Hemispheric asymmetry of primary auditory cortex and Heschl's gyrus in schizophrenia and nonpsychiatric brains.


:Heschl's gyrus (HG) is reported to have a normal left>right hemispheric volume asymmetry, and reduced asymmetry in schizophrenia. Primary auditory cortex (A1) occupies the caudal-medial surface of HG, but it is unclear if A1 has normal asymmetry, or whether its asymmetry is altered in schizophrenia. To address these issues, we compared bilateral gray matter volumes of HG and A1, and neuron density and number in A1, in autopsy brains from male subjects with or without schizophrenia. Comparison of diagnostic groups did not reveal altered gray matter volumes, neuron density, neuron number or hemispheric asymmetries in schizophrenia. With respect to hemispheric differences, HG displayed a clear left>right asymmetry of gray matter volume. Area A1 occupied nearly half of HG, but had less consistent volume asymmetry, that was clearly present only in a subgroup of archival brains from elderly subjects. Neuron counts, in layers IIIb-c and V-VI, showed that the A1 volume asymmetry reflected differences in neuron number, and was not caused simply by changes in neuron density. Our findings confirm previous reports of striking hemispheric asymmetry of HG, and additionally show evidence that A1 has a corresponding asymmetry, although less consistent than that of HG.


Psychiatry Res


Psychiatry research


Smiley JF,Hackett TA,Preuss TM,Bleiwas C,Figarsky K,Mann JJ,Rosoklija G,Javitt DC,Dwork AJ




Has Abstract


2013-12-30 00:00:00














  • Set-shifting abilities, mood and loss of control over eating in binge eating disorder: An experimental study.

    abstract::Executive functions play an important role in problem-solving and self-control. Set-shifting is an aspect of executive functioning and represents cognitive flexibility. The inability to control eating in Binge Eating Disorder (BED) may imply deficits in set-shifting which could be exacerbated by negative mood and depr...

    journal_title:Psychiatry research

    pub_type: 杂志文章,多中心研究


    authors: Dingemans AE,Visser H,Paul L,van Furth EF

    更新日期:2015-12-15 00:00:00

  • Moral disengagement and callous unemotional traits configurations in adolescents with disruptive behavior disorder: A person-oriented approach.

    abstract::The interplay between Callous Unemotional Traits (CU) and Moral Disengagement (MD) was examined in a sample of 90 adolescents with Disruptive Behavior Disorders. Using a person-centered approach, three CU and MD configurations were identified, attesting the strong relationship between these two moral dimensions. Howev...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Paciello M,Masi G,Clemente MG,Milone A,Muratori P

    更新日期:2017-12-01 00:00:00

  • An exploratory study of evoked facial affect in adolescent females with anorexia nervosa.

    abstract::The aim of this exploratory study was to investigate facial affect in adolescent females with anorexia nervosa (AN). Evoked facial affect was recorded whilst AN and control participants (n=34) viewed emotional films. Significantly less facial affect was found in AN adolescents, despite reporting no differences in subj...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Rhind C,Mandy W,Treasure J,Tchanturia K

    更新日期:2014-12-15 00:00:00

  • Sex differences in hedonic judgement of odors in schizophrenia cases and healthy controls.

    abstract::The neurocircuitries subserving affective and olfactory processes overlap, are sexually dimorphic, and show disruptions in schizophrenia, suggesting their intersection may be a window on the core process producing psychosis. This study investigated diagnostic and sex differences in hedonic judgments of odors and smell...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Walsh-Messinger J,Wong PS,Antonius D,McMahon K,Opler LA,Ramirez PM,Malaspina D

    更新日期:2018-11-01 00:00:00

  • FDG-PET and CSF phospho-tau for prediction of cognitive decline in mild cognitive impairment.

    abstract::Specific patterns of cortical glucose metabolism disturbances and increased CSF phospho-tau (p-tau(181)) concentrations could be demonstrated to predict cognitive decline and shift to dementia in amnestic mild cognitive impairment (MCI). But comparisons of both diagnostic tools have not been undertaken so far. The aim...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Fellgiebel A,Scheurich A,Bartenstein P,Müller MJ

    更新日期:2007-07-15 00:00:00

  • A computer program for assessing interexaminer agreement when multiple ratings are made on a single subject.

    abstract::This report describes a computer program for applying a new statistical method for determining levels of agreement, or reliability, when multiple examiners evaluate a single subject. The statistics that are performed include the following: an overall level of agreement, expressed as a percentage, that takes into accou...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Cicchetti DV,Showalter D

    更新日期:1997-08-29 00:00:00

  • Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.

    abstract::Mild traumatic brain injury (mTBI) is a common occurrence, and may impact distal outcomes in a subgroup of individuals. Improved characterization of health outcomes and identification of factors associated with poor outcomes is needed to better understand the impact of mTBI, particularly in those with co-occurring pos...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Bomyea J,Flashman LA,Zafonte R,Andaluz N,Coimbra R,George MS,Grant GA,Marx CE,McAllister TW,Shutter L,Lang AJ,Stein MB

    更新日期:2019-02-01 00:00:00

  • Early signs of worry: psychosis risk symptom visual distortions are independently associated with suicidal ideation.

    abstract::Previous studies have shown an association between suicidal behavior and schizophrenia. However, little is known about this association in those with psychotic experiences and symptoms that do not meet the criteria for full psychosis. The aim of the study was to investigate how psychosis risk symptoms are associated w...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Granö N,Salmijärvi L,Karjalainen M,Kallionpää S,Roine M,Taylor P

    更新日期:2015-02-28 00:00:00

  • Cortical thickness differences in the prefrontal cortex in children and adolescents with ADHD in relation to dopamine transporter (DAT1) genotype.

    abstract::Several lines of evidence suggest that the dopamine transporter gene (DAT1) plays a crucial role in attention deficit hyperactivity disorder (ADHD). Concretely, recent data indicate that the 10-repeat (10R) DAT1 allele may mediate neuropsychological functioning, response to methylphenidate, and even brain function and...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Fernández-Jaén A,López-Martín S,Albert J,Fernández-Mayoralas DM,Fernández-Perrone AL,de La Peña MJ,Calleja-Pérez B,Rodríguez MR,López-Arribas S,Muñoz-Jareño N

    更新日期:2015-09-30 00:00:00

  • Emotional sensitivity in youth with borderline personality pathology.

    abstract::If Borderline Personality Disorder (BPD) is characterized by an underlying emotional sensitivity, individuals with this disorder would be expected to demonstrate accurate identification of emotional expressions at earlier stages of expression (i.e., lower thresholds of facial expressivity across all emotional valences...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Jovev M,Chanen A,Green M,Cotton S,Proffitt T,Coltheart M,Jackson H

    更新日期:2011-05-15 00:00:00

  • Profiles of the antipanic compounds, triazolobenzodiazepines and phenelzine, in two animal tests of anxiety.

    abstract::Two animal tests of anxiety (the elevated plus-maze and the social interaction test) were used to investigate the effects of several antipanic agents. In the elevated plus-maze, the triazolobenzodiazepines adinazolam (2 and 5 mg/kg) and alprazolam (1 mg/kg), tested after 5 days of pretreatment, demonstrated significan...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Johnston AL,File SE

    更新日期:1988-07-01 00:00:00

  • Analysis of catechol-O-methyltransferase and 5-hydroxytryptamine transporter polymorphisms in patients at risk for suicide.

    abstract::Genotype frequencies of functional polymorphisms in the genes encoding the serotonin transporter (5-HTT) and the enzyme catechol-O-methyltransferase (COMT) were not different in 51 suicidal inpatients compared to 51 control subjects. Within the patient group, increased hopelessness and suicide ideation were associated...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Russ MJ,Lachman HM,Kashdan T,Saito T,Bajmakovic-Kacila S

    更新日期:2000-02-14 00:00:00

  • Caffeine taste test for panic disorder: adenosine receptor supersensitivity.

    abstract::The present study introduces a novel measure of adenosine receptor sensitivity that is based on the action of specific receptor blockers (e.g., caffeine) to potentiate the ability to detect threshold quinine concentrations. The test is used to compare gustatory adenosinergic responses to caffeine challenges in normal ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: DeMet E,Stein MK,Tran C,Chicz-DeMet A,Sangdahl C,Nelson J

    更新日期:1989-12-01 00:00:00

  • Progressive membrane phospholipid changes in first episode schizophrenia with high field magnetic resonance spectroscopy.

    abstract::Patients with a first episode of schizophrenia generally have increased phospholipid membrane breakdown products within the brain, while findings in chronic patients have been inconsistent. In this study we examine progressive changes in phosphorus membrane metabolites in the same patient group through the early years...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Miller J,Drost DJ,Jensen E,Manchanda R,Northcott S,Neufeld RW,Menon R,Rajakumar N,Pavlosky W,Densmore M,Schaefer B,Williamson P

    更新日期:2012-01-30 00:00:00

  • The association between satisfaction with husband's participation in housework and suicidal ideation among married working women in Korea.

    abstract::Although married women are increasingly participating in paid labor, housework remains their primary responsibility. This uneven distribution of housework could have a negative impact on their mental health. In this study, we examined the association between satisfaction with husbands' participation in housework and s...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Lee SA,Park EC,Ju YJ,Han KT,Yoon HJ,Kim TH

    更新日期:2018-03-01 00:00:00

  • Altered pineal serotonin binding in some suicides.

    abstract::Serotonergic abnormalities have been regularly reported in the brains of suicide victims. Because of evidence that pineal function is altered in depressed subjects and that serotonin-releasing axons may innervate the pineal, we assayed tritiated serotonin binding in a series of control and suicide pineals. High affini...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Sparks DL,Little KY

    更新日期:1990-04-01 00:00:00

  • Prevalence of binge-eating and bulimia among adolescent women in Japan.

    abstract::This study examined by questionnaire the prevalence of binge-eating and bulimia among 220 women at a school of nursing and 236 women at a junior college, all from 18 to 21 years old, in two different areas of Japan. Binge-eating more than once a week was found in 14 (6.5%) of the nursing school students and 21 (9.1%) ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Kiriike N,Nagata T,Tanaka M,Nishiwaki S,Takeuchi N,Kawakita Y

    更新日期:1988-11-01 00:00:00

  • Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis.

    abstract::Medication non-adherence is one of the major obstacles to recovery in first-episode psychosis (FEP). This study aimed to identify the predictors and rates of medication non-adherence in the first and second year after the start of treatment (baseline) in urban Chinese FEP patients. Relevant information on medication n...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Lai-Ming Hui C,Wing-Yan Poon V,Shuk-Kuen Kwok V,Chang WC,Kit-Wa Chan S,Ho-Ming Lee E,Yu-Hai Chen E

    更新日期:2015-08-30 00:00:00

  • Correlations between executive function, decision-making and impulsivity are disrupted in schizophrenia versus controls.

    abstract::Schizophrenia (n=68) and control (n=62) participants matched on cigarette smoking history were assessed on executive function, decision-making and impulsivity tasks. In controls, executive function and decision-making correlated positively with each other and negatively with impulsivity. There were no inter-task corre...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Wing VC,Rabin RA,Wass CE,George TP

    更新日期:2013-01-30 00:00:00

  • The burden of disability in children and youths associated with impairments of psychological functions.

    abstract::The immense burden of health conditions in children that is associated with mental disorders worldwide is increasingly being recognized. In comparison, the burden of disability associated with children's impairments of psychological functions (IPFs) is not well documented. The goal of this population-based study was t...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Baillargeon RH,Bernier J

    更新日期:2010-05-15 00:00:00

  • Changes in locomotor response to beta-endorphin microinfusion during and after opiate abstinence syndrome--a proposal for a model of the onset of mania.

    abstract::Beta-Endorphin (0.3 or 0.6 nanomoles) was infused into the A10-ventral tegmental area (VTA) of male Wistar rats previously treated for 6 days with either morphine sulfate or lactose via subcutaneously implanted silastic pellets. Beta-Endorphin microinfusions occurred at 24 and 96 hours after pellets were removed. Prof...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Schwartz JM,Ksir C,Koob GF,Bloom FE

    更新日期:1982-10-01 00:00:00

  • The ventricular-brain ratio on computed tomography scans: validity and proper use.

    abstract::The planimetric measurement of the area of the ventricles on a computed tomographic section is a convenient and useful method of assessing ventricular size when more sophisticated techniques are not available. It is commonly reported as a planimetric ventricular-brain ratio or VBR. Ventricular size is related to crani...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Zatz LM,Jernigan TL

    更新日期:1983-03-01 00:00:00

  • Pattern-reversed visual evoked potentials in subtypes of major depression.

    abstract::There are no articles in the international psychiatric literature reporting subclinical visual system disorders in depressed patients, although a disturbance of circadian rhythms is one of the prominent theories of the etiopathogenesis of depression. Fifty patients aged 21-60 years suffering from major depression acco...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Fotiou F,Fountoulakis KN,Iacovides A,Kaprinis G

    更新日期:2003-06-15 00:00:00

  • Preliminary investigation of the impulsive and neuroanatomical characteristics of compulsive sexual behavior.

    abstract::In recent years, there has been increased interest in a clinical syndrome characterized by excessive sexual thoughts, sexual urges, and/or sexual behaviors that has many aspects in common with impulse control disorders. This study provides a preliminary examination of the impulsive aspects of this syndrome, compulsive...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Miner MH,Raymond N,Mueller BA,Lloyd M,Lim KO

    更新日期:2009-11-30 00:00:00

  • Associations between depression subtypes and substance use disorders.

    abstract::Evaluating whether certain subtypes of Major Depressive Disorder (MDD) are more strongly associated with Substance Use Disorders (SUDs) may help clarify reasons for MDD-SUD relations. Therefore, this study compared DSM-IV-defined non-atypical/non-melancholic depression (undifferentiated depression; n=365), atypical de...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Leventhal AM,Francione Witt C,Zimmerman M

    更新日期:2008-10-30 00:00:00

  • No evidence of linkage between the dopamine D2 receptor gene and schizophrenia.

    abstract::The antipsychotic effects of dopamine D2 receptor antagonists (neuroleptics) and the psychotomimetic effects of dopamine agonists suggest that a defect of the D2 receptor gene might be a factor in the etiology of schizophrenia. Fifteen families that contained several members suffering from schizophrenia were tested fo...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Hallmayer J,Maier W,Schwab S,Ertl MA,Minges J,Ackenheil M,Lichtermann D,Wildenauer DB

    更新日期:1994-08-01 00:00:00

  • Tobacco use does not influence the response to non-pharmacologic depression treatment: A secondary analysis of the Regassa randomized controlled trial.

    abstract::Behavioural interventions show promising results among patients with mild- to moderate depression. However, whether tobacco use moderates the effects of these interventions is not known. In the present study, we examined whether patients suffering from mild-to-moderate depression differed in their response to prescrib...

    journal_title:Psychiatry research

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Rahman MS,Forsell Y,Hallgren M,Galanti MR

    更新日期:2018-03-01 00:00:00

  • Differences in the symptom profile of methamphetamine-related psychosis and primary psychotic disorders.

    abstract::We examined the lifetime experience of hallucinations and delusions associated with transient methamphetamine-related psychosis (MAP), persistent MAP and primary psychosis among a cohort of dependent methamphetamine users. Participants were classified as having (a) no current psychotic symptoms, (n=110); (b) psychotic...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: McKetin R,Baker AL,Dawe S,Voce A,Lubman DI

    更新日期:2017-05-01 00:00:00

  • What your eyes tell me: Theory of mind in bipolar disorder.

    abstract::The aim of this study was to assess social- perceptual Theory of Mind in bipolar disorder (BD). 112 euthymic participants with BD I or BD II (65 with BD I and 47 with BD II) were compared to a group of 112 persons with no psychiatric diagnosis and 43 with unipolar depression (UD). They completed the task of the "Readi...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Espinós U,Fernández-Abascal EG,Ovejero M

    更新日期:2018-04-01 00:00:00

  • Blast exposure interacts with genetic variant 5HTTLPR to predict posttraumatic stress symptoms in military explosives personnel.

    abstract::The first of its kind, this study determined whether blast exposure interacts with genetic variant 5HTTLPR to predict posttraumatic stress (PTS) symptoms in 78 military explosives operators. In all models, blast-exposed 5HTTLPR S carriers registered definitively higher PTS symptoms in comparison to non-exposed S carri...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Taylor MK,Hernández LM,Stump J,Tschiffely AE,Goforth CW,Laver DC,Ahlers ST

    更新日期:2019-10-01 00:00:00