Depression and social anxiety in help-seeking patients with an ultra-high risk for developing psychosis.

Abstract:

:Knowledge on associations between ultra-high risk (UHR) for developing psychosis and on non-psychotic psychopathology in help-seeking populations is limited with respect to differences between male and female patients. The present study tests the hypothesis that both social anxiety and depression are highly prevalent in an UHR population, particularly among women. From February 2008 to February 2010 baseline data were collected from help-seeking subjects (14-35 years) who were included in the Dutch Early Detection and Intervention Evaluation (EDIE-NL) trial. Two recruiting strategies were used: a two-stage screening strategy in a population of consecutive help-seeking and distressed subjects of secondary mental health services, and a referral strategy. This study included 201 patients with a mean age of 22.7 years. Of these, 102 (51%) were female, 58% of the patients met the criteria for clinical depression on the Beck Depression Inventory and 42% met the criteria for clinical social phobia on the Social Interaction Anxiety Scale. Women showed more depression and social anxiety than men. The results support the hypothesis that UHR is associated with depression and social anxiety, particularly in women. Screening a help-seeking population with depression and anxiety may be effective in detecting patients at UHR for developing psychosis.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Rietdijk J,Ising HK,Dragt S,Klaassen R,Nieman D,Wunderink L,Cuijpers P,Linszen D,van der Gaag M

doi

10.1016/j.psychres.2013.01.012

subject

Has Abstract

pub_date

2013-10-30 00:00:00

pages

309-13

issue

3

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(13)00033-4

journal_volume

209

pub_type

杂志文章
  • Targeting relapse prevention and positive symptom in first-episode schizophrenia using brief cognitive behavioral therapy: A pilot randomized controlled study.

    abstract::The present study aimed to provide preliminary evaluation of the effectiveness of a brief CBT intervention focusing on relapse prevention and positive symptom in a Chinese first episode schizophrenia (FES) population. This randomized controlled trial recruited eighty outpatients with FES (as determined using the DSM-I...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2018.12.130

    authors: Liu Y,Yang X,Gillespie A,Guo Z,Ma Y,Chen R,Li Z

    更新日期:2019-02-01 00:00:00

  • No evidence of linkage between the dopamine D2 receptor gene and schizophrenia.

    abstract::The antipsychotic effects of dopamine D2 receptor antagonists (neuroleptics) and the psychotomimetic effects of dopamine agonists suggest that a defect of the D2 receptor gene might be a factor in the etiology of schizophrenia. Fifteen families that contained several members suffering from schizophrenia were tested fo...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(94)90111-2

    authors: Hallmayer J,Maier W,Schwab S,Ertl MA,Minges J,Ackenheil M,Lichtermann D,Wildenauer DB

    更新日期:1994-08-01 00:00:00

  • The role of unhelpful metacognitive beliefs in psychosis: Relationships with positive symptoms and negative affect.

    abstract::The Self-Regulatory Executive Function (s-REF) model assumes that a common set of unhelpful metacognitive beliefs have a central role in predisposition to psychological disorder and the maintenance of symptoms and distress. This research aims to test whether the five unhelpful metacognitive beliefs implicated in the m...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.10.029

    authors: Sellers R,Gawęda Ł,Wells A,Morrison AP

    更新日期:2016-12-30 00:00:00

  • Between- and within-scanner variability in the CaliBrain study n-back cognitive task.

    abstract::Psychiatric neuroimaging techniques are likely to improve understanding of the brain in health and disease, but studies tend to be small, based in one imaging centre and of unclear generalisability. Multicentre studies have great appeal but face problems if functional magnetic resonance imaging (fMRI) data from differ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2010.08.010

    authors: Gradin V,Gountouna VE,Waiter G,Ahearn TS,Brennan D,Condon B,Marshall I,McGonigle DJ,Murray AD,Whalley H,Cavanagh J,Hadley D,Lymer K,McIntosh A,Moorhead TW,Job D,Wardlaw J,Lawrie SM,Steele JD

    更新日期:2010-11-30 00:00:00

  • State-related thalamic changes during antipsychotic treatment in schizophrenia: preliminary observations.

    abstract::Thalamic volumes and psychotic symptoms were assessed during psychotic exacerbation and during antipsychotic drug treatment. Reduction of psychotic symptoms (SAPS) during four weeks of treatment was highly correlated with volumetric expansion as measured by magnetic resonance imaging in both left and right thalamus [r...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0925-4927(03)00092-1

    authors: Strungas S,Christensen JD,Holcomb JM,Garver DL

    更新日期:2003-10-30 00:00:00

  • Association study of polymorphisms in the alpha 7 nicotinic acetylcholine receptor subunit and catechol-o-methyl transferase genes with sensory gating in first-episode schizophrenia.

    abstract::The purpose of the current study was to explore the association of auditory P50 sensory gating (P50) and prepulse inhibition (PPI) of schizophrenia with polymorphisms in the CHRNA7 and COMT genes. One hundred and fourty patients with schizophrenia participated in this study. They were administered the tests P50 and PP...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2013.03.027

    authors: Liu X,Hong X,Chan RC,Kong F,Peng Z,Wan X,Wang C,Cheng L

    更新日期:2013-10-30 00:00:00

  • Associations between trait anhedonia and emotional memory deficits in females with schizophrenia versus major depression.

    abstract::Individuals with schizophrenia (SZ) and individuals with major depressive disorder (MDD) demonstrate impaired emotional memory and decreased enjoyment of pleasant experiences (e.g., anhedonia). However, it is unclear whether these impairments reflect similar or different processes in the two diagnostic groups. This st...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.09.012

    authors: Olsen EK,Bjorkquist OA,Bodapati AS,Shankman SA,Herbener ES

    更新日期:2015-12-15 00:00:00

  • What is the prevalence of autism spectrum disorder and ASD traits in psychosis? A systematic review.

    abstract::There is increasing evidence to suggest both a symptomatic overlap and a clinically significant degree of co-occurrence between Autism Spectrum Disorders (ASD) and psychotic disorders such as schizophrenia but the nature of such relationships remain unclear. We reviewed the literature reporting prevalence rates of Aut...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审

    doi:10.1016/j.psychres.2017.01.017

    authors: Kincaid DL,Doris M,Shannon C,Mulholland C

    更新日期:2017-04-01 00:00:00

  • Decreased cardiac MIBG uptake, its correlation with clinical symptoms in dementia with Lewy bodies.

    abstract::Recent studies have demonstrated the usefulness of 123I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy for the diagnosis of dementia with Lewy bodies (DLB). In this study, we investigated the relationship between decreased cardiac MIBG uptake and clinical symptoms in DLB. Thirty-six patients with probable DLB...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2009.02.006

    authors: Kobayashi S,Tateno M,Morii H,Utsumi K,Saito T

    更新日期:2009-10-30 00:00:00

  • Managing major depressive disorder through the use of adjunct therapies.

    abstract::Although many treatments for Major Depressive Disorder (MDD) exist, only half of all patients respond to initial trial of pharmacotherapy and only a third will achieve remission with that trial. First-line therapies for the management of MDD include psychotherapy or pharmacotherapy, alone or in combination. Given the ...

    journal_title:Psychiatry research

    pub_type: 社论

    doi:10.1016/S0165-1781(14)70001-0

    authors: Katzman MA

    更新日期:2014-12-01 00:00:00

  • Differences of cerebral activation between superior and inferior learners during motor sequence encoding and retrieval.

    abstract::Cerebral activation during memory encoding and retrieval might depend on subjects' learning capacity, either by corresponding to better performance in superior learners or by reflecting increased effort in inferior learners. To investigate these alternative hypotheses, the study compared cerebral activation during enc...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2004.01.007

    authors: Heun R,Freymann N,Granath DO,Stracke CP,Jessen F,Barkow K,Reul J

    更新日期:2004-11-15 00:00:00

  • Cingulum bundle diffusivity and delusions of reference in first episode and chronic schizophrenia.

    abstract::The goal of this study was to assess integrity of the cingulum bundle in patients diagnosed with first episode schizophrenia, chronic schizophrenia, and matched controls as well as to determine the relationship between diffusion measures of cingulum bundle integrity and severity of patients' delusions of reference. Pa...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2014.08.002

    authors: Fitzsimmons J,Schneiderman JS,Whitford TJ,Swisher T,Niznikiewicz MA,Pelavin PE,Terry DP,Mesholam-Gately RI,Seidman LJ,Goldstein JM,Kubicki M

    更新日期:2014-11-30 00:00:00

  • Efficacy and acceptability of interpersonal psychotherapy for depression in adolescents: A meta-analysis of randomized controlled trials.

    abstract::In this study, we evaluate the efficacy and safety of interpersonal psychotherapy (IPT) for adolescents with depression. We searched our existing database and electronic databases, including PubMed, Cochrane, EMBASE, PsycINFO, Web of Science, and CINAHL databases (from inception to May 2016). We included randomized co...

    journal_title:Psychiatry research

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.psychres.2017.03.023

    authors: Pu J,Zhou X,Liu L,Zhang Y,Yang L,Yuan S,Zhang H,Han Y,Zou D,Xie P

    更新日期:2017-07-01 00:00:00

  • Behavioral abnormalities in progressive supranuclear palsy.

    abstract::Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder in which, classically, patients present with postural instability and falls, parkinsonism, and slowing of vertical saccades. PSP patients typically have deficits in cognitive functioning, difficulties with most daily activities, and present with...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2013.08.045

    authors: Gerstenecker A,Duff K,Mast B,Litvan I,ENGENE-PSP Study Group.

    更新日期:2013-12-30 00:00:00

  • Pattern-reversed visual evoked potentials in subtypes of major depression.

    abstract::There are no articles in the international psychiatric literature reporting subclinical visual system disorders in depressed patients, although a disturbance of circadian rhythms is one of the prominent theories of the etiopathogenesis of depression. Fifty patients aged 21-60 years suffering from major depression acco...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(03)00097-0

    authors: Fotiou F,Fountoulakis KN,Iacovides A,Kaprinis G

    更新日期:2003-06-15 00:00:00

  • Adherence to physical activity recommendations and physical and mental health risk in people with severe mental illness in Uganda.

    abstract::This study investigated cardio-metabolic risk factors among patients with severe mental illness who do or do not meet the recommendations of 150min per week of physical activity. A secondary aim was to assess whether those that do meet the recommendations report lower levels of mental health symptoms. 107 (60♀) Uganda...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.11.067

    authors: Vancampfort D,Probst M,Basangwa D,De Hert M,Myin-Germeys I,van Winkel R,Ward PB,Rosenbaum S,Mugisha J

    更新日期:2018-02-01 00:00:00

  • The SIENA/FSL whole brain atrophy algorithm is no more reproducible at 3T than 1.5 T for Alzheimer's disease.

    abstract::The back-to-back (BTB) acquisition of MP-RAGE MRI scans of the Alzheimer׳s Disease Neuroimaging Initiative (ADNI1) provides an excellent data set with which to check the reproducibility of brain atrophy measures. As part of ADNI1, 131 subjects received BTB MP-RAGEs at multiple time points and two field strengths of 3T...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2014.07.002

    authors: Cover KS,van Schijndel RA,Popescu V,van Dijk BW,Redolfi A,Knol DL,Frisoni GB,Barkhof F,Vrenken H,neuGRID.,Alzheimer׳s Disease Neuroimaging Initiative.

    更新日期:2014-10-30 00:00:00

  • Does specialization of treatment influence mortality in eating disorders?--A comparison of two retrospective cohorts.

    abstract::Eating disorders (EDs) are psychiatric disorders associated with high morbidity and mortality. It is well established that patients with anorexia nervosa (AN) have an increased risk of premature death, whereas mortality data are lacking for the other EDs. This study aimed to establish mortality rates in a sample of ED...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.08.032

    authors: Winkler LA,Bilenberg N,Hørder K,Støving RK

    更新日期:2015-12-15 00:00:00

  • Neuropsychological frontal impairments and negative symptoms in schizophrenia.

    abstract::Negative symptoms have been associated with frontal lobe dysfunction in schizophrenia. However, neuropsychological studies that evaluated the correlation between performance in tests sensitive to the dorsolateral prefrontal cortex (DLPFC) and negative symptoms have shown inconsistent results. Growing evidence has appe...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2006.03.002

    authors: Martino DJ,Bucay D,Butman JT,Allegri RF

    更新日期:2007-08-30 00:00:00

  • Dissociation, memory commission errors, and heightened autonomic reactivity.

    abstract::If dissociative symptoms are manifestations of a psychological defense mechanism, one would expect people who have such symptoms to react with lower levels of physiological arousal and with memory omissions to emotionally provocative material. The current study tested this assumption in a sample of undergraduates. Six...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2006.04.016

    authors: Giesbrecht T,Geraerts E,Merckelbach H

    更新日期:2007-04-15 00:00:00

  • Cognitive insight and objective quality of life in people with schizophrenia and auditory hallucinations.

    abstract::Poor cognitive insight in schizophrenia has been linked to delusions, hallucinations, and negative symptoms as well as to depressive/anxiety symptoms. Its impact on quality of life has been less studied, especially in schizophrenia subjects with ongoing auditory hallucinations. The Beck Cognitive Insight Scale (BCIS) ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.09.032

    authors: Rathee R,Luhrmann TM,Bhatia T,Deshpande SN

    更新日期:2018-01-01 00:00:00

  • Aggregated COVID-19 suicide incidences in India: Fear of COVID-19 infection is the prominent causative factor.

    abstract::Many Indian COVID-19 suicide cases are turning the press-media attention and flooding in the social media platforms although, no particular studies assessed the COVID-19 suicide causative factors to a large extent. Therefore, the present study presents 69 COVID-19 suicide cases (aged 19 to 65 years; 63 cases were male...

    journal_title:Psychiatry research

    pub_type: 信件

    doi:10.1016/j.psychres.2020.113145

    authors: Dsouza DD,Quadros S,Hyderabadwala ZJ,Mamun MA

    更新日期:2020-08-01 00:00:00

  • Sleep and treatment response in depression: new findings using power spectral analysis.

    abstract::This study examined quantitative measures of sleep electroencephalogram (EEG) and phasic rapid eye movements (REM) as correlates of remission and recovery in depressed patients. To address correlates of remission, pre-treatment EEG sleep studies were examined in 130 women outpatients with major depressive disorder tre...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0165-1781(01)00270-0

    authors: Buysse DJ,Hall M,Begley A,Cherry CR,Houck PR,Land S,Ombao H,Kupfer DJ,Frank E

    更新日期:2001-08-05 00:00:00

  • Aggression as an independent entity even in psychosis - The role of cortisol.

    abstract::Aggression is a common entity in psychiatric disorders, particularly psychotic disorders. Glucocorticoid hypofunction has been linked to abnormal forms of aggressive behavior in various studies in a 'possibly causal' role. We hypothesise that aggression, even among those having psychosis is associated with glucocortic...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.11.002

    authors: Das S,Sengupta S,Pathak K,Sah D,Mehta S,Avinash PR,Baruah A,Deuri SK,Sarmah A,Gogoi V,Kalita KN,Hazarika J

    更新日期:2018-01-01 00:00:00

  • Assessing the opinions of relatives on the causes and social consequences of different mental disorders: are instruments cross-culturally valid?

    abstract::Obtaining valid information about the opinions of relatives on the causes and social consequences of mental disorders should be an important component in specifically tailoring therapeutic interventions for relatives according to their needs. The available range of instruments is small, however, the most prominent bei...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2007.01.007

    authors: Kallert TW,Nitsche I

    更新日期:2008-04-15 00:00:00

  • Do previous experience and geographic proximity matter? Possible predictors for diagnosing Adjustment disorder vs. PTSD.

    abstract::The minority of people who have experienced a traumatic event and were diagnosed as either suffering from PTSD or from Adjustment disorder, may suggest that victims of a traumatic event vary in risk factors for the disorders. The current research aimed at examining the association between reports of Adjustment disorde...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.08.085

    authors: Mahat-Shamir M,Ring L,Hamama-Raz Y,Ben-Ezra M,Pitcho-Prelorentzos S,David UY,Zaken A,Lavenda O

    更新日期:2017-12-01 00:00:00

  • Neuropsychological deficit in schizophrenic subtypes: paranoid, nonparanoid, and schizoaffective subgroups.

    abstract::Schizophrenic patients were carefully diagnosed and screened for a history of neurological disorders. Diagnosis and subtyping was based on DSM-III-R criteria, using the Structured Clinical Interview for DSM-III-R, which was administered by trained interviewers and confirmed by a research psychiatrist. The schizophreni...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(90)90104-d

    authors: Bornstein RA,Nasrallah HA,Olson SC,Coffman JA,Torello M,Schwarzkopf SB

    更新日期:1990-01-01 00:00:00

  • Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.

    abstract::Mild traumatic brain injury (mTBI) is a common occurrence, and may impact distal outcomes in a subgroup of individuals. Improved characterization of health outcomes and identification of factors associated with poor outcomes is needed to better understand the impact of mTBI, particularly in those with co-occurring pos...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.12.021

    authors: Bomyea J,Flashman LA,Zafonte R,Andaluz N,Coimbra R,George MS,Grant GA,Marx CE,McAllister TW,Shutter L,Lang AJ,Stein MB

    更新日期:2019-02-01 00:00:00

  • Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: A study combining mismatch negativity and proton magnetic resonance spectroscopy.

    abstract::Disturbances in the hippocampal glutamate (Glu)/N-methyl-d-aspartate (NMDA) system have been implicated in the pathophysiology of bipolar disorder (BD). Here we aim to provide a targeted integration of two measures of glutamatergic functioning in BD; the association between mismatch negativity (MMN) and in vivo hippoc...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2015.05.002

    authors: Chitty KM,Lagopoulos J,Hickie IB,Hermens DF

    更新日期:2015-08-30 00:00:00

  • Validity and reliability of a scale to assess fatigue.

    abstract::A visual analogue scale to evaluate fatigue severity (VAS-F) was developed and tested in a sample of 75 healthy individuals and a sample of 57 patients undergoing medical evaluation for sleep disorders. The scale consists of 18 items related to fatigue and energy, has simple instructions, and is completed with minimal...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(91)90027-m

    authors: Lee KA,Hicks G,Nino-Murcia G

    更新日期:1991-03-01 00:00:00