.

    abstract::Evidence shows that BDNF may regulate activity-dependent forms of synaptic plasticity underlying learning and memory. Previous studies reported low BDNF levels and cognitive impairment in the early stage of schizophrenia. Our current study aimed to explore the association between serum BDNF and cognitive functions in ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.02.034

    authors: Man L,Lv X,Du XD,Yin G,Zhu X,Zhang Y,Soares JC,Yang XN,Chen X,Zhang XY

    更新日期:2018-05-01 00:00:00