Abstract：
:There is increasing evidence to suggest both a symptomatic overlap and a clinically significant degree of co-occurrence between Autism Spectrum Disorders (ASD) and psychotic disorders such as schizophrenia but the nature of such relationships remain unclear. We reviewed the literature reporting prevalence rates of Autistic-like Traits (ALTs) and ASD in populations with a diagnosis of schizophrenia or other psychotic disorder. A search of three large databases was conducted and from this seven studies met the criteria for inclusion. The point prevalence rates for ALTs ranged from 9.6% to 61%, whilst the prevalence rates for diagnosed ASD ranged from <1% to 52% across outpatient and inpatient populations. This suggests that prevalence rates of ALTs and ASD in psychosis populations are much higher than in the general population. This has important implications regarding future research, and clinical implications in terms of ensuring that patients receive the most appropriate diagnosis and treatment.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Kincaid DL,Doris M,Shannon C,Mulholland Cdoi
10.1016/j.psychres.2017.01.017subject
Has Abstractpub_date
2017-04-01 00:00:00pages
99-105eissn
0165-1781issn
1872-7123pii
S0165-1781(16)31418-4journal_volume
250pub_type
杂志文章,评审abstract：:A meta-analysis study reported serum brain-derived neurotrophic factor (BDNF) levels as a potential biomarker for schizophrenia. However, at the time, commercially available human ELISA kits were unable to distinguish between pro-BDNF (precursor BDNF) and mature BDNF, because of limited antibody specificity. Here, we ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.12.009
更新日期：2014-02-28 00:00:00
abstract：:Studies which showed anticipation in families with schizophrenia suggested that a trinucleotide repeat expansion mechanism may be involved in the pathogenesis of familial schizophrenia. Furthermore, some studies involving the repeat expansion detection (RED) method showed the median length of CAG repeats to be longer ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(00)00156-6
更新日期：2000-07-17 00:00:00
abstract：:Jumping to conclusions (JTC) is defined as a tendency to make decisions based on insufficient information. JTC has been reported in patients with psychosis, but the mechanisms of this cognitive bias remain unknown. The main aim of our study was to investigate the relationship between JTC and neuropsychological functio...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.01.035
更新日期：2019-03-01 00:00:00
abstract：:There is evidence from research based on self-report personality measures that schizophrenia patients tend to be lower in extraversion and higher in neuroticism than healthy individuals. Self-report personality measures assess aspects of the explicit self-concept. The Implicit Association Test (IAT) has been developed...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.04.023
更新日期：2014-08-30 00:00:00
abstract：:Tobacco smoking is highly prevalent in patients with schizophrenia and alcohol dependence. The underlying neurobiology of nicotine addiction is complex. Rewarding effects of nicotine from cigarettes are associated, among others, with mu-opioid receptors encoded by the OPRM1 gene. The aim of the study was to evaluate t...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113278
更新日期：2020-09-01 00:00:00
abstract：:In schizophrenia patients reduced cerebral asymmetry is an important finding and this may reflect a disturbance in cortical development. We investigated planum temporale (PT) volume and asymmetry in 23 first-episode schizophrenia patients compared to healthy controls and found for the first time an in vivo volume asym...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2011.02.008
更新日期：2011-07-30 00:00:00
abstract：:The primary aim of the present study was to assess the possible associations between dopaminergic, serotonergic, and glutamatergic system-related genes and adverse events after antipsychotic treatment in paranoid schizophrenia patients. The second aim of the study was to compare the intensity of these symptoms between...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2014.05.039
更新日期：2014-10-30 00:00:00
abstract：:Research on neurobiological impairments in clinical and genetic high risk for developing psychosis individuals (CHR) has identified several brain abnormalities that impact both brain structure and function. The current review will discuss research examining brain abnormalities in clinical and genetic high risk for psy...
journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2019.02.009
更新日期：2019-07-01 00:00:00
abstract：:Patients with bipolar mania often require re-hospitalization, which can be a social-economic burden. This study aimed to investigate the factors affecting time to re-hospitalization for inpatients with acute bipolar mania. In this 6-year naturalistic study we reviewed the charts of inpatients with acute bipolar mania....
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.10.073
更新日期：2018-12-01 00:00:00
abstract：:To determine the relationship between Tridimensional Personality Questionnaire (TPQ) scales and bulimia nervosa, TPQ scores of 27 bulimic women, age range 21-59, were compared with values for an age-matched sample of 128 normal control women drawn from the national norming sample by Przybeck. Scores for Novelty Seekin...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0165-1781(93)90108-s
更新日期：1993-07-01 00:00:00
abstract：:Anhedonia has traditionally been considered a characteristic feature of schizophrenia, but the true nature of this deficit remains elusive. This study sought to investigate consummatory and anticipatory pleasure as it relates to motivation deficits. Eighty-four outpatients with schizophrenia and 81 healthy controls we...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.04.040
更新日期：2017-08-01 00:00:00
abstract：:Despite the widespread abuse of marijuana, knowledge about its effects in the human brain is limited. Brain glucose metabolism with and without delta 9 tetrahydrocannabinol (THC) (main psychoactive component of marijuana) was evaluated in eight normal subjects and eight chronic marijuana abusers with positron emission...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(96)02817-x
更新日期：1996-05-31 00:00:00
abstract：:Childhood physical abuse (CPA) has numerous short and long-term negative effects. One of the most serious consequences of CPA is an increased risk for suicide attempts. Clarifying the mechanisms by which CPA increases risk for suicidal behavior may enhance preventive interventions. One potential mechanism is a tendenc...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.07.036
更新日期：2011-02-28 00:00:00
abstract：:The jumping to conclusions bias (JTC), in which some people gather less information than others before making a decision, has been linked to delusions in psychosis. JTC is usually identified via the beads task, in which a sequence of beads (the "target" sequence) is used to measure the amount of evidence participants ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.043
更新日期：2018-07-01 00:00:00
abstract：:Ninety-five patients hospitalized for acute psychosis were reviewed with respect to hallucinogen use and family history of mental illness. Sixty-three percent of admissions had used hallucinogens to some degree within 3 years of the index admission. Drug users were predominantly male, although no age or diagnostic dif...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(83)90030-6
更新日期：1983-06-01 00:00:00
abstract：:There is a growing recognition of the importance of encouraging patients with mental health problems to become more active as an efficacious strategy to reduce the disability-associated burden. The aim of the current study was to investigate if there are differences in quality of life (QoL) outcomes between people wit...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.08.041
更新日期：2017-12-01 00:00:00
abstract：:Borderline personality disorder (BPD) is a severe clinical condition characterised by different maladaptive traits such as impulsivity and affective lability. Mood and emotion dysregulation are core features of affective disorders. Indeed patients affected by mood disorder (MD) have a significantly higher prevalence o...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2011.09.010
更新日期：2012-07-30 00:00:00
abstract：:Suicide is one of the most common causes of death in adolescents. This study identified trends in the prevalence of and factors influencing suicidal ideation and attempts among Korean adolescents. Data were drawn from the third through the thirteenth (2007-2017) annual Korean Youth Risk Behavior Web-based Surveys. Par...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113228
更新日期：2020-09-01 00:00:00
abstract：:In anorexia nervosa (AN), body distortions have been associated with parietal cortex (PC) dysfunction. The PC is also the anatomical substrate of a supramodal reference framework involved in spatial orientation constancy. Given the impaired spatial orientation constancy found in hemineglect, we sought to determine whe...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.08.003
更新日期：2012-01-30 00:00:00
abstract：:Individuals with a more deprived socioeconomic status (SES) are more likely to have higher rates of psychiatric morbidity and use of psychiatric services. Such service use is also influenced by socioeconomic factors at the ecological level. The aim of this article is to investigate the influence of these variables on ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.02.031
更新日期：2013-10-30 00:00:00
abstract：:The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to e...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.07.079
更新日期：2014-12-15 00:00:00
abstract：:This study compared basal concentrations of plasma beta-endorphin/beta-lipotropin-like immunoreactivity and dexamethasone suppression of cortisol in seven chronic pain patients, seven psychiatric disorder patients, and seven normal volunteers. Pain patients and psychiatric patients showed significantly higher basal co...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(83)90005-7
更新日期：1983-08-01 00:00:00
abstract：:Compared rehospitalization rates in patients with schizophrenia or bipolar I disorder to patients with major depressive disorder remains unclear. This study aimed to compare the time to rehospitalization of the three groups. Other clinical variables were also examined. Rehospitalization status was monitored for all ad...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.12.003
更新日期：2010-12-30 00:00:00
abstract：:Evaluation of the outcomes of our decisions may instigate comparisons of our actual outcome with those of others (social comparisons) or comparisons with alternative outcomes of choices not made (private comparisons). Previous research has suggested a deficit in attention to social information among individuals with a...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.01.036
更新日期：2014-05-30 00:00:00
abstract：:Few investigations have assessed the neuropsychological effects of psychotropic medications on schizophrenic patients. In this study, 44 clinically stable schizophrenic inpatients were administered a battery of neuropsychological tests, and their performance was correlated with dosage of neuroleptic medication and ben...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(91)90065-w
更新日期：1991-06-01 00:00:00
abstract：:Limited research has examined differences in well-established suicide correlates between individuals with various histories of suicidality within the ideation to action framework. We hypothesized that individuals without a history of elevated suicidality would exhibit lowest levels of suicide correlates (perceived bur...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.08.038
更新日期：2016-11-30 00:00:00
abstract：:Maternal depression has been intensively explored; however, less attention has been paid to maternal suicide. No studies to date have observed maternal depression and suicide at immediate prenatal and early postpartum stages. In total, 213 Chinese women were recruited in hospitals after they were admitted for childbir...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.12.085
更新日期：2018-03-01 00:00:00
abstract：:One of the recurrent outcomes after a stressor event as a disaster is post-traumatic stress disorder (PTSD), which appears to be mediated, in part, by emotional, behavioral, and psychological responses, arising from the belief system associated with the traumatic experience. Studies suggest that personality traits are...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.04.099
更新日期：2016-07-30 00:00:00
abstract：:In an attempt to clarify the possible role of a serotonergic and dopaminergic dysfunction in obsessive-compulsive disorder (OCD), we measured platelet 3H-imipramine (3H-IMI) binding, serotonin uptake, and platelet sulfotransferase activity in 17 drug-free OCD patients and an equal number of healthy controls. Serotonin...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(92)90037-4
更新日期：1992-04-01 00:00:00
abstract：:The subgenual prefrontal cortex (SGPFC) plays an important role in emotional processing. We carried out a magnetic resonance imaging (MRI) study comparing the volume of the SGPFC in child and adolescent bipolar patients and healthy controls. The sample consisted of 15 children and adolescents who met DSM-IV criteria f...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2004.11.004
更新日期：2005-01-30 00:00:00
