Abstract:
:A clear measure of eye movement disorder (EMD) that reliably separated schizophrenic individuals from others would both give insight into the brain control of the disorder and provide an aid in diagnosis. In the present study, a detailed analysis was carried out of the interactions between the pursuit and saccadic components of eye movements at different target velocities. The subjects comprised schizophrenic patients, unipolar depressed patients, and normal controls. The speed of the slow pursuit component did not differ among the groups, but schizophrenic subjects made more saccadic movements at low target velocities, though they started further away from the target at high target velocities. On the basis of these differences, a slope was computed of the linear function that related the number of saccadic eye movements to the velocity of a ramp visual target. Slope direction was negative for schizophrenic subjects but positive for unipolar depressive and normal subjects, and the correct classification rate for subjects was 84%.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Mather JA,Neufeld RW,Merskey H,Russell NCdoi
10.1016/0165-1781(92)90145-ssubject
Has Abstractpub_date
1992-07-01 00:00:00pages
93-109issue
1eissn
0165-1781issn
1872-7123pii
0165-1781(92)90145-Sjournal_volume
43pub_type
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