Abstract:
:Event schemas, the conceptualization of past experience, in schizophrenic patients were examined based upon script theory. Forty schizophrenic patients and 40 age- and education-matched normal control subjects participated in this study. This experiment consisted of three tasks. In the recall task, subjects recalled a typical scenario of going to a formal restaurant. In the frequency judgment task, subjects determined whether the given events happen frequently, occasionally or rarely in a restaurant. In the sequencing task, the subjects put the randomly presented events in the correct order. The responses of the schizophrenic patients in the recall task, when compared with those of the normal control subjects, had significantly fewer concepts and a greater proportion of highest-frequency concepts. In addition, the sequence of their responses was less accurate than that of normal individuals. This abnormality is unlikely due primarily to a retrieval deficit (i.e. generating fewer concepts in the recall task) given that their performances on the frequency judgment and sequencing tasks, tasks that require less retrieval effort, were consistent with those of the recall task. These results suggest that event schemas in schizophrenic patients contain little detailed information and are incoherent in organization.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Chan AS,Chiu H,Lam L,Pang A,Chow LYdoi
10.1016/s0165-1781(99)00051-7subject
Has Abstractpub_date
1999-10-11 00:00:00pages
169-81issue
2-3eissn
0165-1781issn
1872-7123pii
S0165-1781(99)00051-7journal_volume
87pub_type
杂志文章abstract::Correlations between normalized regional cerebral metabolic rates for glucose, determined by positron emission tomography with 18F-2-fluoro-2-deoxy-D-glucose, were used to investigate functional associations between pairs of brain regions in 18 adult patients with primary obsessive-compulsive disorder (OCD) of childho...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0925-4927(91)90014-h
更新日期:1991-12-01 00:00:00
abstract::Evidence contributing to the understanding of neurobiological mechanisms underlying appetite dysregulation in anorexia nervosa draws heavily on separate lines of research into neuroendocrine and neural circuitry functioning. In particular, studies consistently cite elevated ghrelin and abnormal activation patterns in ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.04.015
更新日期:2014-08-30 00:00:00
abstract::The aim of the current study was to establish the prevalence of subthreshold body dysmorphic disorder (subthreshold-BDD) in a community sample of adolescents, and to compare disorder correlates in individuals with subthreshold-BDD to those with probable full-syndrome BDD (probable-BDD) and those without BDD (non-BDD)....
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.085
更新日期:2017-05-01 00:00:00
abstract::To test the clinical efficacy of low dose fluphenazine decanoate (1.25 mg to 5.0 mg biweekly), we carried out two separate experiments: (1) an open trial in 57 schizophrenic outpatients, lasting 6 months; (2) a double-blind, placebo-controlled discontinuation study in a subgroup of patients who maintained good remissi...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(79)90016-7
更新日期:1979-12-01 00:00:00
abstract::The covid-19 pandemic has heavily burdened healthcare systems throughout the world. We performed a rapid systematic review to identify, assess and summarize research on the mental health impact of the covid-19 pandemic on HCWs (healthcare workers). We utilized the Norwegian Institute of Public Health's Live map of cov...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113441
更新日期:2020-11-01 00:00:00
abstract::The interplay between Callous Unemotional Traits (CU) and Moral Disengagement (MD) was examined in a sample of 90 adolescents with Disruptive Behavior Disorders. Using a person-centered approach, three CU and MD configurations were identified, attesting the strong relationship between these two moral dimensions. Howev...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.08.043
更新日期:2017-12-01 00:00:00
abstract::The Mood and Anxiety Symptoms Questionnaire (MASQ) was developed to measure the symptom-dimensions of the tripartite model of anxiety and depression. A 30-item short adaptation of the MASQ (MASQ-D30) was previously developed and validated in adult psychiatric outpatients. The aim of the present study was to evaluate t...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.12.018
更新日期:2014-03-30 00:00:00
abstract::Seventeen obsessive-compulsive disorder (OCD) patients and 25 normal control subjects submitted 24-hour urine samples for measurement of urinary free cortisol (UFC). Thirteen of the 17 OCD patients submitted a second 24-hour urine collection after a 10-week trial of either clomipramine (n = 6) or placebo (n = 7). At b...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(90)90081-f
更新日期:1990-05-01 00:00:00
abstract::Conduct disorder (CD) symptom counts in preadolescent boys, and antisocial personality disorder (ASP) and childhood conduct disorder symptom counts in their parents, were used as dimensional measures of behavioral deviation. A significant correlation was found for CD and ASP symptom counts between the two parents and ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(93)90003-y
更新日期:1993-01-01 00:00:00
abstract::Research on neurobiological impairments in clinical and genetic high risk for developing psychosis individuals (CHR) has identified several brain abnormalities that impact both brain structure and function. The current review will discuss research examining brain abnormalities in clinical and genetic high risk for psy...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.02.009
更新日期:2019-07-01 00:00:00
abstract::Spouse abuse is listed as a V code in DSM-IV-TR and worthy of further clinical investigation, although research has focused predominantly on the victims of family violence rather than the batterers themselves. This study tests the hypotheses that (a) batterers have a neurocognitive bias favoring negative affect (aggre...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.12.013
更新日期:2010-04-30 00:00:00
abstract::The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to e...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.07.079
更新日期:2014-12-15 00:00:00
abstract::Individuals with anorexia nervosa (AN) and bulimia nervosa (BN) have alterations of measures of serotonin (5-HT) and dopamine (DA) function, which persist after long-term recovery and are associated with elevated harm avoidance (HA), a measure of anxiety and behavioral inhibition. Based on theories that 5-HT is an ave...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2012.06.010
更新日期:2013-02-28 00:00:00
abstract::Within the core promoter region of prodynorphin (PDYN), a 68-bp sequence was found to occur as a polymorphism element, either singular or as tandemly repeated two, three or four times. We report the sequence of a novel allele (5-repeats). Our study revealed the existence of an ancestral nucleotide (A) at 29th position...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.06.048
更新日期:2014-11-30 00:00:00
abstract::Evidence on mental illness stigma abounds yet little is known about public perceptions of intellectual disability. This study examined causal beliefs about intellectual disability and schizophrenia and how these relate to awareness of the condition and social distance. UK lay people aged 16+(N=1752), in response to vi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.06.019
更新日期:2016-09-30 00:00:00
abstract::The present study aimed to provide preliminary evaluation of the effectiveness of a brief CBT intervention focusing on relapse prevention and positive symptom in a Chinese first episode schizophrenia (FES) population. This randomized controlled trial recruited eighty outpatients with FES (as determined using the DSM-I...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2018.12.130
更新日期:2019-02-01 00:00:00
abstract::The results of the dexamethasone suppression test (DST) were compared to levels of 24-hour 3-methoxy-4-hydroxyphenylglycol (MHPG) in 60 patients with unipolar depression. DST nonsuppressors had significantly higher levels of MHPG than did DST suppressors. The possible implications of this finding are discussed. ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(88)90065-0
更新日期:1988-05-01 00:00:00
abstract::Gambling disorder (GD) frequently co-occurs with substance use disorders. However, the extent to which GD co-occurs with behavioral addictions (BAs) and the demographic, clinical, and personality correlates of comorbid GD and BA is largely unknown. The aims of the present research were to address this gap among people...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112763
更新日期:2020-02-01 00:00:00
abstract::The tryptophan catabolite (TRYCAT) pathway is induced by indoleamine 2,3-dioxygenase (IDO), which upon activation depletes plasma tryptophan (TRP) and increases the synthesis of TRYCATs. Both phenomena are associated with somatization and depression. The aims of this study are to examine whether disorders in the TRYCA...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.09.029
更新日期:2012-04-30 00:00:00
abstract::The goal of this study was to assess integrity of the cingulum bundle in patients diagnosed with first episode schizophrenia, chronic schizophrenia, and matched controls as well as to determine the relationship between diffusion measures of cingulum bundle integrity and severity of patients' delusions of reference. Pa...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.08.002
更新日期:2014-11-30 00:00:00
abstract::Brain functional asymmetry abnormalities have previously been reported in schizophrenia. In the present study, we hypothesized that the pattern of functional asymmetry in schizophrenia may differ between patients suffering from positive and negative symptoms. We examined the relationship between altered asymmetry of f...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2009.11.004
更新日期:2010-04-30 00:00:00
abstract::We examined the relationship between the cortisol response to stress and aggression in patients with attention deficit hyperactivity disorder (ADHD). Based on a report stating that only some of the patients with ADHD retain their hypothalamic-pituitary-adrenal axis reactivity to stress, we separately analyzed the rela...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.04.001
更新日期:2007-09-30 00:00:00
abstract::Controversy exists regarding the association of age with postdexamethasone serum cortisol levels. We evaluated this relationship in 95 patients with major depressive disorder and 49 healthy controls. Age and 8 a.m. postdexamethasone cortisol levels were not correlated among the healthy controls, but were positively as...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90036-2
更新日期:1984-11-01 00:00:00
abstract::The use of Internet has grown in the past number of years, including the increased application of various therapy programs for psychiatric patients which can be accessed online. Few studies investigating psychiatric patients' Internet use exist. Therefore, the aim of this study was to examine the number of psychiatric...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.12.037
更新日期:2015-03-30 00:00:00
abstract::The present study had two aims and used two different samples. The first aim was to determine if alexithymia and dependent personality disorder (DPD) are distinct or overlapping constructs. The second aim was to determine the specificity and the stability of the relationship between alexithymia and DPD. The first stud...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.11.062
更新日期:2015-02-28 00:00:00
abstract::Panic disorder (PD) and social phobia (SP) share many clinical, demographic and biological characteristics. To investigate the relationships between the two disorders, the responses to inhalation of a 35% carbon-dioxide (CO2) and 65% oxygen (O2) gas mixture were assessed. Sixteen patients with PD, 16 patients with SP,...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-1781(97)00038-3
更新日期:1997-06-16 00:00:00
abstract::We have previously reported that the activity in platelets of the important antioxidant enzyme glutathione peroxidase (GPx) is inversely correlated with computed tomographic (CT) measures of brain atrophy in a population of patients with chronic schizophrenia, suggesting that low GPx may be a vulnerability factor in t...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(90)90103-c
更新日期:1990-01-01 00:00:00
abstract::Borderline personality disorder (BPD) is a severe clinical condition characterised by different maladaptive traits such as impulsivity and affective lability. Mood and emotion dysregulation are core features of affective disorders. Indeed patients affected by mood disorder (MD) have a significantly higher prevalence o...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.09.010
更新日期:2012-07-30 00:00:00
abstract::Four groups of children referred for attention disorders, learning disorders, or both were blindly titrated at statistically equivalent dosage levels of methylphenidate and improved more or less equivalently on several measures of attentiveness (cognitive style tests and reaction time). Methylphenidate dosage needs, w...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(92)90093-i
更新日期:1982-10-01 00:00:00
abstract::This study examined compulsive sexual behavior (CSB) and psychopathology in a treatment-seeking sample of men in São Paulo, Brazil. Eighty-six men (26% gay, 17% bisexual, 57% heterosexual) who met diagnostic criteria for excessive sexual drive and sexual addiction completed assessments consisting of the Mini Internati...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.01.021
更新日期:2013-10-30 00:00:00