Prevalence and risk factors of agitation in newly hospitalized schizophrenia patients in China: An observational survey.

Abstract:

:This multi-center observational study investigated the prevalence of agitation in newly hospitalized schizophrenia patients in China and its potential risk factors. It was performed in 2014 and covered 14 hospitals. Newly hospitalized patients with schizophrenia or suspected schizophrenia who met the diagnostic criteria of the International Statistical Classification of Diseases and Related Health Problems, 10th revision, were recruited. Agitation and related risk factors were evaluated by a questionnaire designed for the survey. General demographic data, disease characteristics, scores on schizophrenia rating scales and agitation rating scales (e.g., Positive and Negative Syndrome Scale-Excited Component [PANSS-EC] and Behavioral Activity Rating Scale [BARS]) were collected. Among the 1512 patients screened in the study, 1400 (92.59%) were eligible. According to the PANSS-EC and BARS, the prevalence of agitation was 60.92% (853 of 1400) and 59.00% (826 of 1400), respectively. The overall prevalence of agitation was 47.50% (665 of 1400). The most important risk factor of agitation was being aggressive at baseline (Modified Overt Aggression Scale score ≥4, odds ratio=6.54; 95% confidence interval=4.93-8.69). Other risk factors included a history of aggressive behavior, northern region of residence, involuntary hospitalization, disease severity, low level of education, living alone, being unemployed or retired.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Mi W,Zhang S,Liu Q,Yang F,Wang Y,Li T,Mei Q,He H,Chen Z,Su Z,Liu T,Xie S,Tan Q,Zhang J,Zhang C,Sang H,Chen W,Shi L,Li L,Shi Y,Guo L,Zhang H,Lu L

doi

10.1016/j.psychres.2017.02.065

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

401-406

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(16)31409-3

journal_volume

253

pub_type

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