当前位置： SCI文献检索 > PSYCHIATRY RESEARCH期刊下所有文献 > Neuropsychological correlates of eye movement abnormalities in schizophrenic patients and their unaffected relatives.

Neuropsychological correlates of eye movement abnormalities in schizophrenic patients and their unaffected relatives.

Abstract：

:Impairments on neuropsychological and eye movement tasks have been demonstrated in schizophrenic patients and also reported in their unaffected relatives. However, it is not clear to what extent these phenotypes overlap. This study examined the relationship between specific eye movement and neuropsychological measures. The relationship between performance on eye movement and neuropsychological tasks was measured in 79 schizophrenic patients (63% from multiply affected families), 129 of their healthy first-degree relatives, and 72 normal controls. Antisaccade scores were correlated with most measures of neurocognitive functioning, and this correlation was strongest in schizophrenic patients in all cases. In the schizophrenic patients, but not their relatives or controls, the antisaccade distractibility error (ADE) score correlated significantly with current intelligence, verbal memory (immediate and delayed recall), and associative learning. In the case of crystallised IQ and delayed verbal memory, smaller correlations were present in unaffected relatives, although neither survived Bonferroni correction. Smooth pursuit performance was unrelated to any neuropsychological measure. Our study suggests that antisaccade errors are likely to represent part of a generalized neuropsychological deficit in schizophrenia.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Zanelli J,MacCabe J,Toulopoulou T,Walshe M,McDonald C,Murray R

doi

10.1016/j.psychres.2008.05.008

subject

Has Abstract

pub_date

2009-08-15 00:00:00

pages

193-7

issue

3

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(08)00159-5

journal_volume

168

pub_type

杂志文章

相关文献

PSYCHIATRY RESEARCH文献大全
  • No evidence of linkage between the dopamine D2 receptor gene and schizophrenia.

    abstract：:The antipsychotic effects of dopamine D2 receptor antagonists (neuroleptics) and the psychotomimetic effects of dopamine agonists suggest that a defect of the D2 receptor gene might be a factor in the etiology of schizophrenia. Fifteen families that contained several members suffering from schizophrenia were tested fo...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/0165-1781(94)90111-2

    authors： Hallmayer J,Maier W,Schwab S,Ertl MA,Minges J,Ackenheil M,Lichtermann D,Wildenauer DB

    更新日期：1994-08-01 00:00:00

  • Gambling disorder and comorbid behavioral addictions: Demographic, clinical, and personality correlates.

    abstract：:Gambling disorder (GD) frequently co-occurs with substance use disorders. However, the extent to which GD co-occurs with behavioral addictions (BAs) and the demographic, clinical, and personality correlates of comorbid GD and BA is largely unknown. The aims of the present research were to address this gap among people...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2020.112763

    authors： Tang KTY,Kim HS,Hodgins DC,McGrath DS,Tavares H

    更新日期：2020-02-01 00:00:00

  • Depression and social anxiety in help-seeking patients with an ultra-high risk for developing psychosis.

    abstract：:Knowledge on associations between ultra-high risk (UHR) for developing psychosis and on non-psychotic psychopathology in help-seeking populations is limited with respect to differences between male and female patients. The present study tests the hypothesis that both social anxiety and depression are highly prevalent ...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2013.01.012

    authors： Rietdijk J,Ising HK,Dragt S,Klaassen R,Nieman D,Wunderink L,Cuijpers P,Linszen D,van der Gaag M

    更新日期：2013-10-30 00:00:00

  • Course, outcome and diagnosis stability of early-onset schizophrenia in Yunnan Province, China-a three years follow-up study.

    abstract：:The aim of the study was to describe diagnostic stability and psychosocial outcomes of subjects with early-onset schizophrenia (EOS). All the subjects who had been hospitalized in the Department of Psychiatry of the First Affiliated Hospital of Kunming Medical University between January 2011 and July 2015 with the dia...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2018.11.013

    authors： Kang C,Zhou H,Yang J,Yang R,Sun N,Wang S,Yang C,Han D,Srihari VH

    更新日期：2019-01-01 00:00:00

  • How do socio-demographic and clinical factors interact with adherence attitude profiles in schizophrenia? A cluster-analytical approach.

    abstract：:Knowledge regarding socio-demographic and clinical risk factors of medication nonadherence does not always help in addressing adherence in individual patients. Classifying patients according to subjective adherence influencing factors may aid practitioners in choosing adequate strategies for improving medication adher...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2010.10.012

    authors： Beck EM,Cavelti M,Wirtz M,Kossowsky J,Vauth R

    更新日期：2011-05-15 00:00:00

  • Choline chloride effects on memory: correlation with the effects of physostigmine.

    abstract：:Choline chloride (2g q.i.d.) and placebo were admin stered to nine young adults in a placebo-drug-placebo design. Subjects took memory tests at the end of both placebo periods and at the end of the choline period. All nine subjects had participated in a previous study in which 1.0 mg of physostigmine infused over a 1-...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/0165-1781(80)90071-2

    authors： Mohs RC,Davis KL

    更新日期：1980-05-01 00:00:00

  • The road not taken: social vs. private comparisons in Asperger׳s syndrome and high functioning autism.

    abstract：:Evaluation of the outcomes of our decisions may instigate comparisons of our actual outcome with those of others (social comparisons) or comparisons with alternative outcomes of choices not made (private comparisons). Previous research has suggested a deficit in attention to social information among individuals with a...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2014.01.036

    authors： Dvash J,Ben-Zèev A,Noga A,Shamay-Tsoory S

    更新日期：2014-05-30 00:00:00

  • Brain activation during the perception of distorted body images in eating disorders.

    abstract：:Eating disorder (ED) patients have severe disturbances in the perception of body shape and weight. The authors investigated brain activation patterns during the perception of distorted body images in various subtypes of ED. Participants comprised 33 patients with EDs (11 with restricting-type anorexia nervosa (AN-R), ...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.pscychresns.2009.09.001

    authors： Miyake Y,Okamoto Y,Onoda K,Kurosaki M,Shirao N,Okamoto Y,Yamawaki S

    更新日期：2010-03-30 00:00:00

  • Neuropsychological frontal impairments and negative symptoms in schizophrenia.

    abstract：:Negative symptoms have been associated with frontal lobe dysfunction in schizophrenia. However, neuropsychological studies that evaluated the correlation between performance in tests sensitive to the dorsolateral prefrontal cortex (DLPFC) and negative symptoms have shown inconsistent results. Growing evidence has appe...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2006.03.002

    authors： Martino DJ,Bucay D,Butman JT,Allegri RF

    更新日期：2007-08-30 00:00:00

  • Paliperidone is associated with reduced risk of severe hepatic outcome in patients with schizophrenia and viral hepatitis: A nationwide population-based cohort study.

    abstract：OBJECTIVE:Paliperidone, a second-generation antipsychotic, has been found to have minimal hepatotoxicity in patients with schizophrenia. However, long-term hepatic outcome in patients with schizophrenia and viral hepatitis remains unclear. METHODS:Data obtained from the Taiwan National Health Insurance Research Databa...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2019.112597

    authors： Chang CH,Lane HY,Liu CY,Chen SJ,Lin CH

    更新日期：2019-11-01 00:00:00

  • Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: A study combining mismatch negativity and proton magnetic resonance spectroscopy.

    abstract：:Disturbances in the hippocampal glutamate (Glu)/N-methyl-d-aspartate (NMDA) system have been implicated in the pathophysiology of bipolar disorder (BD). Here we aim to provide a targeted integration of two measures of glutamatergic functioning in BD; the association between mismatch negativity (MMN) and in vivo hippoc...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.pscychresns.2015.05.002

    authors： Chitty KM,Lagopoulos J,Hickie IB,Hermens DF

    更新日期：2015-08-30 00:00:00

  • Disruption of saccade production during oculomotor tracking in schizophrenia and the use of its changes across target velocity as a discriminator of the disorder.

    abstract：:A clear measure of eye movement disorder (EMD) that reliably separated schizophrenic individuals from others would both give insight into the brain control of the disorder and provide an aid in diagnosis. In the present study, a detailed analysis was carried out of the interactions between the pursuit and saccadic com...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/0165-1781(92)90145-s

    authors： Mather JA,Neufeld RW,Merskey H,Russell NC

    更新日期：1992-07-01 00:00:00

  • Are predictors of future suicide attempts and the transition from suicidal ideation to suicide attempts shared or distinct: a 12-month prospective study among patients with depressive disorders.

    abstract：:Our study aimed to examine the interplay between clinical and social predictors of future suicide attempt and the transition from suicidal ideation to suicide attempt in depressive disorders. Sixty-six Malaysian inpatients with a depressive disorder were assessed at index admission and within 1 year for suicide attemp...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2014.08.055

    authors： Chan LF,Shamsul AS,Maniam T

    更新日期：2014-12-30 00:00:00

  • PTSD's factor structure and measurement invariance across subgroups with differing count of trauma types.

    abstract：:To investigate the effect of the count of traumatizing event (TE) types on post-trauma mental health, several studies have compared posttraumatic stress disorder (PTSD) severity between individuals experiencing one versus multiple TE types. However, the validity of these studies depends on the establishment of measure...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2018.03.065

    authors： Contractor AA,Caldas SV,Dolan M,Lagdon S,Armour C

    更新日期：2018-06-01 00:00:00

  • A comparison of xenon-133 and xenon-127 for the determination of regional cerebral blood flow measured by dynamic SPECT.

    abstract：:Phantom studies and cerebral blood flow (CBF) measurements in 11 normal subjects at rest were performed by single photon emission tomography (SPECT) with Xe-133 (16 mm full-width at half-maximum [FWHM] collimation) and Xe-127 (16 mm, 12 mm, and 9 mm FWHM collimation). The phantom results clearly illustrated the feasib...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：

    authors： Coppola R,Marenco S,Jones DW,Berman KF,Weinberger DR

    更新日期：1992-11-01 00:00:00

  • Symptomatic and functional outcomes of substance use disorder persistence 2 years after admission to a first-episode psychosis program.

    abstract：:Substance use disorders (SUD) in first-episode psychosis (FEP) are highly prevalent and linked with poor outcomes. However, most longitudinal studies investigating their impacts in FEP have not reported proportions of patients who ceased SUD. Our aim was to examine the influence of SUD course on functional and symptom...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2016.11.007

    authors： Abdel-Baki A,Ouellet-Plamondon C,Salvat É,Grar K,Potvin S

    更新日期：2017-01-01 00:00:00

  • Children and adolescents attempting to participate in a worldwide online depression screener.

    abstract：:Depression rates are increasing among minors. Internet is central to the lives of many minors, and many of them look online for depression information. This report describes minors who attempted to screen themselves for depression in a worldwide online study. Google Ads were used to recruit individuals to a multilingu...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2020.113250

    authors： Stephens TN,Tran MM,Bunge EL,Liu NH,Barakat S,Garza M,Leykin Y

    更新日期：2020-09-01 00:00:00

  • Probing the magnocellular and parvocellular visual pathways in facial emotion perception in schizophrenia.

    abstract：:Schizophrenia patients have well-established deficits in facial emotion perception, which contribute to their poor social functioning. A number of studies have related these deficits to a differential dysfunction in the magnocellular (M) versus parvocellular (P) visual pathway. We assessed 35 schizophrenia patients an...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2017.03.031

    authors： Jahshan C,Wolf M,Karbi Y,Shamir E,Rassovsky Y

    更新日期：2017-07-01 00:00:00

  • Abnormal relationships between the neural response to high- and low-calorie foods and endogenous acylated ghrelin in women with active and weight-recovered anorexia nervosa.

    abstract：:Evidence contributing to the understanding of neurobiological mechanisms underlying appetite dysregulation in anorexia nervosa draws heavily on separate lines of research into neuroendocrine and neural circuitry functioning. In particular, studies consistently cite elevated ghrelin and abnormal activation patterns in ...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.pscychresns.2014.04.015

    authors： Holsen LM,Lawson EA,Christensen K,Klibanski A,Goldstein JM

    更新日期：2014-08-30 00:00:00

  • Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture.

    abstract：:The limbic system plays an important role in regulating the hypothalamic-pituitary-adrenal (HPA) axis as well as aspects of emotion, and both neuroendocrine disturbance and increased negative emotionality are associated with risk for developing affective disorders. However, the extent to which the architecture of conn...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.pscychresns.2011.07.015

    authors： Madsen KS,Jernigan TL,Iversen P,Frokjaer VG,Mortensen EL,Knudsen GM,Baaré WF

    更新日期：2012-01-30 00:00:00

  • Mitochondrial DNA copy number of peripheral blood in bipolar disorder: The present study and a meta-analysis.

    abstract：:Numerous evidence indicated mitochondrial abnormalities in the pathophysiology of bipolar disorder (BD); however, it remains unclear whether aberrant mitochondrial DNA (mtDNA) copy number (cn) occur in BD due to the conflicting results in previous studies. Here, peripheral blood mtDNAcn in 69 BD patients and 54 contro...

    journal_title：Psychiatry research

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.psychres.2018.08.014

    authors： Yamaki N,Otsuka I,Numata S,Yanagi M,Mouri K,Okazaki S,Boku S,Horai T,Ohmori T,Shirakawa O,Sora I,Hishimoto A

    更新日期：2018-11-01 00:00:00

  • Clonidine stimulation in anorexia nervosa: growth hormone, cortisol, and beta-endorphin responses.

    abstract：:Clinical and biochemical findings link anorexia nervosa (AN) and primary effective disorders (PAD). Clonidine, an alpha 2-adrenoceptor agonist, has been shown to blunt growth hormone (GH) response and greatly lower plasma cortisol in PAD patients. We examined the GH, cortisol, and beta-endorphin (beta-EP) responses to...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/0165-1781(87)90120-x

    authors： Brambilla F,Lampertico M,Sali L,Cavagnini F,Invitti C,Maggioni M,Candolfi C,Panerai AE,Müller EE

    更新日期：1987-01-01 00:00:00

  • Compulsive sexual behavior and psychopathology among treatment-seeking men in São Paulo, Brazil.

    abstract：:This study examined compulsive sexual behavior (CSB) and psychopathology in a treatment-seeking sample of men in São Paulo, Brazil. Eighty-six men (26% gay, 17% bisexual, 57% heterosexual) who met diagnostic criteria for excessive sexual drive and sexual addiction completed assessments consisting of the Mini Internati...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2013.01.021

    authors： Scanavino Mde T,Ventuneac A,Abdo CH,Tavares H,do Amaral ML,Messina B,dos Reis SC,Martins JP,Parsons JT

    更新日期：2013-10-30 00:00:00

  • Prevalence and risk factors of agitation in newly hospitalized schizophrenia patients in China: An observational survey.

    abstract：:This multi-center observational study investigated the prevalence of agitation in newly hospitalized schizophrenia patients in China and its potential risk factors. It was performed in 2014 and covered 14 hospitals. Newly hospitalized patients with schizophrenia or suspected schizophrenia who met the diagnostic criter...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2017.02.065

    authors： Mi W,Zhang S,Liu Q,Yang F,Wang Y,Li T,Mei Q,He H,Chen Z,Su Z,Liu T,Xie S,Tan Q,Zhang J,Zhang C,Sang H,Chen W,Shi L,Li L,Shi Y,Guo L,Zhang H,Lu L

    更新日期：2017-07-01 00:00:00

  • Thinking or doing? An examination of well-established suicide correlates within the ideation-to-action framework.

    abstract：:Limited research has examined differences in well-established suicide correlates between individuals with various histories of suicidality within the ideation to action framework. We hypothesized that individuals without a history of elevated suicidality would exhibit lowest levels of suicide correlates (perceived bur...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2016.08.038

    authors： Khazem LR,Anestis MD

    更新日期：2016-11-30 00:00:00

  • Standardization of Brief Inventory of Social Support Exchange Network (BISSEN) in Japan.

    abstract：:This study describes the Brief Inventory of Social Support Exchange Network (BISSEN) as a standardized brief inventory measuring various aspects of social support. We confirmed the reliability and validity for function and direction of support and standardized the BISSEN. For Sample 1, a stratified random sampling met...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2017.03.056

    authors： Aiba M,Tachikawa H,Fukuoka Y,Lebowitz A,Shiratori Y,Doi N,Matsui Y

    更新日期：2017-07-01 00:00:00

  • Stability of sex differences by diagnosis in psychiatric hospitalizations.

    abstract：:We examined sex differences in the distribution of psychiatric diagnoses among hospitalized patients, controlling for socio-demographic variables. The sample included 1865 psychiatric inpatients consecutively admitted during a 9-year period. The finding of a higher proportion of men among patients hospitalized for sch...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2011.11.023

    authors： Martínez-Ortega JM,Jurado D,Gutiérrez-Rojas L,Molero P,Ramos MA,Gurpegui M

    更新日期：2012-06-30 00:00:00

  • Schizotypal personality and semantic functioning: Revisiting category fluency effects in a subclinical sample.

    abstract：:Semantic disturbances have been proposed as a possible cause of formal thought disorder in schizophrenia. Fluency tasks, in which volunteers are asked to produce as many exemplars as they can for a given category during one minute, are usually applied to the assessment of semantic processing. However, studies associat...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2018.11.074

    authors： Rodríguez-Ferreiro J,Aguilera M

    更新日期：2019-01-01 00:00:00

  • Serotonin 1A receptor gene, schizophrenia and bipolar disorder: an association study and meta-analysis.

    abstract：:Several investigations have reported associations between serotonin 1A (5-HT1A) receptor and major psychiatric disorders, such as schizophrenia and bipolar disorder (BP), making the 5-HT1A receptor gene (HTR1A) a good candidate gene for the pathophysiology of schizophrenia and BP. To evaluate the association between H...

    journal_title：Psychiatry research

    pub_type： 杂志文章

    doi：10.1016/j.psychres.2010.06.003

    authors： Kishi T,Okochi T,Tsunoka T,Okumura T,Kitajima T,Kawashima K,Yamanouchi Y,Kinoshita Y,Naitoh H,Inada T,Kunugi H,Kato T,Yoshikawa T,Ujike H,Ozaki N,Iwata N

    更新日期：2011-01-30 00:00:00

  • Effects of mindfulness-based stress reduction on anxiety symptoms in young people: A systematic review and meta-analysis.

    abstract：:In this study, we evaluated the efficacy of mindfulness-based stress reduction (MBSR) for young people with anxiety symptoms. We used many databases, including PubMed, PsycINFO, Web of Science, EMBASE, CINAHL and Cochrane Library (from inception to May 2019). We included randomized controlled trials (RCTs) comparing M...

    journal_title：Psychiatry research

    pub_type： 杂志文章,评审

    doi：10.1016/j.psychres.2020.113002

    authors： Zhou X,Guo J,Lu G,Chen C,Xie Z,Liu J,Zhang C

    更新日期：2020-07-01 00:00:00