Abstract：
:Standard functional magnetic resonance imaging (fMRI) analyses cannot assess the potential of a neuroimaging signature as a biomarker to predict individual vulnerability to major depression (MD). Here, we use machine learning for the first time to address this question. Using a recently identified neural signature of guilt-selective functional disconnection, the classification algorithm was able to distinguish remitted MD from control participants with 78.3% accuracy. This demonstrates the high potential of our fMRI signature as a biomarker of MD vulnerability.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Sato JR,Moll J,Green S,Deakin JF,Thomaz CE,Zahn Rdoi
10.1016/j.pscychresns.2015.07.001subject
Has Abstractpub_date
2015-08-30 00:00:00pages
289-91issue
2eissn
0165-1781issn
1872-7123pii
S0925-4927(15)30025-1journal_volume
233pub_type
杂志文章abstract：:Light falling on the retina is converted into an electrical signal which stimulates serotonin synthesis. Previous studies described an increase of plasma and CNS serotonin levels after bright light exposure. Ghrelin and leptin are peptide hormones which are involved in the regulation of hunger/satiety and are related ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.05.068
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abstract：:Several existing laboratory-based stress paradigms have significant shortcomings for assessing neurobiological correlates of stress in healthy volunteers and severely ill psychiatric patients. We have examined neuroendocrine effects of stress associated with the lumbar puncture (LP) procedure in drug-free depressed an...
journal_title：Psychiatry research
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doi：10.1016/0165-1781(88)90050-9
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abstract：:First-episode psychosis typically emerges during late adolescence or young adulthood, interrupting achievement of crucial educational, occupational, and social milestones. Recovery-oriented approaches to treatment may be particularly applicable to this critical phase of the illness, but more research is needed on the ...
journal_title：Psychiatry research
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abstract：:Diminished facial expressivity is a common feature of schizophrenia that interferes with effective interpersonal communication. This study was designed to determine if real-time visual feedback improved the ability of patients with schizophrenia to imitate and produce modeled facial expressions. Twenty patients with s...
journal_title：Psychiatry research
pub_type： 杂志文章
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abstract：:Executive functions play an important role in problem-solving and self-control. Set-shifting is an aspect of executive functioning and represents cognitive flexibility. The inability to control eating in Binge Eating Disorder (BED) may imply deficits in set-shifting which could be exacerbated by negative mood and depr...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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更新日期：2020-11-01 00:00:00
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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abstract：:Patients with obsessive-compulsive disorder (OCD) demonstrate an increased number of neurological soft signs as well as neuroanatomic abnormalities detected with modern imaging techniques. Quantitative analysis of eye movements has proved fruitful in investigations of other neuropsychiatric disorders with similar find...
journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(89)90148-0
更新日期：1989-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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更新日期：2019-02-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2009-02-28 00:00:00
abstract：:Emotion dysregulation and hyperreactivity are considered central features of Borderline Personality Disorder (BPD). We assumed that such emotion dysregulation is also reflected in increased crying behavior of these patients and, consequently, hypothesized that BPD patients (N = 62), compared to Cluster C personality d...
journal_title：Psychiatry research
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