Abstract：
:Mild traumatic brain injury (mTBI) is a common occurrence, and may impact distal outcomes in a subgroup of individuals. Improved characterization of health outcomes and identification of factors associated with poor outcomes is needed to better understand the impact of mTBI, particularly in those with co-occurring posttraumatic stress disorder (PTSD). Participants in a data repository of the Injury and Traumatic Stress (INTRuST) Clinical Consortium (n = 625) completed functional disability [FD] and health-related quality of life [HRQOL] questionnaires, and a subset completed a neuropsychological assessment. FD and HRQOL were compared among participants with probable mTBI (mTBI), probable mTBI with PTSD (mTBI/PTSD), and health comparison participants (HC). Associations between symptoms, neuropsychological performance, and health outcomes were examined in those with probable mTBI with and without PTSD (n = 316). Individuals in the mTBI/PTSD group endorsed poorer health outcomes than those in the mTBI group, who endorsed poorer outcomes than those in the HC group. Individuals in either mTBI group performed worse than those in the HC on verbal learning and memory and psychomotor speed. Health outcomes were correlated with mental health and postconcussive symptoms, as well as neuropsychological variables. mTBI may adversely impact self-reported health, with the greatest effect observed in individuals with co-occurring mTBI/PTSD.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Bomyea J,Flashman LA,Zafonte R,Andaluz N,Coimbra R,George MS,Grant GA,Marx CE,McAllister TW,Shutter L,Lang AJ,Stein MBdoi
10.1016/j.psychres.2018.12.021subject
Has Abstractpub_date
2019-02-01 00:00:00pages
531-539eissn
0165-1781issn
1872-7123pii
S0165-1781(17)31659-1journal_volume
272pub_type
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