Abstract:
:The neurotrophin, brain-derived neurotrophic factor (BDNF), characterises a probable neurobiochemical explanation of maldevelopments in schizophrenia and is a candidate biomarker of the illness. A paucity of studies examining neurobiochemical predictors of remission in schizophrenia exists. In this study, we seek to examine if serum BDNF level is associated with remission status in a sample of Chinese patients with schizophrenia. This study did not find a significant relationship between serum BDNF and remission in patients with schizophrenia. Identification of a suitable biomarker for diagnosis, management, and prognostic outcome is crucial and warrants further study.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Renjan V,Nurjono M,Lee Jdoi
10.1016/j.psychres.2014.07.079subject
Has Abstractpub_date
2014-12-15 00:00:00pages
193-6issue
1-2eissn
0165-1781issn
1872-7123pii
S0165-1781(14)00658-1journal_volume
220pub_type
杂志文章abstract::Two different initial dosing regimens with clomipramine (CMI) were used to compare early response indicators and dose strategies. Thirty-two inpatients with major depressive disorder were randomized in a double-blind protocol. The pulse-loading group received 150 and 200 mg of CMI on 2 consecutive evenings and then re...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-1781(94)90004-3
更新日期:1994-11-01 00:00:00
abstract::The construction and initial psychometric evaluation of an interview assessment of clinically significant impulsivity (Lifetime History of Impulsive Behaviors; LHIB) is presented. Personality-disordered and control subjects participated by completing self-report measures of depression, anxiety and social desirability,...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2003.12.021
更新日期:2004-04-30 00:00:00
abstract::Haloperidol and reduced haloperidol plasma concentrations were measured in age-matched Chinese and non-Chinese patients (n = 32). Steady-state plasma concentrations were obtained 10-12 hours after the bedtime dose. Haloperidol and reduced haloperidol concentrations were measured by liquid chromatography and radioimmun...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(89)90170-4
更新日期:1989-10-01 00:00:00
abstract::Elevated negative affect is an established link between minor stressors and psychotic symptoms. Less clear is why people with psychosis fail to regulate distressing emotions effectively. This study tests whether subjective, psychophysiological and symptomatic responses to stress can be predicted by specific emotion re...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.04.003
更新日期:2015-08-15 00:00:00
abstract::The cavum septum pellucidum (CSP) is a fluid-filled cavity in the thin midline structure of the septum pellucidum. The CSP has been linked to several neurodevelopmental disorders, but it also occurs as a result of head injury. The aims were to assess the presence and characterization of the CSP in youth with traumatic...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2013.03.001
更新日期:2013-09-30 00:00:00
abstract::The aim was to study the distribution of psychoeducation for anxiety disorders using a two-part survey addressing all psychiatric institutions in Germany, Austria and Switzerland. We found that 77% of the patients with anxiety disorders participated in psychoeducation when it was offered. However, only 8% of the insti...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2008.10.016
更新日期:2009-09-30 00:00:00
abstract::The aim of this study was to develop self-report and clinician-rated versions of an insight scale that would be easy to administer, sensitive to small changes, and inclusive of the core dimensions of clinical insight into psychosis. Ten-item self-report (VAGUS-SR) and five-item clinician-rated (VAGUS-CR) scales were d...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.08.005
更新日期:2014-12-30 00:00:00
abstract::Six patients with bipolar II seasonal affective disorder (SAD) and seven normal control subjects rated their moods in winter at six fixed times each week-day during 1 week of dim and 2 weeks of bright light. The scales rated represent the mood dimension specifically associated with depression, a dimension here called ...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(92)90129-q
更新日期:1992-08-01 00:00:00
abstract::This study reports on the naturalistic pharmacotherapy of 266 youths with bipolar disorder (BP), manic or hypomanic episode (158 males and 108 females, 13.8+/-2.8 years), first treated with monotherapy on valproic acid (VPA) (n=158, 59.4%), lithium (n=90, 33.8%) or atypical antipsychotics (n=18, 6.8%). Among the patie...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.01.022
更新日期:2010-05-15 00:00:00
abstract::This article illustrates how Exploratory Data Analysis (EDA) can complement conventional statistical methods in evaluating psychiatric tests. Using one recent EDA computer program, we evaluated the ability of repeated psychiatric screening tests (the General Health Questionnaire [GHQ]) to predict medical and psychiatr...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(91)90009-e
更新日期:1991-10-01 00:00:00
abstract::Low body mass index (BMI<18/18.5) is utilized as a mandated cutoff for professional fashion model employment, based on assumptions that low BMI indicates eating disorder pathology. No previous studies have examined the association between experimenter-measured BMI and eating disorder symptomatology in professional fas...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113358
更新日期:2020-11-01 00:00:00
abstract::In this study, we aimed to investigate total antioxidative status (TAS) and total oxidative status (TOS) of plasma and antioxidant enzymes such as paraoxonase (PON), stimulated paraoxonase (SPON), arylesterase (ARES) and thiols in plasma of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD)....
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.07.003
更新日期:2015-09-30 00:00:00
abstract::At the beginning of the 2020 New year, novel coronavirus infection continues to affect our lives. The anxiety and stress caused by rising epidemic data, the helplessness and fear caused by city closure and isolation, and the boredom and irritability caused by extended holiday grounding all have a great impact on the p...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2020.113043
更新日期:2020-04-29 00:00:00
abstract::Sensitivity to blood, injury, and mutilation (SBIM) may increase risk for posttraumatic stress disorder (PTSD), given that traumatic events often involve actual or perceived threat of bodily harm to oneself and/or others, including exposure to blood and other mutilation-related stimuli. A self-report questionnaire was...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.058
更新日期:2017-04-01 00:00:00
abstract::The aim of this study was to assess the association between anhedonia and metabolic syndrome (MetS) in a well-characterized community sample of individuals with a current depressive episode. This is a cross-sectional study with young adults aged 24-30 years old. Depressive episode and the presence of anhedonia was ass...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.009
更新日期:2019-01-01 00:00:00
abstract::Despite mounting evidence for the distinctiveness of symptom dimensions in obsessive-compulsive disorder, neuropsychological studies have been few, focused on small samples, and relying on classification of participants based on mutually exclusive symptom categories, resulting in lack of concordance across neuropsycho...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.12.044
更新日期:2017-03-01 00:00:00
abstract::Little is known regarding between-subject variability in the subjective effects of first cocaine use. This study retrospectively assesses the subjective effects of first cocaine use in 160 current treatment-seeking cocaine use disorder patients. Subjective effects of first cocaine use were evaluated with an ad-hoc que...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.03.058
更新日期:2018-06-01 00:00:00
abstract::The processing of social stimuli generated by one's own voluntary behavior is an element of social adaptation. It is known that self-generated stimuli induce attenuated sensory experiences compared with externally generated stimuli. The present study aimed to examine this self-specific attenuation effect on early stim...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.12.037
更新日期:2019-01-01 00:00:00
abstract::The current study aimed to prove the antidepressant-like effects and the probable mechanisms of Schisandrin on depression, which induced by chronic unpredictable mild stress (CUMS) in mice. Four weeks of CUMS exposure resulted in depressive-like behavior, as indicated by the significant decrease in sucrose consumption...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.07.081
更新日期:2017-11-01 00:00:00
abstract::Alzheimer's disease (AD) is clinically characterized by cognitive symptoms that, in combination with behavioral disturbances, significantly interfere with activities of daily living. These behavioral disorders contribute to the clinical heterogeneity of the disease and probably express different pathophysiological pro...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(02)00003-3
更新日期:2002-06-15 00:00:00
abstract::The usefulness of motor subtypes of delirium is unclear due to inconsistency in sub-typing methods and a lack of validation with objective measures of activity. The activity of 40 patients was measured with 24 h accelerometry monitoring. Patients with Diagnostic and Statistical Manual of Mental Disorders, fourth editi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.04.010
更新日期:2010-06-30 00:00:00
abstract::This study compared basal concentrations of plasma beta-endorphin/beta-lipotropin-like immunoreactivity and dexamethasone suppression of cortisol in seven chronic pain patients, seven psychiatric disorder patients, and seven normal volunteers. Pain patients and psychiatric patients showed significantly higher basal co...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(83)90005-7
更新日期:1983-08-01 00:00:00
abstract::The current study was designed to explore the specific relationship between neurologic soft signs (NSSs) and characteristics of antisocial personality traits in adolescents, and to investigate particular NSSs linked to certain brain regions in adolescents with antisocial personality traits. The research was conducted ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.04.023
更新日期:2016-09-30 00:00:00
abstract::Hypersomnia is common in psychiatric disorders, yet there are few self-report measures that adequately characterize this sleep disturbance. The objective of this study was to validate the Hypersomnia Severity Index (HSI), a tool designed to measure severity, distress and impairment of hypersomnia in psychiatric popula...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112547
更新日期:2019-11-01 00:00:00
abstract::The diagnosis of patients suffering from both anxiety and depression is complex due to mixed effects of the two disorders. This complexity has hardened the task to find an adapted treatment for these patients. Consequently, several instruments, known as depression anxiety scales, have been developed and are now used i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.02.074
更新日期:2019-04-01 00:00:00
abstract::Several diffusion tensor imaging (DTI) studies have reported disturbed white matter integrity in various brain regions in patients with schizophrenia, whereas only a few studied the effect of antipsychotics on DTI measures. The aim of this study was to investigate the effect of 12 weeks of clozapine treatment on DTI f...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.06.001
更新日期:2014-09-30 00:00:00
abstract::Schizophrenia is a chronic disorder that is usually characterized by relapses alternating with periods of full or partial remission. We examined whether combined therapy with a psychosocial intervention for relapse prevention (PIRP) and risperidone administered by long-acting injection (RLAI) would be more effective i...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/j.psychres.2008.06.043
更新日期:2010-02-28 00:00:00
abstract::Executive functioning is consistently impaired in schizophrenia, and it has been associated with reduced gray matter volume in prefrontal areas. Abnormalities in prefrontal brain regions have also been related to the illness duration. The aim of the study was to investigate the effect of executive functioning decline ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.10.017
更新日期:2015-02-28 00:00:00
abstract::Suicidal behaviours are highly complex, multi-determined phenomena. Despite this, historically research has tended to focus on bivariate associations between atheoretical demographic and/or psychiatric factors and suicidal behaviour. The aim of this study was to empirically test the Integrated Motivational-Volitional ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.03.023
更新日期:2016-05-30 00:00:00
abstract::The use of Internet has grown in the past number of years, including the increased application of various therapy programs for psychiatric patients which can be accessed online. Few studies investigating psychiatric patients' Internet use exist. Therefore, the aim of this study was to examine the number of psychiatric...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.12.037
更新日期:2015-03-30 00:00:00