Abstract：
:The utility of non-invasive brain stimulation techniques to alleviate resistant delusions in schizophrenia is an under-researched area. In this study, we report the effectiveness of alpha transcranial alternating current stimulation (tACS) targeting the medial prefrontal cortex in ameliorating persistent delusions. Twelve Schizophrenia patients (N=12) with persistent delusions received add-on treatment with a twice-daily 20-minutes session of 10-Hz tACS. Significant reduction in severity of delusion was noted after 5th day (z=2.67, p<0.01, n=12) with further improvement after 10th day (z=2.52, p=0.01, n=9) of stimulation. Add-on treatment with 10-Hz tACS is a potential therapeutic option for treatment-resistant delusions, which requires further systematic research.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Sreeraj VS,Suhas S,Parlikar R,Selvaraj S,Dinakaran D,Shivakumar V,Narayanaswamy JC,Venkatasubramanian Gdoi
10.1016/j.psychres.2020.113106subject
Has Abstractpub_date
2020-08-01 00:00:00pages
113106eissn
0165-1781issn
1872-7123pii
S0165-1781(20)30575-8journal_volume
290pub_type
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