Status of natural infection with Japanese encephalitis virus in Japan: prevalence of antibodies to the nonstructural 1 protein among humans and horses.

abstract：BACKGROUND:BCR/ABL and Wilms' tumor 1 (WT1) are an ideal tumor associated antigens which can be used to develop a potential chronic myeloid leukemia (CML) dentritic cell (DC) vaccine. Here, we constructed a novel polyepitope vaccine which used recombinant lentiviral vector carrying BCR/ABL and WT1 genes, and determined...

journal_title：Vaccine

authors： Dong W,Zhang J,Shao N,Tian T,Li L,Jian J,Zang S,Ma D,Ji C

更新日期：2014-06-12 00:00:00

abstract：:Cell substrate DNA was shown to be an abundant contaminant in the clarified preparations of the Sabin type 1, 2 and 3 poliovaccines produced on a continuous cell line (4647). The size of the DNA, as evaluated for the Sabin type 1 poliovaccine, was highly heterogeneous, ranging from 100 to 20,000 base pairs. In view of...

journal_title：Vaccine

authors： Amosenko FA,Svitkin YV,Popova VD,Terletskaya EN,Timofeev AV,Elbert LB,Lashkevich VA,Drozdov SG

更新日期：1991-03-01 00:00:00

abstract：:In March 2010, Brazil introduced the 10-valent pneumococcal conjugate vaccine (PCV10) in the routine infant immunization program using a 4-dose schedule and catch-up for children <23months. We investigated PCV10 effect on nasopharyngeal carriage with vaccine-type Streptococcus pneumoniae (Spn) and non-typeable Haemoph...

journal_title：Vaccine

authors： Brandileone MC,Zanella RC,Almeida SCG,Brandao AP,Ribeiro AF,Carvalhanas TMP,Sato H,Andrade AL,Verani JR,Pneumococcal Carriage Study Group.

更新日期：2016-11-04 00:00:00

abstract：:Bovine viral diarrhea virus (BVDV) represents a major cattle disease with multiple forms including fetal infections resulting in persistently infected (PI) cattle. The objectives of this study were to investigate the immune response to six vaccines, five modified live viral (MLV) and one killed vaccine containing BVDV...

journal_title：Vaccine

authors： Fulton RW,Cook BJ,Payton ME,Burge LJ,Step DL

更新日期：2020-05-19 00:00:00

abstract：:During the years 2009 and 2010 relevant epidemic waves of foot-and-mouth disease (FMD) serotype O occurred in Ecuador, representing a great drawback for the last stages of the ongoing eradication program in South America. This study describes the molecular and antigenic characterizations of 29 isolates collected from ...

journal_title：Vaccine

authors： Maradei E,Perez Beascoechea C,Malirat V,Salgado G,Seki C,Pedemonte A,Bonastre P,D'Aloia R,La Torre JL,Mattion N,Rodríguez Toledo J,Bergmann IE

更新日期：2011-10-26 00:00:00

abstract：INTRODUCTION:Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988, there has been a tremendous progress in the reduction of cases of poliomyelitis. The world is on the verge of achieving global polio eradication and in May 2013, the 66th World Health Assembly endorsed the Polio Eradication and End...

journal_title：Vaccine

authors： Mwengee W,Okeibunor J,Poy A,Shaba K,Mbulu Kinuani L,Minkoulou E,Yahaya A,Gaturuku P,Landoh DE,Nsubuga P,Salla M,Mihigo R,Mkanda P

更新日期：2016-10-10 00:00:00

abstract：:A gene associated with lipopolysaccharide (LPS) transport was cloned from a local clinical Vibrio cholerae O1 strain of the Ogawa serotype by using the Lactococcus lactis nisin-controlled expression (NICE) system. The V. cholerae wzm gene, which codes for an integral membrane transporter protein, was expressed and tar...

journal_title：Vaccine

authors： Zamri HF,Shamsudin MN,Rahim RA,Neela V

更新日期：2012-05-02 00:00:00

abstract：:In a study to develop novel vaccination strategies against tuberculosis, we encapsulated DNA encoding Ag85B, MPT-64 and MPT-83 antigens mixed with dimethyldioctyldecyl ammonium bromide (DDA) into biodegradable poly(dl-lactide-co-glycolide, PLGA) microspheres. Scanning electron microscopy (SEM) analysis demonstrated a ...

journal_title：Vaccine

authors： Cai H,Hu XD,Yu DH,Li SX,Tian X,Zhu YX

更新日期：2005-07-14 00:00:00

abstract：:Surface proteins from several different life-cycle stages of the malaria parasite Plasmodium falciparum were expressed at high levels in the yeast Saccharomyces cerevisiae. Purified proteins, both individually and in cocktails, were used to immunize mice and goats in conjunction with either Freund's adjuvant or a mura...

journal_title：Vaccine

authors： Bathurst IC,Gibson HL,Kansopon J,Hahm BK,Green KM,Chang SP,Hui GS,Siddiqui WA,Inselburg J,Millet P

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Public health authorities have the resources to conduct efficient immunization reminder interventions to improve vaccine uptake. The objective of this initiative was to design and implement a cost-effective centralized HPV vaccine reminder using New York State Immunization Information System data as one of f...

journal_title：Vaccine

authors： Coley S,Hoefer D,Rausch-Phung E

更新日期：2018-08-06 00:00:00

abstract：:The bacillus Calmette Guérin (BCG) vaccine, the only licensed vaccine against TB, displays partial and variable efficacy, thus making the exploitation of novel vaccination strategies a major priority. Most of the current vaccines in pre-clinical or clinical development are based on the induction of T cells recognizing...

journal_title：Vaccine

authors： Larrouy-Maumus G,Layre E,Clark S,Prandi J,Rayner E,Lepore M,de Libero G,Williams A,Puzo G,Gilleron M

更新日期：2017-03-07 00:00:00

abstract：BACKGROUND:As with many high-income countries, vaccination coverage against human papilloma virus (HPV) infection is not high in New Zealand (NZ) at 47% in school-aged girls for three doses. We estimate the health gains, net-cost and cost-effectiveness of the currently implemented HPV national vaccination programme of ...

journal_title：Vaccine

authors： Blakely T,Kvizhinadze G,Karvonen T,Pearson AL,Smith M,Wilson N

更新日期：2014-05-07 00:00:00

abstract：:We reported previously on the development of a Bacillus anthracis vaccine strain expressing high levels of recombinant protective antigen (rPA) [Cohen et al., Infec Immun 2000;68(8):4549-58]. To further explore the potential of the B. anthracis platform, we generated several attenuated strains expressing lethal toxin ...

journal_title：Vaccine

authors： Mendelson I,Gat O,Aloni-Grinstein R,Altboum Z,Inbar I,Kronman C,Bar-Haim E,Cohen S,Velan B,Shafferman A

更新日期：2005-12-01 00:00:00

abstract：:Vaccination is the best available measure of limiting the impact of the next influenza pandemic. Ideally, a candidate pandemic influenza vaccine should be easy to administer and should elicit strong mucosal and systemic immune responses. Production of influenza subunit antigen in transient plant expression systems is ...

journal_title：Vaccine

authors： Madhun AS,Haaheim LR,Nøstbakken JK,Ebensen T,Chichester J,Yusibov V,Guzman CA,Cox RJ

更新日期：2011-07-12 00:00:00

abstract：INTRODUCTION:It is suspected that Web 2.0 web sites, with a lot of user-generated content, often support viewpoints that link autism to vaccines. METHODS:We assessed the prevalence of the views supporting a link between vaccines and autism online by comparing YouTube, Google and Wikipedia with PubMed. Freedom of speec...

journal_title：Vaccine

authors： Venkatraman A,Garg N,Kumar N

更新日期：2015-03-17 00:00:00

abstract：:A carcinoembryonic antigen (CEA)-based DNA vaccine, adsorbed onto cationic microparticles of poly(DL-lactide-co-glycolide) (PLG) induced tumor-protective immunity against a lethal challenge of MC38-CEA colon carcinoma cells in CEA-transgenic mice that was more potent than that of the corresponding naked DNA vaccine. B...

journal_title：Vaccine

authors： Luo Y,O'Hagan D,Zhou H,Singh M,Ulmer J,Reisfeld RA,James Primus F,Xiang R

更新日期：2003-05-16 00:00:00

abstract：:Induction of broad HIV-1 neutralizing antibodies should be a major goal of an effective HIV-1 vaccine. However, B cells are severely damaged during HIV-1 infection with loss of memory B cells and decline of serological memory. The molecular events leading to B cell damage must be further characterized with the aim of ...

journal_title：Vaccine

authors： Cagigi A,Nilsson A,De Milito A,Chiodi F

更新日期：2008-06-06 00:00:00

abstract：:Bluetongue virus (BTV) antibodies were analysed in 27 Swiss calves born in 2016 at the age of 16-19 days using competitive enzyme-linked-immunosorbent-assay (cELISA) and virus neutralization test (VNT) (animal trial permission number: 75684). Obligatory documentation proved that 15 of 27 dams were BTV-8 vaccinated onc...

journal_title：Vaccine

authors： Ayrle H,Mevissen M,Kaske M,Vögtlin A,Fricker R,Hoffmann B,Büttner M,Marinovic Z,Walkenhorst M

更新日期：2018-09-18 00:00:00

abstract：:The hepatitis E virus (HEV) vaccine, Hecolin(®), was licensed in China for the prevention of HEV infection and HEV-related diseases with demonstrated safety and efficacy [1,2]. The vaccine is composed of a truncated HEV capsid protein, p239, as the sole antigen encoded by open reading frame 2 and produced using Escher...

journal_title：Vaccine

authors： Zhang X,Wei M,Pan H,Lin Z,Wang K,Weng Z,Zhu Y,Xin L,Zhang J,Li S,Xia N,Zhao Q

更新日期：2014-07-07 00:00:00

abstract：:Activation of the innate immune system by different homotopes may direct the subsequent specific immune response, and as a consequence may have significant implications on vaccination. In this study, effects of i.v. administered lipopolysaccharide (LPS), and lipoteichoic acid (LTA), respectively, and s.c. administered...

journal_title：Vaccine

authors： Maldonado LM,Lammers A,Nieuwland MG,De Vries Reilingh G,Parmentier HK

更新日期：2005-04-15 00:00:00

abstract：:Due to ongoing recombination and mutations, HIV permanently escapes from neutralizing antibody (nAb) responses of the host. By the masking of epitopes or shedding of gp120, HIV-1 further impedes an efficient neutralization by Abs. Therefore, nAbs responses of the host are chasing behind a rapidly evolving virus and ma...

journal_title：Vaccine

authors： Stoiber H,Soederholm A,Wilflingseder D,Gusenbauer S,Hildgartner A,Dierich MP

更新日期：2008-12-30 00:00:00

abstract：:Although vaccination has had a dramatic impact on reducing economic losses due to infectious diseases, vaccination technology has not changed dramatically over the last 200 years. However, with the advent of biotechnology and our understanding of virulence factors of infectious agents combined with our knowledge of th...

journal_title：Vaccine

authors： Babiuk LA

更新日期：1999-03-26 00:00:00

abstract：:A WHO workshop organized following the 2009 H1N1 pandemic recommended development of alternative influenza vaccine potency assays as high priority that could expedite the release of vaccine lots in the face of future influenza pandemics. We have developed an antibody independent, simple, high throughput receptor-bindi...

journal_title：Vaccine

authors： Khurana S,King LR,Manischewitz J,Coyle EM,Golding H

更新日期：2014-04-17 00:00:00

abstract：:Wildebeest-associated malignant catarrhal fever (WA-MCF), a fatal disease of cattle caused by alcelaphine herpesvirus 1 (AlHV-1), is one of the most important seasonal diseases of cattle in wildebeest endemic areas, with annual incidence reaching 10%. Here we report efficacy of over 80% for a vaccine based on the atte...

journal_title：Vaccine

authors： Cook E,Russell G,Grant D,Mutisya C,Omoto L,Dobson E,Lankester F,Nene V

更新日期：2019-09-20 00:00:00

abstract：:Currently, infections of hand, foot and mouth disease (HFMD) due to Human Enterovirus 71 (EV71) cannot be prevented or treated, as there are no suitable vaccines or antiviral drugs. This study aimed to identify potential vaccine candidates for EV71 using in silico analysis of its viral capsid proteins. A combined in s...

journal_title：Vaccine

authors： Kirk K,Poh CL,Fecondo J,Pourianfar H,Shaw J,Grollo L

更新日期：2012-11-19 00:00:00

abstract：:Defective interfering (DI) virus RNAs result from major deletions in full-length viral RNAs that occur spontaneously during de novo RNA synthesis. These RNAs are packaged into virions that are by definition non-infectious, and are delivered to cells normally targeted by the virion. DI RNAs can only replicate with the ...

journal_title：Vaccine

authors： Mann A,Marriott AC,Balasingam S,Lambkin R,Oxford JS,Dimmock NJ

更新日期：2006-05-15 00:00:00

abstract：:Comparative analyses of murine dendritic cells (DC) isolated from the skin and from the intestinal mucosa after exposure to cholera toxin and its non-toxic B subunit disclose striking differences regarding the migratory and functional behaviour of these cells. The nature of the epithelial microenvironment, especially ...

journal_title：Vaccine

authors： Anjuère F,Luci C,Hervouet C,Rousseau D,Czerkinsky C

更新日期：2006-04-12 00:00:00

abstract：:Twenty-nine classical swine fever virus (CSFv) strains were grown in the PK15 or SK6 cell lines. Antigenic differentiation studies were performed using monoclonal antibodies (McAbs), produced at Lelystad (CDI-DLO), The Netherlands. The monoclonals which were classified numerically as monoclonals 2-13. Epitope map patt...

journal_title：Vaccine

authors： Mendoza S,Correa-Giron P,Aguilera E,Colmenares G,Torres O,Cruz T,Romero A,Hernandez-Baumgarten E,Ciprián A

更新日期：2007-10-10 00:00:00

abstract：:Gram-negative bacterial outer membrane proteins (Omps) have an important role in pathogenesis and signal reception. We previously reported that Acinetobacter OmpA (AbOmpA) induced maturation of bone marrow-derived dendritic cells (BMDCs) and that AbOmpA-primed DCs produced IL-12 which generated Th1 CD4(+) T-cells. We ...

journal_title：Vaccine

authors： Jang MJ,Kim JE,Chung YH,Lee WB,Shin YK,Lee JS,Kim D,Park YM

更新日期：2011-03-16 00:00:00

abstract：:Japanese encephalitis is a major cause of encephalitis in Asia. Cases occur largely in rural areas of the South and East Asian region resulting in significant morbidity and mortality. Multiple vaccines exist to control Japanese encephalitis, but all suffer from problems. Envelope protein domain III of Japanese encepha...

journal_title：Vaccine

authors： Verma SK,Kumar S,Gupta N,Vedi S,Bhattacharya SM,Lakshmana Rao PV

更新日期：2009-11-16 00:00:00